AutismKB 2.0

Annotation Detail for GPD2


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Basic Information Top
Gene Symbol:GPD2 ( GDH2,GPDM,mGPDH )
Gene Full Name: glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
Band: 2q24.1
Quick LinksEntrez ID:2820; OMIM: 138430; Uniprot ID:GPDM_HUMAN; ENSEMBL ID: ENSG00000115159; HGNC ID: 4456
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus45 / 56401279
neonate4 / 31097128
infant0 / 236200 
juvenile1 / 5555617
adult74 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor9 / 26384534
glioma3 / 10688328
head and neck tumor15 / 136302110
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal159 / 336030747
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain54 / 110098949
cervix0 / 481710 
connective tissue6 / 14925540
ear4 / 16212246
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine12 / 23447251
kidney7 / 21177733
larynx1 / 2414541
liver8 / 20774338
lung11 / 33697432
lymph0 / 442700 
lymph node2 / 9161021
mammary gland6 / 15327139
mouth11 / 67052164
muscle9 / 10771583
nerve1 / 1576863
ovary6 / 10205158
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta5 / 28082517
prostate6 / 18934531
salivary gland0 / 201550 
skin9 / 21057442
spleen1 / 5395218
stomach7 / 9661972
testis16 / 33044248
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea12 / 52413228
umbilical cord0 / 136800 
uterus13 / 23287855
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210007_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.05
Adipocyte6.3
AdrenalCortex7.65
Adrenalgland5.6
Amygdala6.45
Appendix13.9
AtrioventricularNode6.15
BDCA4+_DentriticCells6.4
Bonemarrow6.7
BronchialEpithelialCells6.4
CD105+_Endothelial6.25
CD14+_Monocytes11.65
CD19+_BCells(neg._sel.)7.6
CD33+_Myeloid9.9
CD34+8
CD4+_Tcells6.75
CD56+_NKCells9.05
CD71+_EarlyErythroid6.1
CD8+_Tcells5.9
CardiacMyocytes10.1
Caudatenucleus5.8
Cerebellum5.25
CerebellumPeduncles7.65
CiliaryGanglion5.1
CingulateCortex6.65
Colorectaladenocarcinoma6.45
DorsalRootGanglion5.2
FetalThyroid6.25
Fetalbrain6.25
Fetalliver5.65
Fetallung4.9
GlobusPallidus5.1
Heart9.8
Hypothalamus6.7
Kidney5.45
Leukemia_chronicMyelogenousK-5625.75
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)5
Liver9.2
Lung6.95
Lymphnode5.3
Lymphoma_burkitts(Daudi)8.4
Lymphoma_burkitts(Raji)9.5
MedullaOblongata5.8
OccipitalLobe5.7
OlfactoryBulb5.05
Ovary4.6
Pancreas5.6
PancreaticIslet6.9
ParietalLobe7
Pituitary7.45
Placenta6.4
Pons6.25
PrefrontalCortex7.8
Prostate7.3
Salivarygland5.35
SkeletalMuscle9.6
Skin11.75
SmoothMuscle7.3
Spinalcord6.75
SubthalamicNucleus6.1
SuperiorCervicalGanglion8.8
TemporalLobe5.95
Testis5.45
TestisGermCell5.35
TestisIntersitial13.8
TestisLeydigCell6.55
TestisSeminiferousTubule5.8
Thalamus6.6
Thymus4.85
Thyroid7.7
Tongue7.05
Tonsil6.25
Trachea5.25
TrigeminalGanglion10.7
Uterus5.1
UterusCorpus6.05
WholeBlood6.95
Wholebrain5.05
colon7.35
pineal_day7.84
pineal_night7.7
retina7.65
small_intestine6.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14791_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.54 ± 0.4
Basal Forebrain6.02 ± 0.27
Basal Part of Pons5.48 ± 0.56
Cerebellar Cortex6.16 ± 0.31
Cerebellar Nuclei5.34 ± 0.4
Claustrum7.16 ± 0.62
Epithalamus5.67 ± 0.27
Frontal Lobe6.03 ± 0.43
Globus Pallidus5.71 ± 0.43
Hypothalamus6.24 ± 0.29
Insula6.37 ± 0.28
Limbic Lobe6.42 ± 0.63
Mesencephalon6.03 ± 0.53
Myelencephalon6.1 ± 0.51
Occipital Lobe5.91 ± 0.42
Parietal Lobe6 ± 0.49
Pontine Tegmentum6.25 ± 0.44
Striatum6.49 ± 0.44
Subthalamus5.95 ± 0.44
Temporal Lobe6.24 ± 0.52
Thalamus5.79 ± 0.4
White Matter4.59 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpd2CBCerebellum15.87
16.48
Gpd2CTXCerebral cortex86.01
65.14
Gpd2HIPHippocampal region82.74
100
Gpd2HPFHippocampal formation85.77
91.91
Gpd2HYHypothalamus13.09
9.72
Gpd2LSXLateral septal complex11.7
8.51
Gpd2MBMidbrain12.77
10.95
Gpd2MYMedulla17.68
16
Gpd2OLFOlfactory bulb55.08
43.03
Gpd2PPons17.08
14.35
Gpd2PALPallidum10.97
8.6
Gpd2RHPRetrohippocampal region90.9
80.09
Gpd2sAMYStriatum-like amygdalar nuclei26.75
20.11
Gpd2STRStriatum13.93
10.69
Gpd2STRdStriatum dorsal region12.18
9.82
Gpd2STRvStriatum ventral region12.28
8.2
Gpd2THThalamus9.3
8.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GPDM_HUMAN_144 22 144 165 ANLLEIAPHLSAPLPIMLPVYK PRIDE
GPDM_HUMAN_227 11 227 237 MNLAIALTAAR PRIDE
GPDM_HUMAN_238 16 238 253 YGAATANYMEVVSLLK PRIDE
GPDM_HUMAN_339 9 339 347 VIFFLPWQK PRIDE
GPDM_HUMAN_441 12 441 452 SMAEDTINAAVK PRIDE
GPDM_HUMAN_525 13 525 537 LVSEFPYIEAEVK PRIDE
GPDM_HUMAN_557 15 557 571 LAFLNVQAAEEALPR PRIDE
GPDM_HUMAN_94 16 94 109 TALVERDDFSSGTSSR PRIDE
PAp00001104 13 270 282 CKDVLTGQEFDVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018