AutismKB 2.0

Annotation Detail for GNA15


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Basic Information Top
Gene Symbol:GNA15 ( GNA16 )
Gene Full Name: guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
Band: 19p13.3
Quick LinksEntrez ID:2769; OMIM: 139314; Uniprot ID:GNA15_HUMAN; ENSEMBL ID: ENSG00000060558; HGNC ID: 4383
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus12 / 56401221
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor3 / 17290173
gastrointestinal tumor1 / 1193698
germ cell tumor12 / 26384545
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia7 / 9584273
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal57 / 336030716
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood8 / 12347864
bone0 / 716550 
bone marrow1 / 4880120
brain6 / 11009895
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus3 / 20209148
eye3 / 21105414
heart0 / 896260 
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver3 / 20774314
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth5 / 6705274
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate10 / 18934552
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus25 / 81131308
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205349_at
Cell line Expression level Expression bar
721_B_lymphoblasts23.25
Adipocyte9.3
AdrenalCortex9.95
Adrenalgland7.85
Amygdala8.8
Appendix9.35
AtrioventricularNode7
BDCA4+_DentriticCells356.65
Bonemarrow14.8
BronchialEpithelialCells286.7
CD105+_Endothelial34.15
CD14+_Monocytes133.85
CD19+_BCells(neg._sel.)10.05
CD33+_Myeloid157.4
CD34+347.4
CD4+_Tcells10.1
CD56+_NKCells11.25
CD71+_EarlyErythroid9.2
CD8+_Tcells7.85
CardiacMyocytes11.9
Caudatenucleus8.05
Cerebellum7.25
CerebellumPeduncles10.7
CiliaryGanglion6.5
CingulateCortex9.65
Colorectaladenocarcinoma7.9
DorsalRootGanglion8
FetalThyroid9.1
Fetalbrain8.55
Fetalliver8.05
Fetallung14.2
GlobusPallidus6.85
Heart11.95
Hypothalamus10.15
Kidney7.55
Leukemia_chronicMyelogenousK-5628.45
Leukemia_promyelocytic-HL-607.3
Leukemialymphoblastic(MOLT-4)304.15
Liver13.95
Lung57.3
Lymphnode8
Lymphoma_burkitts(Daudi)10.55
Lymphoma_burkitts(Raji)13
MedullaOblongata8.7
OccipitalLobe8.45
OlfactoryBulb8.8
Ovary6.15
Pancreas7.45
PancreaticIslet9.6
ParietalLobe9.8
Pituitary10
Placenta9.25
Pons8.9
PrefrontalCortex11.85
Prostate17.15
Salivarygland7.8
SkeletalMuscle11.2
Skin8
SmoothMuscle8.1
Spinalcord12.3
SubthalamicNucleus8.6
SuperiorCervicalGanglion10.9
TemporalLobe10.7
Testis7.45
TestisGermCell7.15
TestisIntersitial6.9
TestisLeydigCell9.35
TestisSeminiferousTubule9.25
Thalamus9.55
Thymus65.65
Thyroid11.7
Tongue48.6
Tonsil10.35
Trachea7.3
TrigeminalGanglion16.8
Uterus7.05
UterusCorpus11.35
WholeBlood40.7
Wholebrain7.85
colon9.1
pineal_day12.4
pineal_night11
retina10.8
small_intestine9.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8897_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.7 ± 0.71
Basal Forebrain3.01 ± 0.16
Basal Part of Pons3.18 ± 0.53
Cerebellar Cortex3.91 ± 0.31
Cerebellar Nuclei3.55 ± 0.66
Claustrum3.46 ± 0.71
Epithalamus2.78 ± 0.8
Frontal Lobe3.62 ± 0.62
Globus Pallidus2.58 ± 0.52
Hypothalamus3.14 ± 0.69
Insula2.99 ± 0.7
Limbic Lobe3.56 ± 0.58
Mesencephalon3.41 ± 0.76
Myelencephalon3.37 ± 0.7
Occipital Lobe3.05 ± 0.69
Parietal Lobe3.4 ± 0.63
Pontine Tegmentum3.35 ± 0.69
Striatum2.32 ± 0.61
Subthalamus3.71 ± 0.49
Temporal Lobe3.43 ± 0.66
Thalamus3.04 ± 0.66
White Matter2.3 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gna15CBCerebellum0.36
0.5
Gna15CTXCerebral cortex0.43
0.51
Gna15HIPHippocampal region0.17
0.21
Gna15HPFHippocampal formation0.15
0.21
Gna15HYHypothalamus1.62
2.21
Gna15LSXLateral septal complex0
0
Gna15MBMidbrain0.18
0.3
Gna15MYMedulla0.11
0.17
Gna15OLFOlfactory bulb0.59
1.8
Gna15PPons0.12
0.27
Gna15PALPallidum0.07
0.04
Gna15RHPRetrohippocampal region0.1
0.2
Gna15sAMYStriatum-like amygdalar nuclei0.56
0.44
Gna15STRStriatum0.12
0.12
Gna15STRdStriatum dorsal region0.09
0.1
Gna15STRvStriatum ventral region0.04
0.03
Gna15THThalamus0.01
0.01
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004876 15 339 353 LFSHYTCATDTQNIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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