AutismKB 2.0

Annotation Detail for ANGPT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ANGPT1 ( AGP1,AGPT,ANG1 )
Gene Full Name: angiopoietin 1
Band: 8q23.1
Quick LinksEntrez ID:284; OMIM: 601667; Uniprot ID:ANGP1_HUMAN; ENSEMBL ID: ENSG00000154188; HGNC ID: 484
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult30 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal78 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer7 / 10268068
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow15 / 48801307
brain15 / 110098913
cervix1 / 4817120
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye4 / 21105418
heart3 / 8962633
intestine2 / 2344728
kidney7 / 21177733
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth3 / 6705244
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate9 / 18934547
salivary gland3 / 20155148
skin2 / 2105749
spleen2 / 5395237
stomach1 / 9661910
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus4 / 23287817
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205608_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.3
Adipocyte3.4
AdrenalCortex3.7
Adrenalgland2.9
Amygdala3.65
Appendix3.7
AtrioventricularNode2.8
BDCA4+_DentriticCells3.9
Bonemarrow3.35
BronchialEpithelialCells3.35
CD105+_Endothelial3.5
CD14+_Monocytes3.7
CD19+_BCells(neg._sel.)3.7
CD33+_Myeloid4.5
CD34+40.35
CD4+_Tcells3.8
CD56+_NKCells4.15
CD71+_EarlyErythroid3.2
CD8+_Tcells3.3
CardiacMyocytes4.35
Caudatenucleus3.05
Cerebellum2.8
CerebellumPeduncles3.9
CiliaryGanglion2.5
CingulateCortex3.5
Colorectaladenocarcinoma3.45
DorsalRootGanglion2.7
FetalThyroid3.35
Fetalbrain3.5
Fetalliver2.95
Fetallung2.9
GlobusPallidus2.5
Heart4.3
Hypothalamus3.75
Kidney2.75
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-603
Leukemialymphoblastic(MOLT-4)2.8
Liver4.5
Lung3.8
Lymphnode2.95
Lymphoma_burkitts(Daudi)4.4
Lymphoma_burkitts(Raji)4.85
MedullaOblongata3.15
OccipitalLobe3.1
OlfactoryBulb2.75
Ovary2.25
Pancreas2.75
PancreaticIslet3.7
ParietalLobe3.65
Pituitary4.35
Placenta3.55
Pons3.25
PrefrontalCortex4.35
Prostate4.1
Salivarygland2.7
SkeletalMuscle4
Skin2.7
SmoothMuscle3.95
Spinalcord3.65
SubthalamicNucleus3.15
SuperiorCervicalGanglion4.05
TemporalLobe3.1
Testis3
TestisGermCell2.9
TestisIntersitial2.9
TestisLeydigCell3.45
TestisSeminiferousTubule3.05
Thalamus3.45
Thymus2.7
Thyroid4.35
Tongue3.4
Tonsil3.35
Trachea2.9
TrigeminalGanglion3.85
Uterus2.9
UterusCorpus3.1
WholeBlood3.85
Wholebrain2.95
colon3.45
pineal_day4.34
pineal_night4.22
retina4.525
small_intestine3.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P60887
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.05 ± 0.8
Basal Forebrain5.69 ± 0.69
Basal Part of Pons4.04 ± 0.57
Cerebellar Cortex5.58 ± 0.36
Cerebellar Nuclei5.91 ± 0.52
Claustrum4.63 ± 0.52
Epithalamus6.32 ± 0.67
Frontal Lobe5.03 ± 0.78
Globus Pallidus6.01 ± 0.96
Hypothalamus5.62 ± 0.6
Insula5.14 ± 0.54
Limbic Lobe5.04 ± 0.95
Mesencephalon5.16 ± 0.9
Myelencephalon5.2 ± 0.76
Occipital Lobe5.05 ± 0.83
Parietal Lobe4.7 ± 0.82
Pontine Tegmentum5.33 ± 0.44
Striatum4.53 ± 1.04
Subthalamus4.19 ± 0.47
Temporal Lobe4.72 ± 0.62
Thalamus4.7 ± 0.53
White Matter6.05 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Angpt1CBCerebellum0.84
1.01
Angpt1CTXCerebral cortex1.98
1.57
Angpt1HIPHippocampal region0.24
0.26
Angpt1HPFHippocampal formation1.5
1.29
Angpt1HYHypothalamus2.04
2.22
Angpt1LSXLateral septal complex0.13
0.07
Angpt1MBMidbrain0.82
0.97
Angpt1MYMedulla2.71
2.68
Angpt1OLFOlfactory bulb4.32
3.6
Angpt1PPons1.35
1.72
Angpt1PALPallidum0.3
0.26
Angpt1RHPRetrohippocampal region3.96
2.99
Angpt1sAMYStriatum-like amygdalar nuclei1.22
0.91
Angpt1STRStriatum0.38
0.31
Angpt1STRdStriatum dorsal region0.32
0.3
Angpt1STRvStriatum ventral region0.2
0.11
Angpt1THThalamus0.57
0.48
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved