AutismKB 2.0

Annotation Detail for HKR1


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Basic Information Top
Gene Symbol:HKR1 ( ZNF875 )
Gene Full Name: HKR1, GLI-Kruppel zinc finger family member
Band: 19q13.13
Quick LinksEntrez ID:284459; OMIM: 165250; Uniprot ID:HKR1_HUMAN; ENSEMBL ID: ENSG00000181666; HGNC ID: 4928
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult73 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor22 / 26384583
glioma1 / 1068839
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal135 / 336030740
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma6 / 46356129
skin tumor6 / 12494948
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain50 / 110098945
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye22 / 211054104
heart0 / 896260 
intestine7 / 23447229
kidney12 / 21177756
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node2 / 9161021
mammary gland8 / 15327152
mouth7 / 67052104
muscle5 / 10771546
nerve0 / 157680 
ovary5 / 10205148
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta6 / 28082521
prostate8 / 18934542
salivary gland0 / 201550 
skin6 / 21057428
spleen8 / 53952148
stomach3 / 9661931
testis15 / 33044245
thymus8 / 8113198
thyroid8 / 47473168
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2354_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.91 ± 0.54
Basal Forebrain6.81 ± 0.24
Basal Part of Pons6.71 ± 0.32
Cerebellar Cortex6.85 ± 0.39
Cerebellar Nuclei6.86 ± 0.22
Claustrum7.09 ± 0.63
Epithalamus6.61 ± 0.28
Frontal Lobe6.71 ± 0.39
Globus Pallidus6.91 ± 0.2
Hypothalamus6.65 ± 0.23
Insula6.67 ± 0.21
Limbic Lobe7 ± 0.42
Mesencephalon6.87 ± 0.44
Myelencephalon6.82 ± 0.38
Occipital Lobe7.26 ± 0.45
Parietal Lobe6.88 ± 0.35
Pontine Tegmentum6.83 ± 0.33
Striatum6.81 ± 0.44
Subthalamus6.34 ± 0.18
Temporal Lobe6.72 ± 0.35
Thalamus6.94 ± 0.31
White Matter7.02 ± 0.33
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018