AutismKB 2.0

Annotation Detail for STK39


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Basic Information Top
Gene Symbol:STK39 ( DCHT,DKFZp686K05124,PASK,SPAK )
Gene Full Name: serine threonine kinase 39
Band: 2q24.3
Quick LinksEntrez ID:27347; OMIM: 607648; Uniprot ID:STK39_HUMAN; ENSEMBL ID: ENSG00000198648; HGNC ID: 17717
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor7 / 26384526
glioma11 / 106883102
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal127 / 336030737
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer18 / 102680175
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder4 / 29757134
blood1 / 1234788
bone3 / 7165541
bone marrow1 / 4880120
brain31 / 110098928
cervix0 / 481710 
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye10 / 21105447
heart4 / 8962644
intestine10 / 23447242
kidney6 / 21177728
larynx0 / 241450 
liver4 / 20774319
lung14 / 33697441
lymph1 / 4427022
lymph node20 / 91610218
mammary gland2 / 15327113
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta2 / 2808257
prostate25 / 189345132
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach6 / 9661962
testis15 / 33044245
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202786_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.2
Adipocyte29.4
AdrenalCortex12.4
Adrenalgland8.85
Amygdala188.6
Appendix11.75
AtrioventricularNode10.45
BDCA4+_DentriticCells13.65
Bonemarrow10.3
BronchialEpithelialCells30.7
CD105+_Endothelial12.25
CD14+_Monocytes16.45
CD19+_BCells(neg._sel.)13.45
CD33+_Myeloid23
CD34+28.7
CD4+_Tcells29
CD56+_NKCells117.3
CD71+_EarlyErythroid8.8
CD8+_Tcells46.75
CardiacMyocytes13.75
Caudatenucleus55.75
Cerebellum21.45
CerebellumPeduncles33.95
CiliaryGanglion14.3
CingulateCortex123.75
Colorectaladenocarcinoma11.75
DorsalRootGanglion10.75
FetalThyroid9.7
Fetalbrain17.15
Fetalliver8.55
Fetallung12
GlobusPallidus42.1
Heart19.8
Hypothalamus163.5
Kidney8.95
Leukemia_chronicMyelogenousK-5627.95
Leukemia_promyelocytic-HL-6054.05
Leukemialymphoblastic(MOLT-4)48.1
Liver15.2
Lung10.05
Lymphnode10.2
Lymphoma_burkitts(Daudi)47.3
Lymphoma_burkitts(Raji)42.3
MedullaOblongata91.5
OccipitalLobe93.45
OlfactoryBulb14.75
Ovary7.1
Pancreas30.3
PancreaticIslet24.55
ParietalLobe72.95
Pituitary66.9
Placenta7.8
Pons26.3
PrefrontalCortex127.2
Prostate55.6
Salivarygland73.3
SkeletalMuscle12.95
Skin9.75
SmoothMuscle20.95
Spinalcord192.4
SubthalamicNucleus55.55
SuperiorCervicalGanglion14.6
TemporalLobe31.4
Testis24.35
TestisGermCell79.6
TestisIntersitial65.75
TestisLeydigCell26.25
TestisSeminiferousTubule34.65
Thalamus178.1
Thymus16.6
Thyroid12.25
Tongue18.95
Tonsil14.25
Trachea111.25
TrigeminalGanglion10.6
Uterus9.95
UterusCorpus9.95
WholeBlood19.9
Wholebrain109.65
colon153.1
pineal_day12.04
pineal_night13.88
retina56.225
small_intestine72
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P19544
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.21 ± 0.63
Basal Forebrain7.54 ± 0.21
Basal Part of Pons8.47 ± 0.23
Cerebellar Cortex7.78 ± 0.2
Cerebellar Nuclei8.61 ± 0.14
Claustrum7.64 ± 0.93
Epithalamus7.28 ± 0.75
Frontal Lobe8.09 ± 0.39
Globus Pallidus8.25 ± 0.25
Hypothalamus7.82 ± 0.36
Insula7.76 ± 0.43
Limbic Lobe7.58 ± 0.55
Mesencephalon7.73 ± 0.56
Myelencephalon7.76 ± 0.54
Occipital Lobe7.18 ± 0.63
Parietal Lobe7.83 ± 0.41
Pontine Tegmentum7.8 ± 0.31
Striatum7.25 ± 0.46
Subthalamus8.33 ± 0.75
Temporal Lobe7.76 ± 0.32
Thalamus7.89 ± 0.4
White Matter9.5 ± 0.13
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001524 25 61 85 DAYELQEVIGSGATAVVQAALCKPR Peptide Atlas
STK39_HUMAN_62 25 62 86 DAYELQEVIGSGATAVVQAALCKPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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