AutismKB 2.0

Annotation Detail for GNRH1


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Basic Information Top
Gene Symbol:GNRH1 ( GNRH,GRH,LHRH,LNRH )
Gene Full Name: gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
Band: 8p21.2
Quick LinksEntrez ID:2796; OMIM: 152760; Uniprot ID:GON1_HUMAN; ENSEMBL ID: ENSG00000147437; HGNC ID: 4419
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal28 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207987_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.25
Adipocyte9.25
AdrenalCortex15.7
Adrenalgland9.35
Amygdala9.25
Appendix14.15
AtrioventricularNode12.75
BDCA4+_DentriticCells8.35
Bonemarrow12.25
BronchialEpithelialCells8.95
CD105+_Endothelial9.05
CD14+_Monocytes10.5
CD19+_BCells(neg._sel.)9.5
CD33+_Myeloid11.4
CD34+10.85
CD4+_Tcells8.7
CD56+_NKCells10.55
CD71+_EarlyErythroid9.55
CD8+_Tcells7.9
CardiacMyocytes24.3
Caudatenucleus8.75
Cerebellum8.05
CerebellumPeduncles13.4
CiliaryGanglion11.3
CingulateCortex10.75
Colorectaladenocarcinoma9.55
DorsalRootGanglion10.55
FetalThyroid10.35
Fetalbrain8.85
Fetalliver8.85
Fetallung7.2
GlobusPallidus8.75
Heart21.45
Hypothalamus10.1
Kidney10.1
Leukemia_chronicMyelogenousK-5628.75
Leukemia_promyelocytic-HL-608.65
Leukemialymphoblastic(MOLT-4)7.6
Liver17.85
Lung10.4
Lymphnode7.85
Lymphoma_burkitts(Daudi)13.5
Lymphoma_burkitts(Raji)16.8
MedullaOblongata8.25
OccipitalLobe8.6
OlfactoryBulb7.35
Ovary8.5
Pancreas8.8
PancreaticIslet10.6
ParietalLobe12
Pituitary11.35
Placenta8.7
Pons10.2
PrefrontalCortex10.7
Prostate10.85
Salivarygland8.55
SkeletalMuscle23.5
Skin11.45
SmoothMuscle10.85
Spinalcord10.3
SubthalamicNucleus10.2
SuperiorCervicalGanglion19.6
TemporalLobe9.4
Testis8.25
TestisGermCell7.25
TestisIntersitial8.55
TestisLeydigCell10.9
TestisSeminiferousTubule8.35
Thalamus10.5
Thymus6.8
Thyroid10.65
Tongue13.1
Tonsil9.85
Trachea7.85
TrigeminalGanglion15.45
Uterus7.4
UterusCorpus11.6
WholeBlood10.3
Wholebrain7.3
colon9.4
pineal_day11.36
pineal_night11.14
retina11.1
small_intestine9.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P254594
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.27 ± 0.61
Basal Forebrain4.67 ± 0.41
Basal Part of Pons4.52 ± 0.46
Cerebellar Cortex4.73 ± 0.36
Cerebellar Nuclei4.5 ± 0.4
Claustrum3.76 ± 0.82
Epithalamus4.86 ± 0.6
Frontal Lobe4.11 ± 0.53
Globus Pallidus4.66 ± 0.54
Hypothalamus4.71 ± 1.56
Insula4.07 ± 0.33
Limbic Lobe4.11 ± 0.66
Mesencephalon4.29 ± 0.67
Myelencephalon4.29 ± 0.69
Occipital Lobe4.87 ± 0.59
Parietal Lobe4.31 ± 0.6
Pontine Tegmentum4.38 ± 0.69
Striatum5.42 ± 1.15
Subthalamus3.91 ± 0.51
Temporal Lobe4.12 ± 0.5
Thalamus4.29 ± 0.44
White Matter4.63 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gnrh1CBCerebellum0.58
0.83
Gnrh1CTXCerebral cortex0.35
0.31
Gnrh1HIPHippocampal region0.19
0.37
Gnrh1HPFHippocampal formation0.28
0.42
Gnrh1HYHypothalamus0.31
0.61
Gnrh1LSXLateral septal complex0.21
0.27
Gnrh1MBMidbrain0.35
0.45
Gnrh1MYMedulla0.4
0.45
Gnrh1OLFOlfactory bulb0.45
1.14
Gnrh1PPons0.52
0.56
Gnrh1PALPallidum0.18
0.27
Gnrh1RHPRetrohippocampal region0.4
0.46
Gnrh1sAMYStriatum-like amygdalar nuclei0.09
0.06
Gnrh1STRStriatum0.18
0.13
Gnrh1STRdStriatum dorsal region0.19
0.14
Gnrh1STRvStriatum ventral region0.2
0.1
Gnrh1THThalamus0.15
0.16
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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