AutismKB 2.0

Annotation Detail for HPGDS


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HPGDS ( GSTS,PGDS )
Gene Full Name: hematopoietic prostaglandin D synthase
Band: 4q22.3
Quick LinksEntrez ID:27306; OMIM: 602598; Uniprot ID:HPGDS_HUMAN; ENSEMBL ID: ENSG00000163106; HGNC ID: 17890
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal24 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta12 / 28082542
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206726_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.7
Adipocyte6.2
AdrenalCortex6.55
Adrenalgland5.2
Amygdala7.4
Appendix6.45
AtrioventricularNode4.85
BDCA4+_DentriticCells5.95
Bonemarrow6.25
BronchialEpithelialCells5.85
CD105+_Endothelial5.65
CD14+_Monocytes6.05
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7
CD34+41.35
CD4+_Tcells6.1
CD56+_NKCells6.5
CD71+_EarlyErythroid5.55
CD8+_Tcells5.45
CardiacMyocytes10.7
Caudatenucleus5.45
Cerebellum6
CerebellumPeduncles7.9
CiliaryGanglion4.8
CingulateCortex6.15
Colorectaladenocarcinoma6
DorsalRootGanglion4.75
FetalThyroid5.9
Fetalbrain6
Fetalliver7.45
Fetallung4.7
GlobusPallidus4.35
Heart9.65
Hypothalamus6.35
Kidney6.8
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-605.25
Leukemialymphoblastic(MOLT-4)4.75
Liver8.8
Lung10.05
Lymphnode6.1
Lymphoma_burkitts(Daudi)7.9
Lymphoma_burkitts(Raji)12.2
MedullaOblongata6.35
OccipitalLobe5.3
OlfactoryBulb4.95
Ovary4.8
Pancreas4.85
PancreaticIslet6.4
ParietalLobe7.3
Pituitary7.1
Placenta15.35
Pons14.6
PrefrontalCortex7.1
Prostate9.7
Salivarygland4.95
SkeletalMuscle7.5
Skin5.05
SmoothMuscle6.7
Spinalcord8.35
SubthalamicNucleus5.6
SuperiorCervicalGanglion8
TemporalLobe6.35
Testis5.15
TestisGermCell4.95
TestisIntersitial4.95
TestisLeydigCell7.4
TestisSeminiferousTubule5.05
Thalamus6
Thymus4.75
Thyroid7.4
Tongue8.9
Tonsil5.9
Trachea6.45
TrigeminalGanglion7.75
Uterus6.45
UterusCorpus9.2
WholeBlood6.45
Wholebrain5.3
colon6.1
pineal_day7.16
pineal_night7.18
retina8.1
small_intestine7.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14502_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.43 ± 1.15
Basal Forebrain2.95 ± 0.73
Basal Part of Pons3.11 ± 0.6
Cerebellar Cortex2.68 ± 0.66
Cerebellar Nuclei3.65 ± 0.61
Claustrum3.75 ± 1.06
Epithalamus3.29 ± 1.12
Frontal Lobe3.01 ± 0.93
Globus Pallidus4.21 ± 0.69
Hypothalamus3.11 ± 1.09
Insula3.03 ± 0.6
Limbic Lobe3.1 ± 0.82
Mesencephalon3.11 ± 0.78
Myelencephalon3.19 ± 0.8
Occipital Lobe2.95 ± 0.88
Parietal Lobe3.15 ± 0.83
Pontine Tegmentum3.22 ± 0.82
Striatum3.41 ± 0.82
Subthalamus3.27 ± 0.69
Temporal Lobe3.08 ± 0.79
Thalamus3.15 ± 0.85
White Matter4.05 ± 1.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ptgds2CBCerebellum10.07
9.94
Ptgds2CTXCerebral cortex27.07
18.33
Ptgds2HIPHippocampal region12.21
11.16
Ptgds2HPFHippocampal formation14.4
12.1
Ptgds2HYHypothalamus3.11
2.48
Ptgds2LSXLateral septal complex2.19
1.32
Ptgds2MBMidbrain1.98
1.88
Ptgds2MYMedulla5.23
5.89
Ptgds2OLFOlfactory bulb25.12
17.78
Ptgds2PPons2.73
3.13
Ptgds2PALPallidum2.95
2.61
Ptgds2RHPRetrohippocampal region16.89
12.55
Ptgds2sAMYStriatum-like amygdalar nuclei2.35
1.6
Ptgds2STRStriatum4.9
3.23
Ptgds2STRdStriatum dorsal region5.31
3.52
Ptgds2STRvStriatum ventral region5.57
3.53
Ptgds2THThalamus3.77
2.89
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved