AutismKB 2.0

Annotation Detail for SNX5


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Basic Information Top
Gene Symbol:SNX5 ( FLJ10931 )
Gene Full Name: sorting nexin 5
Band: 20p11.23
Quick LinksEntrez ID:27131; OMIM: 605937; Uniprot ID:SNX5_HUMAN; ENSEMBL ID: ENSG00000089006; HGNC ID: 14969
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst17 / 62319272
fetus65 / 564012115
neonate13 / 31097418
infant1 / 2362042
juvenile3 / 5555653
adult269 / 1939121138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma2 / 17475114
breast (mammary gland) tumor15 / 94178159
cervical tumor6 / 34366174
chondrosarcoma17 / 82823205
colorectal tumor18 / 114246157
esophageal tumor2 / 17290115
gastrointestinal tumor21 / 119369175
germ cell tumor65 / 263845246
glioma13 / 106883121
head and neck tumor24 / 136302176
kidney tumor1 / 6895914
leukemia10 / 95842104
liver tumor29 / 96359300
lung tumor11 / 103127106
lymphoma14 / 71755195
non-neoplasia10 / 97250102
normal426 / 3360307126
ovarian tumor22 / 76682286
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor20 / 124949160
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland8 / 33197240
ascites7 / 40015174
bladder3 / 29757100
blood18 / 123478145
bone11 / 71655153
bone marrow7 / 48801143
brain91 / 110098982
cervix6 / 48171124
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue39 / 215722180
esophagus2 / 2020998
eye24 / 211054113
heart10 / 89626111
intestine41 / 234472174
kidney31 / 211777146
larynx6 / 24145248
liver38 / 207743182
lung39 / 336974115
lymph7 / 44270158
lymph node25 / 91610272
mammary gland18 / 153271117
mouth7 / 67052104
muscle18 / 107715167
nerve3 / 15768190
ovary24 / 102051235
pancreas21 / 21481297
parathyroid11 / 20539535
pharynx7 / 41328169
pituitary gland0 / 165850 
placenta81 / 280825288
prostate15 / 18934579
salivary gland3 / 20155148
skin36 / 210574170
spleen9 / 53952166
stomach22 / 96619227
testis28 / 33044284
thymus8 / 8113198
thyroid8 / 47473168
tonsil3 / 16999176
trachea5 / 5241395
umbilical cord2 / 13680146
uterus28 / 232878120
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217792_at
Cell line Expression level Expression bar
721_B_lymphoblasts890.8
Adipocyte96.5
AdrenalCortex98.1
Adrenalgland57.5
Amygdala95.9
Appendix45.5
AtrioventricularNode26.05
BDCA4+_DentriticCells360.55
Bonemarrow58.1
BronchialEpithelialCells66.4
CD105+_Endothelial207.2
CD14+_Monocytes273.6
CD19+_BCells(neg._sel.)334.4
CD33+_Myeloid144.5
CD34+601.85
CD4+_Tcells79.5
CD56+_NKCells189.55
CD71+_EarlyErythroid46.45
CD8+_Tcells83.15
CardiacMyocytes45.3
Caudatenucleus81
Cerebellum41.95
CerebellumPeduncles56.75
CiliaryGanglion38.85
CingulateCortex71.85
Colorectaladenocarcinoma48.8
DorsalRootGanglion25.95
FetalThyroid178.95
Fetalbrain43.3
Fetalliver140
Fetallung160.25
GlobusPallidus81.4
Heart32.4
Hypothalamus177.1
Kidney90.25
Leukemia_chronicMyelogenousK-56275.3
Leukemia_promyelocytic-HL-60144.7
Leukemialymphoblastic(MOLT-4)129.65
Liver56.55
Lung85.35
Lymphnode143.8
Lymphoma_burkitts(Daudi)268.7
Lymphoma_burkitts(Raji)95.35
MedullaOblongata52.45
OccipitalLobe88.5
OlfactoryBulb113.05
Ovary38.75
Pancreas40.65
PancreaticIslet45.2
ParietalLobe69.1
Pituitary84.5
Placenta70.2
Pons44.4
PrefrontalCortex118.1
Prostate73.95
Salivarygland55.9
SkeletalMuscle45.8
Skin38.9
SmoothMuscle64.65
Spinalcord196
SubthalamicNucleus71.2
SuperiorCervicalGanglion23.4
TemporalLobe35.25
Testis45.3
TestisGermCell54.15
TestisIntersitial20.45
TestisLeydigCell56.8
TestisSeminiferousTubule47.15
Thalamus98.6
Thymus71.7
Thyroid661.75
Tongue48.6
Tonsil110.3
Trachea58.5
TrigeminalGanglion28.85
Uterus89.1
UterusCorpus32.4
WholeBlood94.6
Wholebrain59.5
colon95.2
pineal_day179.5
pineal_night137.5
retina121.4
small_intestine90.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_3675_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.42 ± 0.33
Basal Forebrain7.58 ± 0.14
Basal Part of Pons7.09 ± 0.21
Cerebellar Cortex7.23 ± 0.23
Cerebellar Nuclei7.53 ± 0.26
Claustrum7.35 ± 0.29
Epithalamus7.67 ± 0.26
Frontal Lobe7.34 ± 0.32
Globus Pallidus8.24 ± 0.28
Hypothalamus7.48 ± 0.3
Insula7.39 ± 0.27
Limbic Lobe7.21 ± 0.31
Mesencephalon7.55 ± 0.31
Myelencephalon7.4 ± 0.34
Occipital Lobe7.41 ± 0.3
Parietal Lobe7.42 ± 0.33
Pontine Tegmentum7.46 ± 0.3
Striatum7.54 ± 0.39
Subthalamus7.53 ± 0.02
Temporal Lobe7.26 ± 0.28
Thalamus7.52 ± 0.28
White Matter8.53 ± 0.23
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000247 24 241 264 ADDYIHTAACLHSLALEEPTVIKK Peptide Atlas
SNX5_HUMAN_2 14 2 15 AAVPELLQQQEEDR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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