AutismKB 2.0

Annotation Detail for DAPP1


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Basic Information Top
Gene Symbol:DAPP1 ( BAM32,DKFZp667E0716 )
Gene Full Name: dual adaptor of phosphotyrosine and 3-phosphoinositides
Band: 4q23
Quick LinksEntrez ID:27071; OMIM: 605768; Uniprot ID:DAPP1_HUMAN; ENSEMBL ID: ENSG00000070190; HGNC ID: 16500
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal72 / 336030721
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood5 / 12347840
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye0 / 2110540 
heart1 / 8962611
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph2 / 4427045
lymph node17 / 91610185
mammary gland6 / 15327139
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx9 / 41328217
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil5 / 16999294
trachea3 / 5241357
umbilical cord0 / 136800 
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_747_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.4 ± 1.04
Basal Forebrain2.25 ± 0.78
Basal Part of Pons1.61 ± 0.38
Cerebellar Cortex1.77 ± 0.76
Cerebellar Nuclei2.26 ± 0.71
Claustrum3 ± 0.82
Epithalamus1.72 ± 0.74
Frontal Lobe1.83 ± 0.76
Globus Pallidus2.82 ± 0.48
Hypothalamus1.98 ± 0.66
Insula1.75 ± 0.52
Limbic Lobe1.89 ± 0.61
Mesencephalon2.09 ± 0.67
Myelencephalon1.95 ± 0.68
Occipital Lobe1.98 ± 0.65
Parietal Lobe1.99 ± 0.71
Pontine Tegmentum1.98 ± 0.68
Striatum2.07 ± 0.5
Subthalamus2.13 ± 0.71
Temporal Lobe1.83 ± 0.68
Thalamus1.9 ± 0.59
White Matter2.32 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dapp1CBCerebellum6.67
8.81
Dapp1CTXCerebral cortex7.88
6.93
Dapp1HIPHippocampal region7.34
8.26
Dapp1HPFHippocampal formation6.33
6.58
Dapp1HYHypothalamus0.62
1.1
Dapp1LSXLateral septal complex6.92
6.61
Dapp1MBMidbrain2.3
4.11
Dapp1MYMedulla1.53
2.12
Dapp1OLFOlfactory bulb16.34
14.21
Dapp1PPons1.32
2.36
Dapp1PALPallidum1.44
1.69
Dapp1RHPRetrohippocampal region4.54
4.05
Dapp1sAMYStriatum-like amygdalar nuclei1.34
1.58
Dapp1STRStriatum2.51
2.49
Dapp1STRdStriatum dorsal region1.53
1.68
Dapp1STRvStriatum ventral region3.24
2.56
Dapp1THThalamus3.14
4.14
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018