AutismKB 2.0

Annotation Detail for LAMA1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LAMA1 ( LAMA )
Gene Full Name: laminin, alpha 1
Band: 18p11.31
Quick LinksEntrez ID:284217; OMIM: 150320; Uniprot ID:LAMA1_HUMAN; ENSEMBL ID: ENSG00000101680; HGNC ID: 6481
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult46 / 193912123
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor36 / 263845136
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal56 / 336030716
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal2 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine4 / 23447217
kidney5 / 21177723
larynx0 / 241450 
liver2 / 2077439
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis23 / 33044269
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: Primary tumors (U95A)
  • Affymatrix Probe ID: 728_at
Cell line Expression level Expression bar
Pr1T3.619
Pr4T4.437
Pr5T3.998
Pr7T4.188
Pr1N4.364
Pr5N4.164
Pr6T5.032
Pr3N4.2
Pr3T4.41
Pr4N4.108
Pr2N3.914
Pr8N4.22
Pr8T4.609
Pr9N4.126
Pr10N4.3
Pr10T4.448
Pr9T3.927
Pr11T4.292
Pr12T4.19
Pr13AT4.459
Pr13BT4.23
Pr21T4.297
Pr22T4.304
Pr30T4.936
Pr23T4.789
Pr19T4.566
Pr26T4.458
Pr31T4.431
Pr16T4.551
Pr17T4.496
Pr24T4.277
Pr27T3.985
Pr29T3.793
OVR1024.326
HUOVR4.13
G24.987
G34.7
G54.38
G64.479
G84.209
G94.467
CO7T4.866
CO8T4.255
CO15T5.168
CO27T4.789
CO30T5.038
CO32T4.58
CO40T4.495
CO52N5.442
CO62N5.025
K14.19
K24.258
K33.841
K44.453
K14N5.528
K164.576
K175.383
K194.545
K204.529
K224.465
CO9T4.487
CO20T5.153
CO24T4.947
CO36N5.292
K184.314
P1N4.13
P2N4.71
P5N4.971
P84.361
P113.639
P174.641
K214.779
K25N5.079
K28N5.522
CO42T4.8
P223.92
P13N4.277
LU11T4.548
LU16T4.847
LU7T4.308
LU8T4.325
LU12T4.542
LU13T4.82
LU5T4.826
LU6T5.302
LU14T4.659
LU17T4.818
LU50N4.143
LU52N4.683
LU18T4.576
LU55N4.87
LU3N5.169
P16B5.548
P234.238
OVR164.208
OVR194.168
OVR274.31
OVR284.28
OVR278E4.631
OVR24.333
OVR54.265
OVR84.67
OVR114.596
OVR124.588
OVR134.312
OVR224.736
OVR264.698
OVR105.287
OVR278S5.073
OVR14.491
LU19T4.449
LU20T4.536
LU24T4.598
LU25T4.606
LU31T5.305
LU34T4.884
LU39T3.942
CO14T4.843
CO21T5.431
CO23T4.871
CO41N4.387
LU40T5.232
LU41T4.209
LU44T4.687
LU46T4.641
LU49T4.674
L5N4.781
LU42T4.647
LU30T4.779
LU43T5.547
CO5T4.84
CO44T4.299
CO49T4.694
CO51T4.822
CO56T4.447
CO61T4.423
LU26T4.86
LU33T5.272
LU36T4.429
CO43T4.981
G184.948
G464.459
L11T5.29
L13N4.968
L30T5.112
L31T5.22
L32T5.451
L34T5.403
L35T5.568
B1N5.337
B5N4.542
B8T4.69
B10T4.626
B14T5.221
B16T4.543
B17T4.701
B1NR5.109
B20T5.715
B51NR5.189
B6T5.889
B15T6.118
B21T6.77
B29T4.758
B31T5.296
B32T5.573
B24T4.51
B46T4.511
B34T4.815
B36T4.721
B37T4.989
B38T4.735
B39T4.278
X1024.675
X116_024.696
G2804.257
X464.339
X584.228
G1864.88
G2964.598
L38T4.616
L31T.24.498
L26N5.002
N257ANTR4.762
N285BODY4.372
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P199126
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.54 ± 0.8
Basal Forebrain4.39 ± 0.4
Basal Part of Pons4.32 ± 0.71
Cerebellar Cortex3.83 ± 0.64
Cerebellar Nuclei4.12 ± 0.6
Claustrum4.62 ± 0.93
Epithalamus4.23 ± 0.9
Frontal Lobe4.28 ± 0.67
Globus Pallidus4.79 ± 0.72
Hypothalamus4.31 ± 0.51
Insula3.95 ± 0.99
Limbic Lobe4.35 ± 0.74
Mesencephalon4.35 ± 0.65
Myelencephalon4.35 ± 0.69
Occipital Lobe4.06 ± 0.75
Parietal Lobe4.22 ± 0.63
Pontine Tegmentum4.13 ± 0.78
Striatum4.59 ± 0.63
Subthalamus3.52 ± 1.66
Temporal Lobe4.21 ± 0.71
Thalamus4.42 ± 0.58
White Matter4.33 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lama1CBCerebellum8.67
9.33
Lama1CTXCerebral cortex3.8
2.93
Lama1HIPHippocampal region2.04
1.89
Lama1HPFHippocampal formation2.56
2.29
Lama1HYHypothalamus1.39
1.11
Lama1LSXLateral septal complex1.22
1.1
Lama1MBMidbrain1.65
2.08
Lama1MYMedulla6.34
7.02
Lama1OLFOlfactory bulb7.23
4.97
Lama1PPons6.6
6.03
Lama1PALPallidum1.76
1.5
Lama1RHPRetrohippocampal region3.47
2.84
Lama1sAMYStriatum-like amygdalar nuclei3.11
2.44
Lama1STRStriatum2.25
1.81
Lama1STRdStriatum dorsal region2.18
1.83
Lama1STRvStriatum ventral region2.56
1.78
Lama1THThalamus1.56
1.48
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved