Annotation Detail for GMDS
Basic Information Top
| Gene Symbol: | GMDS ( GMD,SDR3E1 ) |
|---|---|
| Gene Full Name: | GDP-mannose 4,6-dehydratase |
| Band: | 6p25.3 |
| Quick Links | Entrez ID:2762; OMIM: 602884; Uniprot ID:GMDS_HUMAN; ENSEMBL ID: ENSG00000112699; HGNC ID: 4369 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.660919
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 7 / 564012 | 12 | |
| neonate | 0 / 31097 | 0 | |
| infant | 2 / 23620 | 84 |  |
| juvenile | 2 / 55556 | 35 | |
| adult | 108 / 1939121 | 55 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 4 / 1939121 | 2 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 55 / 114246 | 481 |  |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 9 / 119369 | 75 | |
| germ cell tumor | 7 / 263845 | 26 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 12 / 136302 | 88 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 8 / 96359 | 83 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 79 / 3360307 | 23 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 7 / 125680 | 55 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 6 / 90257 | 66 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 0 / 3360307 | 0 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 0 / 29757 | 0 | |
| blood | 5 / 123478 | 40 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 14 / 1100989 | 12 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 4 / 211054 | 18 | |
| heart | 0 / 89626 | 0 | |
| intestine | 80 / 234472 | 341 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 3 / 24145 | 124 | |
| liver | 10 / 207743 | 48 | |
| lung | 13 / 336974 | 38 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 6 / 91610 | 65 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 4 / 102051 | 39 | |
| pancreas | 11 / 214812 | 51 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 6 / 280825 | 21 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 10 / 20155 | 496 | |
| skin | 4 / 210574 | 18 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 8 / 96619 | 82 | |
| testis | 14 / 330442 | 42 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 1 / 51780 | 19 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 214106_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 15.95 | |
| Adipocyte | 8.4 | |
| AdrenalCortex | 9.55 | |
| Adrenalgland | 7.4 | |
| Amygdala | 7.75 | |
| Appendix | 10.65 | |
| AtrioventricularNode | 10.8 | |
| BDCA4+_DentriticCells | 12.6 | |
| Bonemarrow | 10.5 | |
| BronchialEpithelialCells | 11.5 | |
| CD105+_Endothelial | 12.3 | |
| CD14+_Monocytes | 25.5 | |
| CD19+_BCells(neg._sel.) | 12.8 | |
| CD33+_Myeloid | 15.8 | |
| CD34+ | 24.9 | |
| CD4+_Tcells | 9.3 | |
| CD56+_NKCells | 17.15 | |
| CD71+_EarlyErythroid | 8.15 | |
| CD8+_Tcells | 7.8 | |
| CardiacMyocytes | 12.2 | |
| Caudatenucleus | 7.45 | |
| Cerebellum | 7 | |
| CerebellumPeduncles | 10.15 | |
| CiliaryGanglion | 7.2 | |
| CingulateCortex | 8.85 | |
| Colorectaladenocarcinoma | 11.05 | |
| DorsalRootGanglion | 8 | |
| FetalThyroid | 8.55 | |
| Fetalbrain | 8.5 | |
| Fetalliver | 7.8 | |
| Fetallung | 6.6 | |
| GlobusPallidus | 6.65 | |
| Heart | 9.65 | |
| Hypothalamus | 8.65 | |
| Kidney | 8.6 | |
| Leukemia_chronicMyelogenousK-562 | 7.85 | |
