AutismKB 2.0

Annotation Detail for POLM


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Basic Information Top
Gene Symbol:POLM ( FLJ35482,Pol Mu,Tdt-N )
Gene Full Name: polymerase (DNA directed), mu
Band: 7p13
Quick LinksEntrez ID:27434; OMIM: 606344; Uniprot ID:DPOLM_HUMAN; ENSEMBL ID: ENSG00000122678; HGNC ID: 9185
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult73 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor2 / 17290115
gastrointestinal tumor13 / 119369108
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia12 / 95842125
liver tumor12 / 96359124
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia1 / 9725010
normal136 / 336030740
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites10 / 40015249
bladder0 / 297570 
blood13 / 123478105
bone0 / 716550 
bone marrow7 / 48801143
brain54 / 110098949
cervix3 / 4817162
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus3 / 20209148
eye1 / 2110544
heart1 / 8962611
intestine13 / 23447255
kidney15 / 21177770
larynx0 / 241450 
liver13 / 20774362
lung9 / 33697426
lymph1 / 4427022
lymph node10 / 91610109
mammary gland7 / 15327145
mouth5 / 6705274
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta10 / 28082535
prostate5 / 18934526
salivary gland0 / 201550 
skin4 / 21057418
spleen15 / 53952278
stomach2 / 9661920
testis5 / 33044215
thymus33 / 81131406
thyroid2 / 4747342
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222238_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.6
Adipocyte4.8
AdrenalCortex6.2
Adrenalgland5.6
Amygdala5.05
Appendix4.95
AtrioventricularNode3.9
BDCA4+_DentriticCells5.6
Bonemarrow5.05
BronchialEpithelialCells6.25
CD105+_Endothelial4.7
CD14+_Monocytes5.15
CD19+_BCells(neg._sel.)17.05
CD33+_Myeloid6.25
CD34+6.3
CD4+_Tcells8.05
CD56+_NKCells6.15
CD71+_EarlyErythroid4.55
CD8+_Tcells7.45
CardiacMyocytes6.1
Caudatenucleus4.45
Cerebellum4
CerebellumPeduncles5.6
CiliaryGanglion3.6
CingulateCortex7.7
Colorectaladenocarcinoma9.65
DorsalRootGanglion3.85
FetalThyroid5.2
Fetalbrain4.75
Fetalliver4.25
Fetallung4.25
GlobusPallidus3.7
Heart6.3
Hypothalamus5.25
Kidney4.95
Leukemia_chronicMyelogenousK-5624.65
Leukemia_promyelocytic-HL-605.35
Leukemialymphoblastic(MOLT-4)7.45
Liver6.7
Lung5.4
Lymphnode5.9
Lymphoma_burkitts(Daudi)9.75
Lymphoma_burkitts(Raji)11
MedullaOblongata4.6
OccipitalLobe6.1
OlfactoryBulb4.25
Ovary3.25
Pancreas4
PancreaticIslet5.25
ParietalLobe5.25
Pituitary5.75
Placenta5
Pons4.7
PrefrontalCortex6
Prostate6.5
Salivarygland3.9
SkeletalMuscle6.15
Skin3.95
SmoothMuscle5.65
Spinalcord5.3
SubthalamicNucleus4.45
SuperiorCervicalGanglion5.65
TemporalLobe6
Testis4.15
TestisGermCell3.95
TestisIntersitial4.1
TestisLeydigCell4.8
TestisSeminiferousTubule4.25
Thalamus7.55
Thymus6.45
Thyroid8.7
Tongue5.25
Tonsil5.2
Trachea4.4
TrigeminalGanglion5.05
Uterus3.95
UterusCorpus4.4
WholeBlood5.9
Wholebrain4
colon4.8
pineal_day6.18
pineal_night5.9
retina5.825
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16535_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.55 ± 0.89
Basal Forebrain4.11 ± 0.21
Basal Part of Pons4.14 ± 0.44
Cerebellar Cortex4.07 ± 0.51
Cerebellar Nuclei3.98 ± 0.48
Claustrum4.75 ± 0.95
Epithalamus3.68 ± 0.45
Frontal Lobe3.97 ± 0.55
Globus Pallidus4.39 ± 0.59
Hypothalamus3.66 ± 0.49
Insula3.89 ± 0.49
Limbic Lobe4.15 ± 0.61
Mesencephalon4.08 ± 0.71
Myelencephalon4.16 ± 0.6
Occipital Lobe4.15 ± 0.72
Parietal Lobe4.11 ± 0.57
Pontine Tegmentum4.11 ± 0.58
Striatum4.19 ± 0.53
Subthalamus3.61 ± 0.38
Temporal Lobe4.02 ± 0.68
Thalamus4.16 ± 0.56
White Matter5.04 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PolmCBCerebellum12.74
15.94
PolmCTXCerebral cortex12.43
8.58
PolmHIPHippocampal region10.57
10.42
PolmHPFHippocampal formation11.94
10.52
PolmHYHypothalamus6.4
4.71
PolmLSXLateral septal complex2.81
1.72
PolmMBMidbrain16.17
15.27
PolmMYMedulla19.16
19.91
PolmOLFOlfactory bulb12.61
9.03
PolmPPons15.07
16.9
PolmPALPallidum5.32
4.48
PolmRHPRetrohippocampal region14.58
11.02
PolmsAMYStriatum-like amygdalar nuclei4.05
2.84
PolmSTRStriatum6.04
4.15
PolmSTRdStriatum dorsal region5.73
3.92
PolmSTRvStriatum ventral region10.12
6.82
PolmTHThalamus7.38
5.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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