AutismKB 2.0

Annotation Detail for APOBEC3C


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Basic Information Top
Gene Symbol:APOBEC3C ( APOBEC1L,ARDC2,ARDC4,ARP5,MGC19485,PBI,bK150C2.3 )
Gene Full Name: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Band: 22q13.1
Quick LinksEntrez ID:27350; OMIM: 607750; Uniprot ID:ABC3C_HUMAN; ENSEMBL ID: ENSG00000179750,ENSG00000244509; HGNC ID: 17353
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus8 / 56401214
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult81 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor7 / 11424661
esophageal tumor2 / 17290115
gastrointestinal tumor8 / 11936967
germ cell tumor3 / 26384511
glioma8 / 10688374
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor8 / 9635983
lung tumor4 / 10312738
lymphoma10 / 71755139
non-neoplasia3 / 9725030
normal106 / 336030731
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland7 / 33197210
ascites8 / 40015199
bladder1 / 2975733
blood10 / 12347880
bone6 / 7165583
bone marrow8 / 48801163
brain14 / 110098912
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus2 / 2020998
eye5 / 21105423
heart2 / 8962622
intestine8 / 23447234
kidney3 / 21177714
larynx5 / 24145207
liver8 / 20774338
lung14 / 33697441
lymph9 / 44270203
lymph node6 / 9161065
mammary gland5 / 15327132
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta6 / 28082521
prostate4 / 18934521
salivary gland2 / 2015599
skin13 / 21057461
spleen6 / 53952111
stomach0 / 966190 
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil3 / 16999176
trachea3 / 5241357
umbilical cord0 / 136800 
uterus18 / 23287877
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209584_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts365.2
Adipocyte45.8
AdrenalCortex66.35
Adrenalgland46.1
Amygdala48.55
Appendix77.8
AtrioventricularNode57.4
BDCA4+_DentriticCells160.9
Bonemarrow53.35
BronchialEpithelialCells64.3
CD105+_Endothelial193.95
CD14+_Monocytes130.3
CD19+_BCells(neg._sel.)329.3
CD33+_Myeloid72.55
CD34+208
CD4+_Tcells106.45
CD56+_NKCells497.25
CD71+_EarlyErythroid134.55
CD8+_Tcells110.15
CardiacMyocytes68.25
Caudatenucleus44.95
Cerebellum43.05
CerebellumPeduncles85
CiliaryGanglion44.4
CingulateCortex62.1
Colorectaladenocarcinoma123.35
DorsalRootGanglion46.1
FetalThyroid54.6
Fetalbrain48.7
Fetalliver44.85
Fetallung39.15
GlobusPallidus53.4
Heart71.25
Hypothalamus54.65
Kidney44.1
Leukemia_chronicMyelogenousK-56247.8
Leukemia_promyelocytic-HL-6043.85
Leukemialymphoblastic(MOLT-4)40.95
Liver67.05
Lung63.65
Lymphnode56.95
Lymphoma_burkitts(Daudi)80.3
Lymphoma_burkitts(Raji)75.95
MedullaOblongata49.8
OccipitalLobe47.75
OlfactoryBulb44.4
Ovary37
Pancreas44
PancreaticIslet56.55
ParietalLobe61.75
Pituitary63.25
Placenta49.45
Pons51.55
PrefrontalCortex63.5
Prostate138.35
Salivarygland39.7
SkeletalMuscle64.6
Skin48.05
SmoothMuscle88.5
Spinalcord50.65
SubthalamicNucleus69
SuperiorCervicalGanglion69.55
TemporalLobe47.95
Testis48.3
TestisGermCell134.65
TestisIntersitial57.05
TestisLeydigCell58.35
TestisSeminiferousTubule59.8
Thalamus54.05
Thymus71.3
Thyroid65.5
Tongue56.2
Tonsil108.3
Trachea40.85
TrigeminalGanglion58.35
Uterus58.2
UterusCorpus49.9
WholeBlood70.6
Wholebrain37.35
colon86.15
pineal_day57.58
pineal_night59.66
retina68.675
small_intestine83.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P120931
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.23 ± 1.09
Basal Forebrain1.67 ± 0.18
Basal Part of Pons1.69 ± 0.83
Cerebellar Cortex1.55 ± 0.57
Cerebellar Nuclei2.03 ± 0.71
Claustrum2.55 ± 0.79
Epithalamus2.07 ± 0.47
Frontal Lobe1.64 ± 0.66
Globus Pallidus2.59 ± 0.52
Hypothalamus1.82 ± 0.72
Insula1.78 ± 0.63
Limbic Lobe1.69 ± 0.63
Mesencephalon1.92 ± 0.68
Myelencephalon1.81 ± 0.65
Occipital Lobe1.83 ± 0.61
Parietal Lobe1.8 ± 0.78
Pontine Tegmentum1.85 ± 0.72
Striatum2.16 ± 0.71
Subthalamus1.88 ± 0.63
Temporal Lobe1.72 ± 0.7
Thalamus1.83 ± 0.73
White Matter2.32 ± 0.65
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009455 16 70 85 CFLSWFCDDILSPNTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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