AutismKB 2.0

Annotation Detail for MKX


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Basic Information Top
Gene Symbol:MKX ( C10orf48,IFRX,IRXL1,MGC39616 )
Gene Full Name: mohawk homeobox
Band: 10p12.1
Quick LinksEntrez ID:283078; OMIM: 601332; Uniprot ID:MKX_HUMAN; ENSEMBL ID: ENSG00000150051; HGNC ID: 23729
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal27 / 33603078
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain7 / 11009896
cervix0 / 481710 
connective tissue1 / 1492556
ear5 / 16212308
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P75002
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.84 ± 0.96
Basal Forebrain6.6 ± 0.72
Basal Part of Pons6.82 ± 0.3
Cerebellar Cortex5.07 ± 0.54
Cerebellar Nuclei7.03 ± 0.57
Claustrum5.6 ± 1.08
Epithalamus7 ± 0.94
Frontal Lobe6.03 ± 0.73
Globus Pallidus5.9 ± 0.74
Hypothalamus6.31 ± 0.62
Insula5.56 ± 0.59
Limbic Lobe5.15 ± 0.9
Mesencephalon6.01 ± 0.69
Myelencephalon5.81 ± 0.89
Occipital Lobe6.11 ± 0.61
Parietal Lobe6.62 ± 0.5
Pontine Tegmentum6.1 ± 0.67
Striatum5.13 ± 1.3
Subthalamus6.18 ± 0.84
Temporal Lobe6.17 ± 0.58
Thalamus5.48 ± 0.82
White Matter4.75 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MkxCBCerebellum0
0
MkxCTXCerebral cortex0
0
MkxHIPHippocampal region0
0
MkxHPFHippocampal formation0
0
MkxHYHypothalamus0
0
MkxLSXLateral septal complex0
0
MkxMBMidbrain0
0
MkxMYMedulla0
0
MkxOLFOlfactory bulb0
0
MkxPPons0
0
MkxPALPallidum0
0
MkxRHPRetrohippocampal region0
0
MkxsAMYStriatum-like amygdalar nuclei0
0
MkxSTRStriatum0
0
MkxSTRdStriatum dorsal region0
0
MkxSTRvStriatum ventral region0
0
MkxTHThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018