AutismKB 2.0

Annotation Detail for GLUD2


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Basic Information Top
Gene Symbol:GLUD2 ( GDH2,GLUDP1 )
Gene Full Name: glutamate dehydrogenase 2
Band: Xq24
Quick LinksEntrez ID:2747; OMIM: 300144; Uniprot ID:DHE4_HUMAN; ENSEMBL ID: ENSG00000182890; HGNC ID: 4336
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus4 / 5640127
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal37 / 336030711
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor8 / 12494964
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood10 / 12347880
bone0 / 716550 
bone marrow0 / 488010 
brain20 / 110098918
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver3 / 20774314
lung3 / 3369748
lymph2 / 4427045
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach3 / 9661931
testis9 / 33044227
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210447_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.75
Adipocyte4.8
AdrenalCortex5.4
Adrenalgland4.25
Amygdala4.95
Appendix5.25
AtrioventricularNode4
BDCA4+_DentriticCells5
Bonemarrow5.1
BronchialEpithelialCells4.7
CD105+_Endothelial4.85
CD14+_Monocytes5.15
CD19+_BCells(neg._sel.)5
CD33+_Myeloid6.05
CD34+5.95
CD4+_Tcells5.05
CD56+_NKCells5.6
CD71+_EarlyErythroid4.6
CD8+_Tcells4.5
CardiacMyocytes6.75
Caudatenucleus4.4
Cerebellum3.95
CerebellumPeduncles5.6
CiliaryGanglion3.65
CingulateCortex5
Colorectaladenocarcinoma4.9
DorsalRootGanglion4
FetalThyroid4.8
Fetalbrain4.7
Fetalliver4.3
Fetallung3.9
GlobusPallidus3.65
Heart6.65
Hypothalamus5.15
Kidney4.1
Leukemia_chronicMyelogenousK-5624.4
Leukemia_promyelocytic-HL-604.3
Leukemialymphoblastic(MOLT-4)3.85
Liver6.65
Lung5.25
Lymphnode4.05
Lymphoma_burkitts(Daudi)6.3
Lymphoma_burkitts(Raji)7.1
MedullaOblongata4.4
OccipitalLobe4.3
OlfactoryBulb3.85
Ovary3.4
Pancreas3.95
PancreaticIslet5.25
ParietalLobe5.3
Pituitary5.65
Placenta4.85
Pons4.65
PrefrontalCortex5.85
Prostate5.55
Salivarygland3.95
SkeletalMuscle5.95
Skin3.95
SmoothMuscle5.45
Spinalcord5.15
SubthalamicNucleus4.5
SuperiorCervicalGanglion5.95
TemporalLobe4.5
Testis4.2
TestisGermCell5.1
TestisIntersitial4.15
TestisLeydigCell4.95
TestisSeminiferousTubule4.2
Thalamus5
Thymus3.75
Thyroid5.95
Tongue5.05
Tonsil4.75
Trachea4.05
TrigeminalGanglion5.55
Uterus3.9
UterusCorpus4.5
WholeBlood5.3
Wholebrain3.9
colon4.9
pineal_day6
pineal_night5.92
retina5.85
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P45361
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.25 ± 0.23
Basal Forebrain9.19 ± 0.12
Basal Part of Pons8.45 ± 0.34
Cerebellar Cortex8.34 ± 0.24
Cerebellar Nuclei8.27 ± 0.48
Claustrum8.46 ± 0.57
Epithalamus8.97 ± 0.37
Frontal Lobe8.8 ± 0.39
Globus Pallidus9.58 ± 0.16
Hypothalamus9.15 ± 0.14
Insula9 ± 0.44
Limbic Lobe8.71 ± 0.49
Mesencephalon9.07 ± 0.43
Myelencephalon8.93 ± 0.44
Occipital Lobe8.64 ± 0.3
Parietal Lobe8.78 ± 0.47
Pontine Tegmentum8.94 ± 0.45
Striatum9.5 ± 0.29
Subthalamus8.53 ± 0.38
Temporal Lobe8.96 ± 0.36
Thalamus9.21 ± 0.39
White Matter8.76 ± 0.04
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DHE4_HUMAN_107 16 107 122 IIKPCNHVLSLSFPIR PRIDE
DHE4_HUMAN_151 11 151 161 YSTDVSVDEVK PRIDE
DHE4_HUMAN_171 12 171 182 CAVVDVPFGGAK PRIDE
DHE4_HUMAN_527 8 527 534 YNLGLDLR PRIDE
DHE4_HUMAN_68 8 68 75 MVEGFFDR PRIDE
PAp00000482 23 364 386 AKPYEGSILEVDCDILIPAATEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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