AutismKB 2.0

Annotation Detail for CNTN6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CNTN6 ( MGC133256,NB3 )
Gene Full Name: contactin 6
Band: 3p26.3
Quick LinksEntrez ID:27255; OMIM: 607220; Uniprot ID:CNTN6_HUMAN; ENSEMBL ID: ENSG00000134115; HGNC ID: 2176
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal58 / 336030717
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain42 / 110098938
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207195_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.9
Adipocyte8.65
AdrenalCortex14.65
Adrenalgland8.85
Amygdala8.6
Appendix12.85
AtrioventricularNode14.65
BDCA4+_DentriticCells8.05
Bonemarrow9.4
BronchialEpithelialCells8
CD105+_Endothelial8.3
CD14+_Monocytes9.25
CD19+_BCells(neg._sel.)11.4
CD33+_Myeloid9.95
CD34+9.7
CD4+_Tcells9
CD56+_NKCells9.4
CD71+_EarlyErythroid8.35
CD8+_Tcells7.3
CardiacMyocytes13.75
Caudatenucleus7.8
Cerebellum7.3
CerebellumPeduncles14
CiliaryGanglion10.7
CingulateCortex9.85
Colorectaladenocarcinoma8.45
DorsalRootGanglion12.35
FetalThyroid13
Fetalbrain8.45
Fetalliver7.45
Fetallung6.8
GlobusPallidus7.6
Heart16.3
Hypothalamus9.2
Kidney8.4
Leukemia_chronicMyelogenousK-5627.8
Leukemia_promyelocytic-HL-608.6
Leukemialymphoblastic(MOLT-4)6.2
Liver13.65
Lung9.5
Lymphnode8.35
Lymphoma_burkitts(Daudi)11.65
Lymphoma_burkitts(Raji)13.4
MedullaOblongata7.95
OccipitalLobe7.85
OlfactoryBulb6.95
Ovary7.35
Pancreas7.25
PancreaticIslet9.5
ParietalLobe10.2
Pituitary10.3
Placenta8.45
Pons11.05
PrefrontalCortex10.45
Prostate9.95
Salivarygland7.5
SkeletalMuscle12.15
Skin9.1
SmoothMuscle9.8
Spinalcord9.3
SubthalamicNucleus9.5
SuperiorCervicalGanglion23.2
TemporalLobe8.65
Testis7.25
TestisGermCell6.7
TestisIntersitial7.5
TestisLeydigCell9.35
TestisSeminiferousTubule7.55
Thalamus11.45
Thymus6.25
Thyroid10.65
Tongue13.15
Tonsil9.2
Trachea7.1
TrigeminalGanglion12.75
Uterus6.5
UterusCorpus11.05
WholeBlood9.05
Wholebrain6.7
colon8.4
pineal_day10.2
pineal_night9.98
retina11.075
small_intestine7.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10052_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.72 ± 0.91
Basal Forebrain6.8 ± 0.32
Basal Part of Pons7.4 ± 0.52
Cerebellar Cortex7.98 ± 0.32
Cerebellar Nuclei7.19 ± 0.38
Claustrum8.47 ± 0.6
Epithalamus6.14 ± 1.44
Frontal Lobe7.85 ± 0.67
Globus Pallidus6.39 ± 0.39
Hypothalamus7.18 ± 0.69
Insula7.31 ± 0.45
Limbic Lobe6.77 ± 1.07
Mesencephalon7.32 ± 0.84
Myelencephalon7.12 ± 0.91
Occipital Lobe6.06 ± 0.8
Parietal Lobe6.96 ± 0.44
Pontine Tegmentum7.17 ± 0.87
Striatum4.92 ± 0.64
Subthalamus7.42 ± 0.47
Temporal Lobe6.9 ± 0.42
Thalamus7.83 ± 0.56
White Matter4.66 ± 0.89
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cntn6CBCerebellum40.47
43.27
Cntn6CTXCerebral cortex38.14
21.95
Cntn6HIPHippocampal region11.07
9.19
Cntn6HPFHippocampal formation16.85
11.29
Cntn6HYHypothalamus24.08
13.16
Cntn6LSXLateral septal complex10.57
5.07
Cntn6MBMidbrain28.51
19.99
Cntn6MYMedulla28.11
22.67
Cntn6OLFOlfactory bulb39.82
26.11
Cntn6PPons21.11
17.34
Cntn6PALPallidum11.57
7.56
Cntn6RHPRetrohippocampal region24.64
13.86
Cntn6sAMYStriatum-like amygdalar nuclei11.84
5.23
Cntn6STRStriatum7.6
4.3
Cntn6STRdStriatum dorsal region5.48
3.14
Cntn6STRvStriatum ventral region12.03
7.54
Cntn6THThalamus38.36
21.49
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CNTN6_HUMAN_392 11 392 402 YQIIYANAELR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved