AutismKB 2.0

Annotation Detail for GPKOW


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Basic Information Top
Gene Symbol:GPKOW ( GPATC5,GPATCH5,Spp2,T54 )
Gene Full Name: G patch domain and KOW motifs
Band: Xp11.23
Quick LinksEntrez ID:27238; OMIM: NA; Uniprot ID:GPKOW_HUMAN; ENSEMBL ID: ENSG00000068394; HGNC ID: 30677
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst9 / 62319144
fetus17 / 56401230
neonate0 / 310970 
infant3 / 23620127
juvenile3 / 5555653
adult100 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor12 / 119369100
germ cell tumor14 / 26384553
glioma3 / 10688328
head and neck tumor9 / 13630266
kidney tumor3 / 6895943
leukemia7 / 9584273
liver tumor2 / 9635920
lung tumor12 / 103127116
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal120 / 336030735
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites7 / 40015174
bladder0 / 297570 
blood16 / 123478129
bone5 / 7165569
bone marrow0 / 488010 
brain28 / 110098925
cervix9 / 48171186
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine12 / 23447251
kidney5 / 21177723
larynx1 / 2414541
liver9 / 20774343
lung21 / 33697462
lymph1 / 4427022
lymph node2 / 9161021
mammary gland7 / 15327145
mouth6 / 6705289
muscle0 / 1077150 
nerve2 / 15768126
ovary4 / 10205139
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta22 / 28082578
prostate5 / 18934526
salivary gland1 / 2015549
skin10 / 21057447
spleen3 / 5395255
stomach1 / 9661910
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203776_at
Cell line Expression level Expression bar
721_B_lymphoblasts25.3
Adipocyte4.75
AdrenalCortex5.3
Adrenalgland4.45
Amygdala7.15
Appendix5.2
AtrioventricularNode3.55
BDCA4+_DentriticCells16.2
Bonemarrow5.1
BronchialEpithelialCells5.8
CD105+_Endothelial24.2
CD14+_Monocytes12.65
CD19+_BCells(neg._sel.)10.2
CD33+_Myeloid12.8
CD34+11.65
CD4+_Tcells19.8
CD56+_NKCells26.15
CD71+_EarlyErythroid35.55
CD8+_Tcells10.7
CardiacMyocytes9.65
Caudatenucleus4.75
Cerebellum5.4
CerebellumPeduncles8.55
CiliaryGanglion3.35
CingulateCortex5.3
Colorectaladenocarcinoma8.75
DorsalRootGanglion3.5
FetalThyroid5.65
Fetalbrain6.3
Fetalliver4.4
Fetallung4.35
GlobusPallidus3.85
Heart6.75
Hypothalamus11.5
Kidney4
Leukemia_chronicMyelogenousK-5624.8
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)4.8
Liver6.7
Lung8
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.5
Lymphoma_burkitts(Raji)7.3
MedullaOblongata4.75
OccipitalLobe5.1
OlfactoryBulb4.1
Ovary3.4
Pancreas4.05
PancreaticIslet7
ParietalLobe5.45
Pituitary6.05
Placenta6.15
Pons5.2
PrefrontalCortex6.55
Prostate6.05
Salivarygland3.55
SkeletalMuscle5.45
Skin3.65
SmoothMuscle6.7
Spinalcord7.35
SubthalamicNucleus4.65
SuperiorCervicalGanglion5.85
TemporalLobe4.9
Testis4.4
TestisGermCell3.9
TestisIntersitial4.05
TestisLeydigCell5.05
TestisSeminiferousTubule4.45
Thalamus9.95
Thymus5
Thyroid7
Tongue5.1
Tonsil5.1
Trachea4
TrigeminalGanglion5.25
Uterus4.15
UterusCorpus4.65
WholeBlood8.3
Wholebrain10.3
colon5.3
pineal_day15.86
pineal_night11.22
retina7.775
small_intestine4.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10563_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.49 ± 0.6
Basal Forebrain6.05 ± 0.18
Basal Part of Pons6.2 ± 0.59
Cerebellar Cortex6.21 ± 0.47
Cerebellar Nuclei5.7 ± 0.56
Claustrum5.6 ± 0.91
Epithalamus6.41 ± 0.46
Frontal Lobe6.18 ± 0.46
Globus Pallidus6.17 ± 0.17
Hypothalamus6.4 ± 0.42
Insula6.23 ± 0.26
Limbic Lobe5.7 ± 0.54
Mesencephalon5.94 ± 0.45
Myelencephalon5.93 ± 0.56
Occipital Lobe5.34 ± 0.52
Parietal Lobe5.92 ± 0.45
Pontine Tegmentum5.94 ± 0.46
Striatum5.46 ± 0.38
Subthalamus5.98 ± 0.54
Temporal Lobe6.17 ± 0.41
Thalamus6.03 ± 0.42
White Matter6.67 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
GpkowCBCerebellum5.05
5.54
GpkowCTXCerebral cortex3.64
2.68
GpkowHIPHippocampal region7.62
7.05
GpkowHPFHippocampal formation8.07
6.97
GpkowHYHypothalamus0.15
0.14
GpkowLSXLateral septal complex1.08
1.03
GpkowMBMidbrain1.31
1.35
GpkowMYMedulla2.79
2.83
GpkowOLFOlfactory bulb3.84
2.9
GpkowPPons1.39
1.54
GpkowPALPallidum1.34
1.34
GpkowRHPRetrohippocampal region9.24
7.15
GpkowsAMYStriatum-like amygdalar nuclei0.78
0.47
GpkowSTRStriatum0.75
0.65
GpkowSTRdStriatum dorsal region0.85
0.77
GpkowSTRvStriatum ventral region0.24
0.29
GpkowTHThalamus1.87
1.93
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00066131 20 6 25 EGVLPLTAASTAPISFGFTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018