AutismKB 2.0

Annotation Detail for GNG11


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Basic Information Top
Gene Symbol:GNG11 ( GNGT11 )
Gene Full Name: guanine nucleotide binding protein (G protein), gamma 11
Band: 7q21.3
Quick LinksEntrez ID:2791; OMIM: 604390; Uniprot ID:GBG11_HUMAN; ENSEMBL ID: ENSG00000127920; HGNC ID: 4403
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate4 / 31097128
infant0 / 236200 
juvenile0 / 555560 
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal107 / 336030731
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow1 / 4880120
brain24 / 110098921
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye11 / 21105452
heart3 / 8962633
intestine1 / 2344724
kidney8 / 21177737
larynx0 / 241450 
liver6 / 20774328
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle10 / 10771592
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta23 / 28082581
prostate3 / 18934515
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach2 / 9661920
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord4 / 13680292
uterus6 / 23287825
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204115_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.25
Adipocyte45.65
AdrenalCortex15.95
Adrenalgland31
Amygdala11.5
Appendix143.85
AtrioventricularNode11.1
BDCA4+_DentriticCells13.05
Bonemarrow12.7
BronchialEpithelialCells9.35
CD105+_Endothelial14.35
CD14+_Monocytes42.5
CD19+_BCells(neg._sel.)40.4
CD33+_Myeloid12.4
CD34+14.95
CD4+_Tcells8.25
CD56+_NKCells10.85
CD71+_EarlyErythroid6.85
CD8+_Tcells7.05
CardiacMyocytes398.4
Caudatenucleus11
Cerebellum10.1
CerebellumPeduncles12.7
CiliaryGanglion12.95
CingulateCortex11.4
Colorectaladenocarcinoma14
DorsalRootGanglion12.8
FetalThyroid64.25
Fetalbrain7.25
Fetalliver11.9
Fetallung56.05
GlobusPallidus8.95
Heart41.4
Hypothalamus24.3
Kidney19.75
Leukemia_chronicMyelogenousK-5628.8
Leukemia_promyelocytic-HL-607.25
Leukemialymphoblastic(MOLT-4)7.3
Liver18.7
Lung197.25
Lymphnode26.9
Lymphoma_burkitts(Daudi)15.25
Lymphoma_burkitts(Raji)14.85
MedullaOblongata9.55
OccipitalLobe10.7
OlfactoryBulb19.25
Ovary37.95
Pancreas10.3
PancreaticIslet34.75
ParietalLobe11.9
Pituitary17.25
Placenta439.8
Pons12.6
PrefrontalCortex16.6
Prostate34.15
Salivarygland10.25
SkeletalMuscle16.1
Skin15.9
SmoothMuscle690.65
Spinalcord17.85
SubthalamicNucleus11.6
SuperiorCervicalGanglion16.6
TemporalLobe12.85
Testis10
TestisGermCell13
TestisIntersitial13
TestisLeydigCell11.35
TestisSeminiferousTubule10.1
Thalamus15.1
Thymus75.1
Thyroid93.2
Tongue14.1
Tonsil13
Trachea10.65
TrigeminalGanglion14.1
Uterus115.75
UterusCorpus13.4
WholeBlood328.1
Wholebrain10.45
colon63.3
pineal_day87.76
pineal_night138.64
retina428.475
small_intestine100
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5516_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.02 ± 0.47
Basal Forebrain6.27 ± 0.18
Basal Part of Pons6.14 ± 0.35
Cerebellar Cortex6.11 ± 0.21
Cerebellar Nuclei7.15 ± 0.48
Claustrum5.82 ± 0.56
Epithalamus6.49 ± 0.59
Frontal Lobe6.5 ± 0.41
Globus Pallidus7.48 ± 0.2
Hypothalamus6.33 ± 0.6
Insula6.45 ± 0.29
Limbic Lobe6.33 ± 0.51
Mesencephalon6.55 ± 0.49
Myelencephalon6.55 ± 0.49
Occipital Lobe6.58 ± 0.5
Parietal Lobe6.26 ± 0.44
Pontine Tegmentum6.64 ± 0.48
Striatum7.31 ± 0.45
Subthalamus6.95 ± 0.33
Temporal Lobe6.29 ± 0.37
Thalamus6.66 ± 0.41
White Matter6.49 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gng11CBCerebellum26.99
18.28
Gng11CTXCerebral cortex12.45
7.81
Gng11HIPHippocampal region16.05
9.28
Gng11HPFHippocampal formation17.02
12.08
Gng11HYHypothalamus12.66
8.64
Gng11LSXLateral septal complex4.74
2.88
Gng11MBMidbrain19.4
14.3
Gng11MYMedulla39.87
30.02
Gng11OLFOlfactory bulb21.18
13.16
Gng11PPons52.9
39.48
Gng11PALPallidum7.91
6.63
Gng11RHPRetrohippocampal region18.25
14.3
Gng11sAMYStriatum-like amygdalar nuclei11.85
7.1
Gng11STRStriatum6.97
4.4
Gng11STRdStriatum dorsal region6.52
4.29
Gng11STRvStriatum ventral region6.03
3.46
Gng11THThalamus13.29
8.25
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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