AutismKB 2.0

Annotation Detail for GNRHR


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Basic Information Top
Gene Symbol:GNRHR ( GNRHR1,GRHR,LHRHR,LRHR )
Gene Full Name: gonadotropin-releasing hormone receptor
Band: 4q13.2
Quick LinksEntrez ID:2798; OMIM: 138850; Uniprot ID:GNRHR_HUMAN; ENSEMBL ID: ENSG00000109163; HGNC ID: 4421
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal2 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211522_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.05
Adipocyte7.1
AdrenalCortex9.4
Adrenalgland6.5
Amygdala7.6
Appendix10.6
AtrioventricularNode10.05
BDCA4+_DentriticCells6.9
Bonemarrow8.15
BronchialEpithelialCells6.95
CD105+_Endothelial7.2
CD14+_Monocytes7.85
CD19+_BCells(neg._sel.)7.35
CD33+_Myeloid8.6
CD34+8.45
CD4+_Tcells6.95
CD56+_NKCells8.2
CD71+_EarlyErythroid7.1
CD8+_Tcells6.6
CardiacMyocytes12.1
Caudatenucleus6.6
Cerebellum6.15
CerebellumPeduncles8.95
CiliaryGanglion8
CingulateCortex8
Colorectaladenocarcinoma7.2
DorsalRootGanglion6.8
FetalThyroid7.35
Fetalbrain7.35
Fetalliver6.6
Fetallung6.15
GlobusPallidus5.95
Heart11.75
Hypothalamus7.7
Kidney6.7
Leukemia_chronicMyelogenousK-5626.6
Leukemia_promyelocytic-HL-606.45
Leukemialymphoblastic(MOLT-4)5.55
Liver12
Lung8
Lymphnode6.1
Lymphoma_burkitts(Daudi)9.8
Lymphoma_burkitts(Raji)11.5
MedullaOblongata6.6
OccipitalLobe6.6
OlfactoryBulb5.75
Ovary6.4
Pancreas6.3
PancreaticIslet7.9
ParietalLobe8.35
Pituitary25.9
Placenta7.45
Pons7.35
PrefrontalCortex8.55
Prostate8.25
Salivarygland6.55
SkeletalMuscle13.65
Skin7.95
SmoothMuscle8.35
Spinalcord7.75
SubthalamicNucleus7.7
SuperiorCervicalGanglion14.85
TemporalLobe7
Testis6.35
TestisGermCell5.95
TestisIntersitial6.4
TestisLeydigCell7.65
TestisSeminiferousTubule6.45
Thalamus7.9
Thymus5.75
Thyroid8.9
Tongue9.2
Tonsil7.35
Trachea6.15
TrigeminalGanglion10.65
Uterus5.8
UterusCorpus8.45
WholeBlood8.05
Wholebrain5.75
colon7.1
pineal_day8.72
pineal_night8.56
retina8.85
small_intestine6.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P155804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.09 ± 0.99
Basal Forebrain1.64 ± 0.2
Basal Part of Pons1.34 ± 0.34
Cerebellar Cortex1.49 ± 0.76
Cerebellar Nuclei1.93 ± 0.74
Claustrum2.59 ± 0.92
Epithalamus1.36 ± 0.75
Frontal Lobe1.48 ± 0.62
Globus Pallidus2.31 ± 0.38
Hypothalamus1.81 ± 0.75
Insula1.67 ± 0.79
Limbic Lobe1.65 ± 0.65
Mesencephalon1.84 ± 0.71
Myelencephalon1.69 ± 0.75
Occipital Lobe1.74 ± 0.82
Parietal Lobe1.67 ± 0.7
Pontine Tegmentum1.76 ± 0.83
Striatum1.94 ± 0.7
Subthalamus1.8 ± 0.7
Temporal Lobe1.56 ± 0.72
Thalamus1.63 ± 0.59
White Matter2.09 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
GnrhrCBCerebellum0.35
0.78
GnrhrCTXCerebral cortex1.53
2.52
GnrhrHIPHippocampal region0.23
0.36
GnrhrHPFHippocampal formation0.25
0.43
GnrhrHYHypothalamus0.11
0.13
GnrhrLSXLateral septal complex0.06
0
GnrhrMBMidbrain1.82
2.91
GnrhrMYMedulla0.21
0.38
GnrhrOLFOlfactory bulb0.13
0.21
GnrhrPPons0.17
0.26
GnrhrPALPallidum0.14
0.19
GnrhrRHPRetrohippocampal region0.3
0.55
GnrhrsAMYStriatum-like amygdalar nuclei0.9
0.78
GnrhrSTRStriatum0.28
0.42
GnrhrSTRdStriatum dorsal region0.28
0.52
GnrhrSTRvStriatum ventral region0
0
GnrhrTHThalamus0.19
0.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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