| Leukemia_promyelocytic-HL-60 | 7.7 | |
| Leukemialymphoblastic(MOLT-4) | 16 | |
| Liver | 13.05 | |
| Lung | 10.7 | |
| Lymphnode | 7.85 | |
| Lymphoma_burkitts(Daudi) | 11.15 | |
| Lymphoma_burkitts(Raji) | 13.85 | |
| MedullaOblongata | 7.65 | |
| OccipitalLobe | 7.4 | |
| OlfactoryBulb | 9 | |
| Ovary | 6 | |
| Pancreas | 16.15 | |
| PancreaticIslet | 9.8 | |
| ParietalLobe | 9.45 | |
| Pituitary | 11.7 | |
| Placenta | 8.1 | |
| Pons | 8.6 | |
| PrefrontalCortex | 9.3 | |
| Prostate | 21 | |
| Salivarygland | 45.7 | |
| SkeletalMuscle | 23.6 | |
| Skin | 10.2 | |
| SmoothMuscle | 9.45 | |
| Spinalcord | 8.7 | |
| SubthalamicNucleus | 7.9 | |
| SuperiorCervicalGanglion | 10.85 | |
| TemporalLobe | 8 | |
| Testis | 7.25 | |
| TestisGermCell | 7.15 | |
| TestisIntersitial | 7.25 | |
| TestisLeydigCell | 8.8 | |
| TestisSeminiferousTubule | 7.2 | |
| Thalamus | 8.75 | |
| Thymus | 8.1 | |
| Thyroid | 10 | |
| Tongue | 9.4 | |
| Tonsil | 9.7 | |
| Trachea | 19.25 | |
| TrigeminalGanglion | 11.4 | |
| Uterus | 6.5 | |
| UterusCorpus | 9.55 | |
| WholeBlood | 8.8 | |
| Wholebrain | 6.65 | |
| colon | 70.8 | |
| pineal_day | 10.28 | |
| pineal_night | 10.48 | |
| retina | 23.575 | |
| small_intestine | 36.35 | |
- Probe name: CUST_8674_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.87 ± 0.42 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.7 ± 0.45 | |
| Basal Part of Pons | 4.37 ± 0.46 | |
| Cerebellar Cortex | 4.52 ± 0.39 | |
| Cerebellar Nuclei | 4.22 ± 0.56 | |
| Claustrum | 4.52 ± 0.83 | |
| Epithalamus | 4 ± 0.41 | |
| Frontal Lobe | 4.29 ± 0.56 | |
| Globus Pallidus | 4.27 ± 0.39 | |
| Hypothalamus | 4.42 ± 0.38 | |
| Insula | 4.53 ± 0.28 | |
| Limbic Lobe | 4.65 ± 0.5 | |
| Mesencephalon | 4.51 ± 0.6 | |
| Myelencephalon | 4.42 ± 0.56 | |
| Occipital Lobe | 4.71 ± 0.64 | |
| Parietal Lobe | 4.44 ± 0.49 | |
| Pontine Tegmentum | 4.61 ± 0.6 | |
| Striatum | 4.97 ± 0.47 | |
| Subthalamus | 3.91 ± 0.69 | |
| Temporal Lobe | 4.47 ± 0.56 | |
| Thalamus | 4.4 ± 0.48 | |
| White Matter | 4.06 ± 0.61 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Gmds | CB | Cerebellum | 0.45 | |
| 0.81 | | |||
| Gmds | CTX | Cerebral cortex | 0.16 | |
| 0.27 | | |||
| Gmds | HIP | Hippocampal region | 0.36 | |
| 0.44 | | |||
| Gmds | HPF | Hippocampal formation | 0.67 | |
| 0.81 | | |||
| Gmds | HY | Hypothalamus | 0.63 | |
| 1.81 | | |||
| Gmds | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Gmds | MB | Midbrain | 0.9 | |
| 1.44 | | |||
| Gmds | MY | Medulla | 1.44 | |
| 2.11 | | |||
| Gmds | OLF | Olfactory bulb | 1.6 | |
| 3.2 | | |||
| Gmds | P | Pons | 2.13 | |
| 5.24 | | |||
| Gmds | PAL | Pallidum | 0.22 | |
| 0.34 | | |||
| Gmds | RHP | Retrohippocampal region | 1.48 | |
| 1.68 | | |||
| Gmds | sAMY | Striatum-like amygdalar nuclei | 4.28 | |
| 4.27 | | |||
| Gmds | STR | Striatum | 0.37 | |
| 0.43 | | |||
| Gmds | STRd | Striatum dorsal region | 0.04 | |
| 0.06 | | |||
| Gmds | STRv | Striatum ventral region | 0.48 | |
| 0.62 | | |||
| Gmds | TH | Thalamus | 0.07 | |
| 0.13 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| GMDS_HUMAN_357 | 11 | 357 | 367 | EMVHADVELMR | PRIDE |
| PAp00004988 | 14 | 82 | 95 | LHYGDLTDSTCLVK | Peptide Atlas |