AutismKB 2.0

Annotation Detail for NPTN


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Basic Information Top
Gene Symbol:NPTN ( DKFZp686L2477,GP55,GP65,MGC102805,SDFR1,SDR1,np55,np65 )
Gene Full Name: neuroplastin
Band: 15q24.1
Quick LinksEntrez ID:27020; OMIM: 612820; Uniprot ID:NPTN_HUMAN; ENSEMBL ID: ENSG00000156642; HGNC ID: 17867
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst6 / 6231996
fetus29 / 56401251
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult166 / 193912185
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor1 / 3436629
chondrosarcoma8 / 8282396
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor13 / 119369108
germ cell tumor10 / 26384537
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal222 / 336030766
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor21 / 90257232
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites3 / 4001574
bladder3 / 29757100
blood5 / 12347840
bone10 / 71655139
bone marrow0 / 488010 
brain75 / 110098968
cervix5 / 48171103
connective tissue5 / 14925533
ear3 / 16212185
embryonic tissue15 / 21572269
esophagus3 / 20209148
eye18 / 21105485
heart5 / 8962655
intestine18 / 23447276
kidney19 / 21177789
larynx0 / 241450 
liver4 / 20774319
lung38 / 336974112
lymph1 / 4427022
lymph node3 / 9161032
mammary gland13 / 15327184
mouth3 / 6705244
muscle6 / 10771555
nerve2 / 15768126
ovary0 / 1020510 
pancreas14 / 21481265
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland5 / 16585301
placenta23 / 28082581
prostate5 / 18934526
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach6 / 9661962
testis17 / 33044251
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus31 / 232878133
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202228_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts366
Adipocyte444.95
AdrenalCortex136.3
Adrenalgland373.3
Amygdala4969.3
Appendix231.45
AtrioventricularNode50.85
BDCA4+_DentriticCells592.25
Bonemarrow217.4
BronchialEpithelialCells1007.4
CD105+_Endothelial186.7
CD14+_Monocytes922.7
CD19+_BCells(neg._sel.)315.65
CD33+_Myeloid1696.95
CD34+326.55
CD4+_Tcells262.4
CD56+_NKCells786.85
CD71+_EarlyErythroid104.6
CD8+_Tcells352.9
CardiacMyocytes471.25
Caudatenucleus1898.6
Cerebellum1302.5
CerebellumPeduncles1274.65
CiliaryGanglion95.35
CingulateCortex1635.7
Colorectaladenocarcinoma272.75
DorsalRootGanglion129.45
FetalThyroid322.95
Fetalbrain1406.45
Fetalliver123.55
Fetallung514.1
GlobusPallidus786.7
Heart153.45
Hypothalamus1639.3
Kidney382.05
Leukemia_chronicMyelogenousK-56269.15
Leukemia_promyelocytic-HL-60167.75
Leukemialymphoblastic(MOLT-4)81.35
Liver53.1
Lung782
Lymphnode318.8
Lymphoma_burkitts(Daudi)133.25
Lymphoma_burkitts(Raji)91.6
MedullaOblongata1683.1
OccipitalLobe1857.6
OlfactoryBulb191.35
Ovary130.75
Pancreas261
PancreaticIslet535.95
ParietalLobe1424.85
Pituitary765.25
Placenta851.1
Pons887.9
PrefrontalCortex4715.55
Prostate1096.75
Salivarygland411.35
SkeletalMuscle8.1
Skin140.65
SmoothMuscle958.15
Spinalcord589.1
SubthalamicNucleus1423.7
SuperiorCervicalGanglion69.6
TemporalLobe1279.6
Testis502
TestisGermCell953.1
TestisIntersitial303.15
TestisLeydigCell280.05
TestisSeminiferousTubule176.55
Thalamus1423.6
Thymus146.9
Thyroid1643.35
Tongue155.7
Tonsil181.25
Trachea901
TrigeminalGanglion58.25
Uterus1742.05
UterusCorpus261.35
WholeBlood1268.2
Wholebrain3870.75
colon2151
pineal_day537.04
pineal_night652.64
retina1609.725
small_intestine2225.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P37598
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.36 ± 0.31
Basal Forebrain9.02 ± 0.26
Basal Part of Pons9.78 ± 0.17
Cerebellar Cortex9.13 ± 0.61
Cerebellar Nuclei9.18 ± 0.52
Claustrum9.59 ± 0.31
Epithalamus8.37 ± 0.44
Frontal Lobe9.33 ± 0.4
Globus Pallidus8.1 ± 0.66
Hypothalamus9.07 ± 0.25
Insula9.29 ± 0.22
Limbic Lobe9.38 ± 0.53
Mesencephalon9.18 ± 0.56
Myelencephalon9.19 ± 0.51
Occipital Lobe9.43 ± 0.55
Parietal Lobe9.34 ± 0.4
Pontine Tegmentum9.13 ± 0.3
Striatum9.43 ± 0.39
Subthalamus9.49 ± 0.33
Temporal Lobe9.42 ± 0.34
Thalamus9.24 ± 0.33
White Matter7.56 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NptnCBCerebellum38.05
100
NptnCTXCerebral cortex100
100
NptnHIPHippocampal region100
100
NptnHPFHippocampal formation100
100
NptnHYHypothalamus96.14
100
NptnLSXLateral septal complex100
100
NptnMBMidbrain100
100
NptnMYMedulla100
100
NptnOLFOlfactory bulb100
100
NptnPPons96.45
100
NptnPALPallidum94.04
100
NptnRHPRetrohippocampal region100
100
NptnsAMYStriatum-like amygdalar nuclei100
100
NptnSTRStriatum100
100
NptnSTRdStriatum dorsal region100
100
NptnSTRvStriatum ventral region100
100
NptnTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000282 18 210 227 AEDSGEYHCVYHFVSAPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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