AutismKB 2.0

Annotation Detail for NGFRAP1


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Basic Information Top
Gene Symbol:NGFRAP1 ( BEX3,Bex,DXS6984E,HGR74,NADE )
Gene Full Name: nerve growth factor receptor (TNFRSF16) associated protein 1
Band: Xq22.2
Quick LinksEntrez ID:27018; OMIM: 300361; Uniprot ID:BEX3_HUMAN; ENSEMBL ID: ENSG00000166681; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus25 / 56401244
neonate1 / 3109732
infant1 / 2362042
juvenile2 / 5555635
adult131 / 193912167
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma1 / 1068839
head and neck tumor12 / 13630288
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal169 / 336030750
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer16 / 102680155
retinoblastoma1 / 4635621
skin tumor6 / 12494948
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain38 / 110098934
cervix0 / 481710 
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye6 / 21105428
heart10 / 89626111
intestine4 / 23447217
kidney7 / 21177733
larynx4 / 24145165
liver16 / 20774377
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas24 / 214812111
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta21 / 28082574
prostate31 / 189345163
salivary gland0 / 201550 
skin12 / 21057456
spleen1 / 5395218
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid12 / 47473252
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217963_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.1
Adipocyte1371.6
AdrenalCortex1569.25
Adrenalgland2527.9
Amygdala7843.3
Appendix720.85
AtrioventricularNode190.55
BDCA4+_DentriticCells74.4
Bonemarrow234
BronchialEpithelialCells1659.75
CD105+_Endothelial419.25
CD14+_Monocytes74.35
CD19+_BCells(neg._sel.)107.3
CD33+_Myeloid54.9
CD34+2133.85
CD4+_Tcells210.55
CD56+_NKCells92.3
CD71+_EarlyErythroid35.7
CD8+_Tcells247.45
CardiacMyocytes866.6
Caudatenucleus4548.2
Cerebellum2352.5
CerebellumPeduncles3442.25
CiliaryGanglion463.4
CingulateCortex4977.65
Colorectaladenocarcinoma1134.4
DorsalRootGanglion580.2
FetalThyroid2835.7
Fetalbrain2674.55
Fetalliver873.85
Fetallung1278.85
GlobusPallidus3805.65
Heart1074.9
Hypothalamus8939.5
Kidney1318.1
Leukemia_chronicMyelogenousK-56261.15
Leukemia_promyelocytic-HL-6032.05
Leukemialymphoblastic(MOLT-4)1361.45
Liver694.1
Lung1808
Lymphnode349.4
Lymphoma_burkitts(Daudi)63.55
Lymphoma_burkitts(Raji)61
MedullaOblongata3701.8
OccipitalLobe5624.5
OlfactoryBulb1327.25
Ovary1253.2
Pancreas285.3
PancreaticIslet990.95
ParietalLobe4596.4
Pituitary5442.55
Placenta1689.6
Pons3093.25
PrefrontalCortex5696.2
Prostate2300
Salivarygland309.95
SkeletalMuscle63.95
Skin142.55
SmoothMuscle2074.7
Spinalcord4563.1
SubthalamicNucleus4287
SuperiorCervicalGanglion350.1
TemporalLobe4312.8
Testis2451.55
TestisGermCell3018.55
TestisIntersitial886.8
TestisLeydigCell1267.9
TestisSeminiferousTubule1280.15
Thalamus5034.3
Thymus892.95
Thyroid5362.05
Tongue213.7
Tonsil100.25
Trachea483.8
TrigeminalGanglion510.3
Uterus1435.35
UterusCorpus564.85
WholeBlood301.8
Wholebrain7934.05
colon846.95
pineal_day5418.04
pineal_night5890.78
retina2714.325
small_intestine714.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P45524
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.47 ± 0.31
Basal Forebrain13.38 ± 0.31
Basal Part of Pons13.64 ± 0.25
Cerebellar Cortex13.38 ± 0.21
Cerebellar Nuclei13.61 ± 0.23
Claustrum13.77 ± 0.25
Epithalamus13.28 ± 0.31
Frontal Lobe13.75 ± 0.3
Globus Pallidus13.37 ± 0.51
Hypothalamus14.15 ± 0.11
Insula13.87 ± 0.29
Limbic Lobe13.59 ± 0.5
Mesencephalon13.52 ± 0.36
Myelencephalon13.48 ± 0.45
Occipital Lobe13 ± 0.54
Parietal Lobe13.59 ± 0.37
Pontine Tegmentum13.6 ± 0.44
Striatum13.11 ± 0.51
Subthalamus14.11 ± 0.22
Temporal Lobe13.76 ± 0.31
Thalamus13.24 ± 0.32
White Matter12.81 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ngfrap1CBCerebellum100
100
Ngfrap1CTXCerebral cortex100
100
Ngfrap1HIPHippocampal region100
100
Ngfrap1HPFHippocampal formation100
100
Ngfrap1HYHypothalamus100
100
Ngfrap1LSXLateral septal complex100
100
Ngfrap1MBMidbrain100
100
Ngfrap1MYMedulla100
100
Ngfrap1OLFOlfactory bulb100
100
Ngfrap1PPons100
100
Ngfrap1PALPallidum100
100
Ngfrap1RHPRetrohippocampal region100
100
Ngfrap1sAMYStriatum-like amygdalar nuclei100
100
Ngfrap1STRStriatum98.62
85.35
Ngfrap1STRdStriatum dorsal region78.1
69.01
Ngfrap1STRvStriatum ventral region100
100
Ngfrap1THThalamus100
99.58
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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