AutismKB 2.0

Annotation Detail for INPP5J


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:INPP5J ( INPP5,MGC129984,PIB5PA,PIPP )
Gene Full Name: inositol polyphosphate-5-phosphatase J
Band: 22q12.2
Quick LinksEntrez ID:27124; OMIM: 606481; Uniprot ID:PI5PA_HUMAN; ENSEMBL ID: ENSG00000185133; HGNC ID: 8956
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor16 / 136302117
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal90 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS31 / 125680246
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain58 / 110098952
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye7 / 21105433
heart2 / 8962622
intestine2 / 2344728
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid16 / 47473337
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213651_at
Cell line Expression level Expression bar
721_B_lymphoblasts3.95
Adipocyte3.1
AdrenalCortex3.25
Adrenalgland2.65
Amygdala3.4
Appendix3.1
AtrioventricularNode2.5
BDCA4+_DentriticCells3.5
Bonemarrow3.1
BronchialEpithelialCells3.1
CD105+_Endothelial3.15
CD14+_Monocytes3.4
CD19+_BCells(neg._sel.)3.35
CD33+_Myeloid4.05
CD34+4
CD4+_Tcells3.45
CD56+_NKCells3.8
CD71+_EarlyErythroid2.95
CD8+_Tcells3.05
CardiacMyocytes3.95
Caudatenucleus2.8
Cerebellum2.55
CerebellumPeduncles7.5
CiliaryGanglion2.65
CingulateCortex3.3
Colorectaladenocarcinoma3.2
DorsalRootGanglion2.4
FetalThyroid32.45
Fetalbrain3.15
Fetalliver2.7
Fetallung2.65
GlobusPallidus2.4
Heart4.9
Hypothalamus3.55
Kidney2.75
Leukemia_chronicMyelogenousK-5622.85
Leukemia_promyelocytic-HL-602.8
Leukemialymphoblastic(MOLT-4)2.55
Liver4.3
Lung3.5
Lymphnode2.7
Lymphoma_burkitts(Daudi)4
Lymphoma_burkitts(Raji)4.4
MedullaOblongata2.95
OccipitalLobe2.85
OlfactoryBulb2.5
Ovary2.05
Pancreas2.8
PancreaticIslet3.4
ParietalLobe3.3
Pituitary3.7
Placenta3.3
Pons3.05
PrefrontalCortex4
Prostate3.75
Salivarygland2.5
SkeletalMuscle3.75
Skin2.4
SmoothMuscle3.6
Spinalcord3.35
SubthalamicNucleus2.85
SuperiorCervicalGanglion3.45
TemporalLobe2.9
Testis2.75
TestisGermCell2.65
TestisIntersitial2.65
TestisLeydigCell3.1
TestisSeminiferousTubule2.7
Thalamus3.2
Thymus2.5
Thyroid554.35
Tongue3.5
Tonsil3.05
Trachea2.65
TrigeminalGanglion3.2
Uterus2.65
UterusCorpus2.8
WholeBlood3.5
Wholebrain2.75
colon3.2
pineal_day3.98
pineal_night3.88
retina3.875
small_intestine3.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7979_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.26 ± 0.83
Basal Forebrain3.44 ± 0.36
Basal Part of Pons4.59 ± 0.96
Cerebellar Cortex5.04 ± 0.38
Cerebellar Nuclei4.59 ± 0.6
Claustrum4.06 ± 0.85
Epithalamus3.37 ± 0.82
Frontal Lobe4.5 ± 0.61
Globus Pallidus3.63 ± 0.66
Hypothalamus3.28 ± 0.66
Insula4.44 ± 0.65
Limbic Lobe4.59 ± 0.86
Mesencephalon4.17 ± 0.95
Myelencephalon4.16 ± 0.83
Occipital Lobe3.66 ± 0.92
Parietal Lobe4.4 ± 0.73
Pontine Tegmentum4.2 ± 0.74
Striatum2.94 ± 0.72
Subthalamus4.92 ± 0.98
Temporal Lobe4.42 ± 0.56
Thalamus4.22 ± 0.81
White Matter1.78 ± 0.77
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pib5paCBCerebellum85.76
100
Pib5paCTXCerebral cortex48.09
46.65
Pib5paHIPHippocampal region71.06
100
Pib5paHPFHippocampal formation61.06
86.01
Pib5paHYHypothalamus18.83
18.46
Pib5paLSXLateral septal complex15.19
10.65
Pib5paMBMidbrain38.22
43.09
Pib5paMYMedulla60.75
88.69
Pib5paOLFOlfactory bulb100
100
Pib5paPPons53.74
72.71
Pib5paPALPallidum38.48
43.72
Pib5paRHPRetrohippocampal region48.2
47.76
Pib5pasAMYStriatum-like amygdalar nuclei19.21
18.08
Pib5paSTRStriatum71.27
57.35
Pib5paSTRdStriatum dorsal region86.41
69.7
Pib5paSTRvStriatum ventral region64.82
50.95
Pib5paTHThalamus94.45
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved