AutismKB 2.0

Annotation Detail for D4S234E


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Basic Information Top
Gene Symbol:D4S234E ( D4S234,NEEP21,NSG1,P21 )
Gene Full Name: -
Band: 4p16.3
Quick LinksEntrez ID:27065; OMIM: 607645; Uniprot ID:NSG1_HUMAN; ENSEMBL ID: ENSG00000168824; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst2 / 6231932
fetus289 / 564012512
neonate1 / 3109732
infant0 / 236200 
juvenile6 / 55556107
adult176 / 193912190
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor89 / 263845337
glioma10 / 10688393
head and neck tumor0 / 1363020 
kidney tumor26 / 68959377
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal709 / 3360307210
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS26 / 125680206
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor12 / 12494996
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain566 / 1100989514
cervix1 / 4817120
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye26 / 211054123
heart5 / 8962655
intestine6 / 23447225
kidney29 / 211777136
larynx0 / 241450 
liver3 / 20774314
lung20 / 33697459
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary5 / 10205148
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland7 / 16585422
placenta35 / 280825124
prostate9 / 18934547
salivary gland0 / 201550 
skin27 / 210574128
spleen1 / 5395218
stomach2 / 9661920
testis29 / 33044287
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus4 / 23287817
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209569_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.35
Adipocyte4.6
AdrenalCortex5.15
Adrenalgland5.65
Amygdala26.75
Appendix7.15
AtrioventricularNode6.35
BDCA4+_DentriticCells5.35
Bonemarrow6.9
BronchialEpithelialCells17.55
CD105+_Endothelial3.75
CD14+_Monocytes3.95
CD19+_BCells(neg._sel.)5.1
CD33+_Myeloid5.1
CD34+4.5
CD4+_Tcells53.75
CD56+_NKCells7.2
CD71+_EarlyErythroid3.6
CD8+_Tcells64.6
CardiacMyocytes13.3
Caudatenucleus76.75
Cerebellum214.6
CerebellumPeduncles134.35
CiliaryGanglion8.9
CingulateCortex12.9
Colorectaladenocarcinoma4.75
DorsalRootGanglion8.4
FetalThyroid6.35
Fetalbrain206.75
Fetalliver3.55
Fetallung8.95
GlobusPallidus23.15
Heart8
Hypothalamus183.8
Kidney4.8
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)5.4
Liver6.55
Lung6.3
Lymphnode5.45
Lymphoma_burkitts(Daudi)5.95
Lymphoma_burkitts(Raji)9.15
MedullaOblongata38.95
OccipitalLobe39.1
OlfactoryBulb5
Ovary14.75
Pancreas4.1
PancreaticIslet6.2
ParietalLobe45.45
Pituitary487
Placenta466.4
Pons48.95
PrefrontalCortex18.7
Prostate25.55
Salivarygland5.65
SkeletalMuscle5.65
Skin33.05
SmoothMuscle8.15
Spinalcord24.05
SubthalamicNucleus12.05
SuperiorCervicalGanglion23.7
TemporalLobe23.35
Testis19.6
TestisGermCell40.25
TestisIntersitial27.7
TestisLeydigCell7.4
TestisSeminiferousTubule9.3
Thalamus72
Thymus15.6
Thyroid7.3
Tongue12.4
Tonsil6.25
Trachea7.15
TrigeminalGanglion7.8
Uterus4.6
UterusCorpus11.1
WholeBlood11.6
Wholebrain136.15
colon5.45
pineal_day4.92
pineal_night5.54
retina18.475
small_intestine6.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_732_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.75 ± 0.53
Basal Forebrain7.82 ± 0.41
Basal Part of Pons7.92 ± 0.34
Cerebellar Cortex8.07 ± 0.33
Cerebellar Nuclei8.44 ± 0.32
Claustrum6.87 ± 0.78
Epithalamus6.94 ± 1.21
Frontal Lobe7.72 ± 0.54
Globus Pallidus6.66 ± 0.61
Hypothalamus8.6 ± 0.29
Insula7.62 ± 0.27
Limbic Lobe6.73 ± 0.68
Mesencephalon7.59 ± 0.6
Myelencephalon7.33 ± 0.84
Occipital Lobe6.5 ± 0.91
Parietal Lobe7.48 ± 0.72
Pontine Tegmentum7.57 ± 0.59
Striatum7.21 ± 0.73
Subthalamus8.52 ± 0.43
Temporal Lobe7.4 ± 0.55
Thalamus7.61 ± 0.41
White Matter4.31 ± 0.72
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nsg1CBCerebellum81.68
100
Nsg1CTXCerebral cortex100
100
Nsg1HIPHippocampal region100
100
Nsg1HPFHippocampal formation100
100
Nsg1HYHypothalamus100
100
Nsg1LSXLateral septal complex100
100
Nsg1MBMidbrain100
100
Nsg1MYMedulla100
100
Nsg1OLFOlfactory bulb100
100
Nsg1PPons100
100
Nsg1PALPallidum100
100
Nsg1RHPRetrohippocampal region100
100
Nsg1sAMYStriatum-like amygdalar nuclei100
100
Nsg1STRStriatum100
100
Nsg1STRdStriatum dorsal region100
100
Nsg1STRvStriatum ventral region100
100
Nsg1THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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