AutismKB 2.0

Annotation Detail for KCTD21


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Basic Information Top
Gene Symbol:KCTD21 ( - )
Gene Full Name: potassium channel tetramerisation domain containing 21
Band: 11q14.1
Quick LinksEntrez ID:283219; OMIM: NA; Uniprot ID:KCD21_HUMAN; ENSEMBL ID: ENSG00000188997; HGNC ID: 27452
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus13 / 56401223
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor11 / 13630280
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal91 / 336030727
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain66 / 110098959
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye6 / 21105428
heart0 / 896260 
intestine3 / 23447212
kidney3 / 21177714
larynx1 / 2414541
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth7 / 67052104
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta6 / 28082521
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen2 / 5395237
stomach1 / 9661910
testis14 / 33044242
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord2 / 13680146
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_19_PI416383280
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.17 ± 0.45
Basal Forebrain6.03 ± 0.51
Basal Part of Pons5.59 ± 0.35
Cerebellar Cortex5.53 ± 0.29
Cerebellar Nuclei6.31 ± 0.3
Claustrum6.57 ± 0.43
Epithalamus5.77 ± 0.38
Frontal Lobe5.79 ± 0.47
Globus Pallidus6.55 ± 0.23
Hypothalamus5.98 ± 0.43
Insula5.88 ± 0.38
Limbic Lobe5.9 ± 0.47
Mesencephalon6.15 ± 0.42
Myelencephalon5.91 ± 0.4
Occipital Lobe6 ± 0.35
Parietal Lobe5.89 ± 0.46
Pontine Tegmentum5.93 ± 0.41
Striatum5.99 ± 0.37
Subthalamus6.16 ± 0.19
Temporal Lobe5.83 ± 0.36
Thalamus6.04 ± 0.4
White Matter6.45 ± 0.59
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018