AutismKB 2.0

Annotation Detail for TMEM97


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Basic Information Top
Gene Symbol:TMEM97 ( MAC30 )
Gene Full Name: transmembrane protein 97
Band: 17q11.2
Quick LinksEntrez ID:27346; OMIM: 612912; Uniprot ID:TMM97_HUMAN; ENSEMBL ID: ENSG00000109084; HGNC ID: 28106
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst6 / 6231996
fetus65 / 564012115
neonate3 / 3109796
infant4 / 23620169
juvenile14 / 55556251
adult114 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor10 / 94178106
cervical tumor4 / 34366116
chondrosarcoma3 / 8282336
colorectal tumor7 / 11424661
esophageal tumor2 / 17290115
gastrointestinal tumor2 / 11936916
germ cell tumor55 / 263845208
glioma15 / 106883140
head and neck tumor1 / 1363027
kidney tumor5 / 6895972
leukemia14 / 95842146
liver tumor12 / 96359124
lung tumor9 / 10312787
lymphoma6 / 7175583
non-neoplasia1 / 9725010
normal230 / 336030768
ovarian tumor6 / 7668278
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS23 / 125680183
prostate cancer8 / 10268077
retinoblastoma15 / 46356323
skin tumor8 / 12494964
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder7 / 29757235
blood6 / 12347848
bone5 / 7165569
bone marrow3 / 4880161
brain70 / 110098963
cervix7 / 48171145
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus2 / 2020998
eye26 / 211054123
heart3 / 8962633
intestine14 / 23447259
kidney11 / 21177751
larynx0 / 241450 
liver13 / 20774362
lung16 / 33697447
lymph5 / 44270112
lymph node10 / 91610109
mammary gland13 / 15327184
mouth1 / 6705214
muscle8 / 10771574
nerve1 / 1576863
ovary8 / 10205178
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta22 / 28082578
prostate12 / 18934563
salivary gland0 / 201550 
skin21 / 21057499
spleen1 / 5395218
stomach5 / 9661951
testis72 / 330442217
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212282_at
Cell line Expression level Expression bar
721_B_lymphoblasts733.65
Adipocyte65.4
AdrenalCortex141.6
Adrenalgland78.3
Amygdala7.6
Appendix6.9
AtrioventricularNode4.55
BDCA4+_DentriticCells18.1
Bonemarrow6.4
BronchialEpithelialCells39.95
CD105+_Endothelial85.8
CD14+_Monocytes5.15
CD19+_BCells(neg._sel.)6.25
CD33+_Myeloid8.65
CD34+130.15
CD4+_Tcells7.7
CD56+_NKCells11.2
CD71+_EarlyErythroid19.5
CD8+_Tcells6.55
CardiacMyocytes8.3
Caudatenucleus5.95
Cerebellum5.65
CerebellumPeduncles7.1
CiliaryGanglion4.7
CingulateCortex7.05
Colorectaladenocarcinoma40.45
DorsalRootGanglion5.45
FetalThyroid5.45
Fetalbrain10.65
Fetalliver192.1
Fetallung41.25
GlobusPallidus4.9
Heart8
Hypothalamus14.65
Kidney5.7
Leukemia_chronicMyelogenousK-562327.35
Leukemia_promyelocytic-HL-60123.7
Leukemialymphoblastic(MOLT-4)175.35
Liver85.95
Lung21.6
Lymphnode5.35
Lymphoma_burkitts(Daudi)258.4
Lymphoma_burkitts(Raji)15.55
MedullaOblongata6.45
OccipitalLobe6.6
OlfactoryBulb10.95
Ovary4.5
Pancreas378.2
PancreaticIslet115.95
ParietalLobe10.9
Pituitary7.95
Placenta7.05
Pons6.45
PrefrontalCortex9.75
Prostate8.65
Salivarygland4.85
SkeletalMuscle8.85
Skin4.9
SmoothMuscle7.1
Spinalcord10.1
SubthalamicNucleus5.55
SuperiorCervicalGanglion8.9
TemporalLobe11.45
Testis219.65
TestisGermCell282.1
TestisIntersitial113.35
TestisLeydigCell98.2
TestisSeminiferousTubule123.95
Thalamus6.75
Thymus8.65
Thyroid7.8
Tongue6.55
Tonsil7
Trachea5.7
TrigeminalGanglion6.75
Uterus5.6
UterusCorpus6.45
WholeBlood6.85
Wholebrain6.45
colon30.45
pineal_day9.58
pineal_night9.16
retina16.125
small_intestine77.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P151920
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.3 ± 0.54
Basal Forebrain6.52 ± 0.53
Basal Part of Pons6.87 ± 0.15
Cerebellar Cortex6.85 ± 0.26
Cerebellar Nuclei6.93 ± 0.39
Claustrum6.67 ± 0.66
Epithalamus6.55 ± 0.59
Frontal Lobe6.71 ± 0.44
Globus Pallidus5.43 ± 0.46
Hypothalamus6.64 ± 0.55
Insula6.5 ± 0.39
Limbic Lobe6.63 ± 0.5
Mesencephalon6.49 ± 0.57
Myelencephalon6.61 ± 0.62
Occipital Lobe6.74 ± 0.37
Parietal Lobe6.59 ± 0.49
Pontine Tegmentum6.71 ± 0.56
Striatum6.04 ± 0.45
Subthalamus6.09 ± 0.6
Temporal Lobe6.71 ± 0.4
Thalamus6.75 ± 0.67
White Matter5.66 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem97CBCerebellum46.51
62.73
Tmem97CTXCerebral cortex74.43
64.24
Tmem97HIPHippocampal region37.34
46.16
Tmem97HPFHippocampal formation43.07
47.53
Tmem97HYHypothalamus39.84
36.48
Tmem97LSXLateral septal complex18.62
19.88
Tmem97MBMidbrain34.83
36.74
Tmem97MYMedulla49.92
63.13
Tmem97OLFOlfactory bulb75.74
69.34
Tmem97PPons51.58
61.96
Tmem97PALPallidum36.42
37.7
Tmem97RHPRetrohippocampal region55.24
51.63
Tmem97sAMYStriatum-like amygdalar nuclei52.45
44.08
Tmem97STRStriatum31.12
26.31
Tmem97STRdStriatum dorsal region27.49
23.53
Tmem97STRvStriatum ventral region38.47
28.63
Tmem97THThalamus36.54
33.03
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00495314 12 56 67 DPLLQEPPAWFK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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