AutismKB 2.0

Annotation Detail for ZADH2


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Basic Information Top
Gene Symbol:ZADH2 ( MGC45594 )
Gene Full Name: zinc binding alcohol dehydrogenase domain containing 2
Band: 18q22.3
Quick LinksEntrez ID:284273; OMIM: NA; Uniprot ID:ZADH2_HUMAN; ENSEMBL ID: ENSG00000180011; HGNC ID: 28697
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal130 / 336030738
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone3 / 7165541
bone marrow1 / 4880120
brain25 / 110098922
cervix1 / 4817120
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye8 / 21105437
heart6 / 8962666
intestine4 / 23447217
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung19 / 33697456
lymph1 / 4427022
lymph node8 / 9161087
mammary gland6 / 15327139
mouth2 / 6705229
muscle7 / 10771564
nerve1 / 1576863
ovary1 / 1020519
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta9 / 28082532
prostate10 / 18934552
salivary gland2 / 2015599
skin15 / 21057471
spleen3 / 5395255
stomach2 / 9661920
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P22746
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.53 ± 0.68
Basal Forebrain7.07 ± 0.48
Basal Part of Pons7.56 ± 0.36
Cerebellar Cortex7.41 ± 0.22
Cerebellar Nuclei6.8 ± 0.79
Claustrum6.29 ± 0.66
Epithalamus6.32 ± 0.53
Frontal Lobe7.03 ± 0.42
Globus Pallidus5.93 ± 0.34
Hypothalamus6.83 ± 0.4
Insula7.1 ± 0.36
Limbic Lobe6.66 ± 0.65
Mesencephalon6.78 ± 0.47
Myelencephalon6.84 ± 0.62
Occipital Lobe7.04 ± 0.49
Parietal Lobe7.07 ± 0.62
Pontine Tegmentum6.78 ± 0.49
Striatum6.47 ± 0.44
Subthalamus7.02 ± 0.88
Temporal Lobe7.03 ± 0.43
Thalamus6.98 ± 0.48
White Matter5.6 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zadh2CBCerebellum21.71
26.77
Zadh2CTXCerebral cortex42.89
29.49
Zadh2HIPHippocampal region17.33
18.87
Zadh2HPFHippocampal formation22.09
19.92
Zadh2HYHypothalamus10.2
7.56
Zadh2LSXLateral septal complex16.03
10.43
Zadh2MBMidbrain18.14
15.85
Zadh2MYMedulla30.17
30.52
Zadh2OLFOlfactory bulb47.57
39.78
Zadh2PPons23.63
23.38
Zadh2PALPallidum11.19
8.81
Zadh2RHPRetrohippocampal region29.04
21.14
Zadh2sAMYStriatum-like amygdalar nuclei8.91
5.87
Zadh2STRStriatum21.57
15.4
Zadh2STRdStriatum dorsal region19.38
13.96
Zadh2STRvStriatum ventral region36.05
24.72
Zadh2THThalamus12.03
9.54
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018