AutismKB 2.0

Annotation Detail for PGP


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Basic Information Top
Gene Symbol:PGP ( MGC4692 )
Gene Full Name: phosphoglycolate phosphatase
Band: 16p13.3
Quick LinksEntrez ID:283871; OMIM: 172280; Uniprot ID:PGP_HUMAN; ENSEMBL ID: ENSG00000184207; HGNC ID: 8909
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma3 / 17475171
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma11 / 106883102
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal126 / 336030737
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor12 / 12494996
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain58 / 110098952
cervix6 / 48171124
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye10 / 21105447
heart0 / 896260 
intestine9 / 23447238
kidney4 / 21177718
larynx0 / 241450 
liver4 / 20774319
lung10 / 33697429
lymph2 / 4427045
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle6 / 10771555
nerve0 / 157680 
ovary1 / 1020519
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate6 / 18934531
salivary gland2 / 2015599
skin13 / 21057461
spleen0 / 539520 
stomach0 / 966190 
testis14 / 33044242
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218410_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte3.9
AdrenalCortex4.05
Adrenalgland3.3
Amygdala4.15
Appendix3.85
AtrioventricularNode2.95
BDCA4+_DentriticCells4.35
Bonemarrow3.85
BronchialEpithelialCells3.9
CD105+_Endothelial3.95
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.2
CD33+_Myeloid5.05
CD34+5
CD4+_Tcells4.3
CD56+_NKCells4.75
CD71+_EarlyErythroid3.65
CD8+_Tcells3.8
CardiacMyocytes4.9
Caudatenucleus3.5
Cerebellum3.15
CerebellumPeduncles4.45
CiliaryGanglion2.7
CingulateCortex4
Colorectaladenocarcinoma3.9
DorsalRootGanglion3.05
FetalThyroid3.8
Fetalbrain3.85
Fetalliver3.4
Fetallung3.25
GlobusPallidus2.85
Heart5.1
Hypothalamus4.25
Kidney3.2
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-603.45
Leukemialymphoblastic(MOLT-4)3.15
Liver5.25
Lung4.35
Lymphnode3.4
Lymphoma_burkitts(Daudi)5
Lymphoma_burkitts(Raji)5.45
MedullaOblongata3.8
OccipitalLobe3.5
OlfactoryBulb3.1
Ovary2.6
Pancreas3.15
PancreaticIslet4.2
ParietalLobe4.1
Pituitary4.55
Placenta4.1
Pons3.7
PrefrontalCortex4.95
Prostate4.6
Salivarygland3.1
SkeletalMuscle4.45
Skin3
SmoothMuscle4.45
Spinalcord4.15
SubthalamicNucleus3.55
SuperiorCervicalGanglion4.4
TemporalLobe3.55
Testis3.4
TestisGermCell3.3
TestisIntersitial3.25
TestisLeydigCell3.85
TestisSeminiferousTubule3.4
Thalamus4
Thymus3.1
Thyroid4.9
Tongue3.8
Tonsil3.8
Trachea3.3
TrigeminalGanglion5.25
Uterus3.2
UterusCorpus3.45
WholeBlood4.3
Wholebrain3.5
colon3.95
pineal_day4.92
pineal_night4.82
retina4.75
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P66100
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.83 ± 0.83
Basal Forebrain4.63 ± 0.34
Basal Part of Pons5.37 ± 0.34
Cerebellar Cortex5.21 ± 0.25
Cerebellar Nuclei5.07 ± 0.35
Claustrum5.17 ± 0.6
Epithalamus4.26 ± 0.66
Frontal Lobe4.86 ± 0.46
Globus Pallidus3.61 ± 0.8
Hypothalamus4.13 ± 0.45
Insula4.71 ± 0.45
Limbic Lobe4.91 ± 0.45
Mesencephalon4.69 ± 0.47
Myelencephalon4.74 ± 0.55
Occipital Lobe4.89 ± 0.47
Parietal Lobe4.91 ± 0.54
Pontine Tegmentum4.72 ± 0.49
Striatum4.37 ± 0.63
Subthalamus4.17 ± 0.31
Temporal Lobe4.79 ± 0.42
Thalamus4.67 ± 0.5
White Matter3.71 ± 0.47
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002440 10 211 220 FIAGTGCLVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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