AutismKB 2.0

Annotation Detail for METRNL


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Basic Information Top
Gene Symbol:METRNL ( MGC99788 )
Gene Full Name: meteorin, glial cell differentiation regulator-like
Band: 17q25.3
Quick LinksEntrez ID:284207; OMIM: NA; Uniprot ID:METRL_HUMAN; ENSEMBL ID: ENSG00000176845; HGNC ID: 27584
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma12 / 82823144
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal70 / 336030720
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood4 / 12347832
bone5 / 7165569
bone marrow1 / 4880120
brain19 / 110098917
cervix3 / 4817162
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye10 / 21105447
heart2 / 8962622
intestine8 / 23447234
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung11 / 33697432
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate4 / 18934521
salivary gland0 / 201550 
skin4 / 21057418
spleen5 / 5395292
stomach0 / 966190 
testis1 / 3304423
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_75_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 0.98
Basal Forebrain2.02 ± 0.43
Basal Part of Pons1.71 ± 0.47
Cerebellar Cortex2.66 ± 0.71
Cerebellar Nuclei2.48 ± 0.7
Claustrum2.58 ± 0.69
Epithalamus2.39 ± 0.63
Frontal Lobe2.27 ± 0.72
Globus Pallidus2.26 ± 0.71
Hypothalamus2.2 ± 0.79
Insula1.91 ± 0.7
Limbic Lobe2.07 ± 0.69
Mesencephalon2.35 ± 0.79
Myelencephalon2.25 ± 0.67
Occipital Lobe2.13 ± 0.84
Parietal Lobe2.19 ± 0.76
Pontine Tegmentum2.3 ± 0.8
Striatum2.28 ± 0.9
Subthalamus2.02 ± 0.8
Temporal Lobe2.13 ± 0.76
Thalamus2.5 ± 0.71
White Matter1.52 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MetrnlCBCerebellum4.04
5.67
MetrnlCTXCerebral cortex7.25
5.51
MetrnlHIPHippocampal region6.58
6.4
MetrnlHPFHippocampal formation9.1
8.1
MetrnlHYHypothalamus0.96
1.16
MetrnlLSXLateral septal complex0.67
0.63
MetrnlMBMidbrain1.96
2.25
MetrnlMYMedulla7.3
8.67
MetrnlOLFOlfactory bulb7.83
6.99
MetrnlPPons5.93
7.7
MetrnlPALPallidum0.96
1.13
MetrnlRHPRetrohippocampal region13.54
10.67
MetrnlsAMYStriatum-like amygdalar nuclei9.66
10.39
MetrnlSTRStriatum1.81
1.71
MetrnlSTRdStriatum dorsal region0.88
0.76
MetrnlSTRvStriatum ventral region1.9
1.41
MetrnlTHThalamus1.79
1.68
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018