AutismKB 2.0

Annotation Detail for GLO1


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Basic Information Top
Gene Symbol:GLO1 ( GLOD1,GLYI )
Gene Full Name: glyoxalase I
Band: 6p21.2
Quick LinksEntrez ID:2739; OMIM: 138750; Uniprot ID:LGUL_HUMAN; ENSEMBL ID: ENSG00000124767; HGNC ID: 4323
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst14 / 62319224
fetus76 / 564012134
neonate14 / 31097450
infant31 / 236201312
juvenile58 / 555561043
adult384 / 1939121198
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma6 / 17475343
breast (mammary gland) tumor32 / 94178339
cervical tumor17 / 34366494
chondrosarcoma17 / 82823205
colorectal tumor27 / 114246236
esophageal tumor25 / 172901445
gastrointestinal tumor32 / 119369268
germ cell tumor91 / 263845344
glioma28 / 106883261
head and neck tumor4 / 13630229
kidney tumor14 / 68959203
leukemia25 / 95842260
liver tumor45 / 96359467
lung tumor9 / 10312787
lymphoma17 / 71755236
non-neoplasia23 / 97250236
normal771 / 3360307229
ovarian tumor20 / 76682260
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS98 / 125680779
prostate cancer26 / 102680253
retinoblastoma21 / 46356453
skin tumor20 / 124949160
soft tissue/muscle tissue tumor38 / 125191303
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland6 / 33197180
ascites14 / 40015349
bladder9 / 29757302
blood32 / 123478259
bone20 / 71655279
bone marrow13 / 48801266
brain335 / 1100989304
cervix20 / 48171415
connective tissue24 / 149255160
ear3 / 16212185
embryonic tissue69 / 215722319
esophagus26 / 202091286
eye54 / 211054255
heart29 / 89626323
intestine54 / 234472230
kidney52 / 211777245
larynx2 / 2414582
liver52 / 207743250
lung54 / 336974160
lymph6 / 44270135
lymph node15 / 91610163
mammary gland55 / 153271358
mouth2 / 6705229
muscle10 / 10771592
nerve6 / 15768380
ovary25 / 102051244
pancreas21 / 21481297
parathyroid9 / 20539438
pharynx5 / 41328120
pituitary gland2 / 16585120
placenta63 / 280825224
prostate58 / 189345306
salivary gland5 / 20155248
skin64 / 210574303
spleen12 / 53952222
stomach19 / 96619196
testis55 / 330442166
thymus25 / 81131308
thyroid2 / 4747342
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord8 / 13680584
uterus69 / 232878296
vascular56 / 517801081
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200681_at
Cell line Expression level Expression bar
721_B_lymphoblasts1388.3
Adipocyte346.15
AdrenalCortex108.45
Adrenalgland165.8
Amygdala543.45
Appendix76.85
AtrioventricularNode73.85
BDCA4+_DentriticCells679.9
Bonemarrow77.2
BronchialEpithelialCells967.45
CD105+_Endothelial464.25
CD14+_Monocytes177.8
CD19+_BCells(neg._sel.)650.9
CD33+_Myeloid157.9
CD34+470.3
CD4+_Tcells203.6
CD56+_NKCells328.7
CD71+_EarlyErythroid378.15
CD8+_Tcells180.5
CardiacMyocytes374.4
Caudatenucleus300.35
Cerebellum63.35
CerebellumPeduncles171.85
CiliaryGanglion73.8
CingulateCortex265.15
Colorectaladenocarcinoma251.85
DorsalRootGanglion107.8
FetalThyroid187.15
Fetalbrain284.05
Fetalliver458.9
Fetallung335.1
GlobusPallidus156.35
Heart21
Hypothalamus572.6
Kidney102.2
Leukemia_chronicMyelogenousK-5621197.05
Leukemia_promyelocytic-HL-601454.9
Leukemialymphoblastic(MOLT-4)794.6
Liver106.4
Lung230.1
Lymphnode187.4
Lymphoma_burkitts(Daudi)884.3
Lymphoma_burkitts(Raji)1575.35
MedullaOblongata282.1
OccipitalLobe404.45
OlfactoryBulb264.45
Ovary193.2
Pancreas131.85
PancreaticIslet225.1
ParietalLobe368.7
Pituitary190.05
Placenta156.65
Pons222.4
PrefrontalCortex564.55
Prostate976.3
Salivarygland185.85
SkeletalMuscle113.6
Skin96.95
SmoothMuscle593.35
Spinalcord487.3
SubthalamicNucleus228.7
SuperiorCervicalGanglion90.65
TemporalLobe267.15
Testis55.95
TestisGermCell189.85
TestisIntersitial60.5
TestisLeydigCell85.1
TestisSeminiferousTubule77.8
Thalamus346.5
Thymus114.6
Thyroid387.5
Tongue176.55
Tonsil123.6
Trachea132
TrigeminalGanglion65.4
Uterus204.05
UterusCorpus107.4
WholeBlood104.2
Wholebrain363.6
colon273.05
pineal_day936.62
pineal_night824.86
retina493.275
small_intestine371.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P214411
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.89 ± 0.33
Basal Forebrain5.86 ± 0.28
Basal Part of Pons5.98 ± 0.25
Cerebellar Cortex5.47 ± 0.23
Cerebellar Nuclei6.06 ± 0.39
Claustrum6.12 ± 0.42
Epithalamus5.93 ± 0.28
Frontal Lobe5.98 ± 0.31
Globus Pallidus5.91 ± 0.37
Hypothalamus5.89 ± 0.37
Insula5.96 ± 0.21
Limbic Lobe5.82 ± 0.45
Mesencephalon5.83 ± 0.37
Myelencephalon5.81 ± 0.39
Occipital Lobe5.49 ± 0.43
Parietal Lobe5.86 ± 0.3
Pontine Tegmentum5.89 ± 0.35
Striatum5.7 ± 0.41
Subthalamus6.23 ± 0.17
Temporal Lobe5.93 ± 0.31
Thalamus5.79 ± 0.31
White Matter5.65 ± 0.68
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Glo1CBCerebellum18.76
37.19
Glo1CTXCerebral cortex14.58
11.93
Glo1HIPHippocampal region50.64
86.6
Glo1HPFHippocampal formation41.01
61.22
Glo1HYHypothalamus19.76
18.57
Glo1LSXLateral septal complex13.74
11.71
Glo1MBMidbrain12.84
15.26
Glo1MYMedulla15.34
25.07
Glo1OLFOlfactory bulb18.01
15.54
Glo1PPons18.74
25.9
Glo1PALPallidum12.78
14.48
Glo1RHPRetrohippocampal region22.83
21.21
Glo1sAMYStriatum-like amygdalar nuclei12.45
10.41
Glo1STRStriatum7.63
7.19
Glo1STRdStriatum dorsal region4.09
4.13
Glo1STRvStriatum ventral region12.49
11.58
Glo1THThalamus31.78
32.73
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LGUL_HUMAN_0 0 0 0 DFLLQQTMLR PRIDE
LGUL_HUMAN_0 0 0 0 GFGHIGIAVPDVYSACK PRIDE
LGUL_HUMAN_123 17 123 139 GFGHIGIAVPDVYSACK PRIDE
LGUL_HUMAN_123 18 123 140 GFGHIGIAVPDVYSACKR PRIDE
LGUL_HUMAN_140 8 140 147 RFEELGVK PRIDE
LGUL_HUMAN_159 20 159 178 GLAFIQDPDGYWIEILNPNK PRIDE
LGUL_HUMAN_28 10 28 37 DFLLQQTMLR PRIDE
LGUL_HUMAN_44 7 44 50 SLDFYTR PRIDE
LGUL_HUMAN_51 9 51 59 VLGMTLIQK PRIDE
LGUL_HUMAN_60 7 60 66 CDFPIMK PRIDE
LGUL_HUMAN_67 16 67 82 FSLYFLAYEDKNDIPK PRIDE
LGUL_HUMAN_88 7 88 94 IAWALSR PRIDE
PAp00000888 7 61 67 CDFPIMK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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