AutismKB 2.0

Annotation Detail for KCNMB3


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Basic Information Top
Gene Symbol:KCNMB3 ( BKBETA3,HBETA3,KCNMB2,KCNMBL,SLOBETA3 )
Gene Full Name: potassium large conductance calcium-activated channel, subfamily M beta member 3
Band: 3q26.32
Quick LinksEntrez ID:27094; OMIM: 605222; Uniprot ID:KCMB3_HUMAN; ENSEMBL ID: ENSG00000171121; HGNC ID: 6287
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult5 / 19391212
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal13 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221125_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7
Adipocyte5.7
AdrenalCortex6
Adrenalgland4.9
Amygdala6.05
Appendix6.3
AtrioventricularNode4.65
BDCA4+_DentriticCells6.35
Bonemarrow6.15
BronchialEpithelialCells5.55
CD105+_Endothelial5.75
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)6.2
CD33+_Myeloid7.45
CD34+7.2
CD4+_Tcells6.3
CD56+_NKCells6.9
CD71+_EarlyErythroid5.4
CD8+_Tcells5.6
CardiacMyocytes7.25
Caudatenucleus5.15
Cerebellum4.65
CerebellumPeduncles6.5
CiliaryGanglion4.05
CingulateCortex5.85
Colorectaladenocarcinoma5.8
DorsalRootGanglion4.4
FetalThyroid5.8
Fetalbrain5.7
Fetalliver5
Fetallung4.85
GlobusPallidus4.4
Heart7.6
Hypothalamus6
Kidney4.65
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-605.05
Leukemialymphoblastic(MOLT-4)4.55
Liver8.1
Lung6.35
Lymphnode5
Lymphoma_burkitts(Daudi)7.35
Lymphoma_burkitts(Raji)8.05
MedullaOblongata5.3
OccipitalLobe5.05
OlfactoryBulb4.55
Ovary3.85
Pancreas5.8
PancreaticIslet6.3
ParietalLobe6.05
Pituitary6.8
Placenta5.95
Pons5.45
PrefrontalCortex7.15
Prostate6.8
Salivarygland4.7
SkeletalMuscle6.7
Skin4.5
SmoothMuscle6.55
Spinalcord6.15
SubthalamicNucleus5.7
SuperiorCervicalGanglion9.25
TemporalLobe5.25
Testis5.15
TestisGermCell4.95
TestisIntersitial7.3
TestisLeydigCell5.7
TestisSeminiferousTubule5.65
Thalamus5.85
Thymus4.55
Thyroid7.25
Tongue5.65
Tonsil5.65
Trachea4.8
TrigeminalGanglion5.65
Uterus4.75
UterusCorpus6
WholeBlood6.3
Wholebrain4.85
colon5.85
pineal_day7.06
pineal_night6.9
retina6.95
small_intestine5.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P251661
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.46 ± 0.83
Basal Forebrain3.49 ± 0.4
Basal Part of Pons2.87 ± 0.37
Cerebellar Cortex3.07 ± 0.64
Cerebellar Nuclei3.65 ± 0.7
Claustrum3.63 ± 0.55
Epithalamus3.15 ± 0.78
Frontal Lobe3.21 ± 0.61
Globus Pallidus3.98 ± 0.38
Hypothalamus3.17 ± 0.69
Insula2.88 ± 0.67
Limbic Lobe3.05 ± 0.72
Mesencephalon3.4 ± 0.73
Myelencephalon3.3 ± 0.73
Occipital Lobe3.72 ± 0.57
Parietal Lobe3.33 ± 0.82
Pontine Tegmentum3.34 ± 0.66
Striatum3.25 ± 0.78
Subthalamus3.56 ± 0.41
Temporal Lobe3.26 ± 0.65
Thalamus3.19 ± 0.67
White Matter4.51 ± 0.22
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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