AutismKB 2.0

Annotation Detail for TNRC6A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TNRC6A ( CAGH26,DKFZp666E117,FLJ22043,GW1,GW182,KIAA1460,MGC75384,TNRC6 )
Gene Full Name: trinucleotide repeat containing 6A
Band: 16p12.1
Quick LinksEntrez ID:27327; OMIM: 610739; Uniprot ID:TNR6A_HUMAN; ENSEMBL ID: ENSG00000090905; HGNC ID: 11969
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst7 / 62319112
fetus35 / 56401262
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma15 / 82823181
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor15 / 136302110
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal164 / 336030748
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone4 / 7165555
bone marrow0 / 488010 
brain47 / 110098942
cervix1 / 4817120
connective tissue13 / 14925587
ear1 / 1621261
embryonic tissue20 / 21572292
esophagus0 / 202090 
eye7 / 21105433
heart6 / 8962666
intestine13 / 23447255
kidney14 / 21177766
larynx3 / 24145124
liver4 / 20774319
lung17 / 33697450
lymph1 / 4427022
lymph node3 / 9161032
mammary gland7 / 15327145
mouth5 / 6705274
muscle2 / 10771518
nerve1 / 1576863
ovary5 / 10205148
pancreas17 / 21481279
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta12 / 28082542
prostate11 / 18934558
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach0 / 966190 
testis12 / 33044236
thymus1 / 8113112
thyroid6 / 47473126
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P377806
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.17 ± 0.43
Basal Forebrain5.67 ± 0.13
Basal Part of Pons5.03 ± 0.55
Cerebellar Cortex5.47 ± 0.44
Cerebellar Nuclei5.31 ± 0.38
Claustrum5.55 ± 0.65
Epithalamus5.13 ± 0.45
Frontal Lobe4.99 ± 0.45
Globus Pallidus5.57 ± 0.41
Hypothalamus5.22 ± 0.53
Insula5.24 ± 0.31
Limbic Lobe5.18 ± 0.59
Mesencephalon5.43 ± 0.59
Myelencephalon5.17 ± 0.51
Occipital Lobe5.69 ± 0.42
Parietal Lobe5.23 ± 0.5
Pontine Tegmentum5.21 ± 0.61
Striatum4.97 ± 0.43
Subthalamus5.18 ± 0.43
Temporal Lobe5.09 ± 0.51
Thalamus5.4 ± 0.43
White Matter5.76 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tnrc6aCBCerebellum58.43
59.57
Tnrc6aCTXCerebral cortex49.53
37.58
Tnrc6aHIPHippocampal region41.22
38.92
Tnrc6aHPFHippocampal formation45.66
39.85
Tnrc6aHYHypothalamus71.94
61.09
Tnrc6aLSXLateral septal complex36.35
26.73
Tnrc6aMBMidbrain64.4
58.26
Tnrc6aMYMedulla58.37
61.93
Tnrc6aOLFOlfactory bulb54.45
45.28
Tnrc6aPPons51.68
54.67
Tnrc6aPALPallidum55.3
47.95
Tnrc6aRHPRetrohippocampal region55.75
42.44
Tnrc6asAMYStriatum-like amygdalar nuclei67.67
57.87
Tnrc6aSTRStriatum24.69
18.17
Tnrc6aSTRdStriatum dorsal region11.49
8.82
Tnrc6aSTRvStriatum ventral region47.65
32.02
Tnrc6aTHThalamus51.21
42.01
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018