AutismKB 2.0

Annotation Detail for FAM177A1


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Basic Information Top
Gene Symbol:FAM177A1 ( C14orf24,DKFZp686J1254,FLJ38854 )
Gene Full Name: family with sequence similarity 177, member A1
Band: 14q13.2
Quick LinksEntrez ID:283635; OMIM: NA; Uniprot ID:F177A_HUMAN; ENSEMBL ID: ENSG00000151327; HGNC ID: 19829
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor8 / 26384530
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia11 / 97250113
normal120 / 336030735
ovarian tumor6 / 7668278
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites3 / 4001574
bladder3 / 29757100
blood2 / 12347816
bone2 / 7165527
bone marrow1 / 4880120
brain55 / 110098949
cervix0 / 481710 
connective tissue17 / 149255113
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart2 / 8962622
intestine9 / 23447238
kidney21 / 21177799
larynx2 / 2414582
liver4 / 20774319
lung19 / 33697456
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle3 / 10771527
nerve1 / 1576863
ovary6 / 10205158
pancreas9 / 21481241
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate7 / 18934536
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach4 / 9661941
testis19 / 33044257
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus14 / 23287860
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P2935
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.94 ± 0.62
Basal Forebrain5.06 ± 0.26
Basal Part of Pons4.82 ± 0.37
Cerebellar Cortex4.77 ± 0.35
Cerebellar Nuclei5.13 ± 0.38
Claustrum4.95 ± 0.76
Epithalamus4.53 ± 0.45
Frontal Lobe4.83 ± 0.48
Globus Pallidus5.9 ± 0.18
Hypothalamus5.21 ± 0.32
Insula4.65 ± 0.3
Limbic Lobe4.82 ± 0.44
Mesencephalon5 ± 0.59
Myelencephalon4.96 ± 0.47
Occipital Lobe5.05 ± 0.47
Parietal Lobe4.9 ± 0.48
Pontine Tegmentum4.99 ± 0.39
Striatum5.11 ± 0.44
Subthalamus5.12 ± 0.24
Temporal Lobe4.85 ± 0.43
Thalamus4.94 ± 0.4
White Matter6.31 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1700047I17RikCBCerebellum9.61
11.25
1700047I17RikCTXCerebral cortex7.29
4.76
1700047I17RikHIPHippocampal region4.97
4.44
1700047I17RikHPFHippocampal formation6.4
5.41
1700047I17RikHYHypothalamus1.89
1.66
1700047I17RikLSXLateral septal complex0.6
0.51
1700047I17RikMBMidbrain2.18
2.07
1700047I17RikMYMedulla9.28
9.82
1700047I17RikOLFOlfactory bulb6.73
6.03
1700047I17RikPPons2.71
2.52
1700047I17RikPALPallidum1.63
1.43
1700047I17RikRHPRetrohippocampal region8.93
6.76
1700047I17RiksAMYStriatum-like amygdalar nuclei1.3
1.02
1700047I17RikSTRStriatum2.48
1.8
1700047I17RikSTRdStriatum dorsal region3.36
2.38
1700047I17RikSTRvStriatum ventral region1.18
1.09
1700047I17RikTHThalamus3.9
2.95
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
F177A_HUMAN_1 11 1 11 MDQEPVGGVER PRIDE
PAp00039299 26 129 154 AATSTLSVCDFLGEKIASVLGISTPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018