AutismKB 2.0

Annotation Detail for PRRT3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PRRT3 ( FLJ33674,MGC105134,MGC33990 )
Gene Full Name: proline-rich transmembrane protein 3
Band: 3p25.3
Quick LinksEntrez ID:285368; OMIM: NA; Uniprot ID:PRRT3_HUMAN; ENSEMBL ID: ENSG00000163704; HGNC ID: 26591
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult12 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal38 / 336030711
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain15 / 110098913
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary4 / 10205139
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate4 / 18934521
salivary gland1 / 2015549
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5374_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.82 ± 0.86
Basal Forebrain2.26 ± 0.3
Basal Part of Pons2.66 ± 0.88
Cerebellar Cortex3.02 ± 0.52
Cerebellar Nuclei2.74 ± 0.62
Claustrum2.93 ± 1.08
Epithalamus2.19 ± 0.72
Frontal Lobe2.54 ± 0.74
Globus Pallidus2.2 ± 0.9
Hypothalamus2.28 ± 0.65
Insula2.76 ± 0.57
Limbic Lobe2.58 ± 0.86
Mesencephalon2.62 ± 0.84
Myelencephalon2.6 ± 0.74
Occipital Lobe2.68 ± 0.72
Parietal Lobe2.73 ± 0.81
Pontine Tegmentum2.58 ± 0.62
Striatum2.25 ± 0.84
Subthalamus2.5 ± 0.56
Temporal Lobe2.58 ± 0.74
Thalamus2.45 ± 0.6
White Matter1.9 ± 0.9
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prrt3CBCerebellum19.74
31.7
Prrt3CTXCerebral cortex50
42.81
Prrt3HIPHippocampal region26.76
50
Prrt3HPFHippocampal formation34.02
47.19
Prrt3HYHypothalamus6.49
5.52
Prrt3LSXLateral septal complex2.13
1.59
Prrt3MBMidbrain16.96
15.54
Prrt3MYMedulla22.26
27.13
Prrt3OLFOlfactory bulb28.39
24.11
Prrt3PPons19.62
23.21
Prrt3PALPallidum12.92
12.11
Prrt3RHPRetrohippocampal region50
44.44
Prrt3sAMYStriatum-like amygdalar nuclei11.9
8.49
Prrt3STRStriatum17.17
12.28
Prrt3STRdStriatum dorsal region19.63
13.99
Prrt3STRvStriatum ventral region18.56
13.15
Prrt3THThalamus26.28
23.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00061065 24 77 100 HAPAEEMPEKPVASPLGPALYGPK Peptide Atlas
PRRT3_HUMAN_292 17 292 308 AGAEVSWEVSSPGPPPK PRIDE
PRRT3_HUMAN_309 8 309 316 QADLPDAK PRIDE
PRRT3_HUMAN_341 13 341 353 AAMNGADPISPQR PRIDE
PRRT3_HUMAN_49 18 49 66 GSVGSEPQAFDVFPENPR PRIDE
PRRT3_HUMAN_630 9 630 638 GWDASPGPR PRIDE
PRRT3_HUMAN_671 13 671 683 FSWAWWGVHFWLR PRIDE
PRRT3_HUMAN_882 28 882 909 GPVPQHVVEAPDGAAAAASGSSLDSFSR PRIDE
PRRT3_HUMAN_914 7 914 920 ISWNPWR PRIDE
PRRT3_HUMAN_966 7 966 972 GKPGESR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018