AutismKB 2.0

Annotation Detail for GPRIN3


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Basic Information Top
Gene Symbol:GPRIN3 ( FLJ42625,GRIN3 )
Gene Full Name: GPRIN family member 3
Band: 4q22.1
Quick LinksEntrez ID:285513; OMIM: 611241; Uniprot ID:GRIN3_HUMAN; ENSEMBL ID: ENSG00000185477; HGNC ID: 27733
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal19 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain15 / 110098913
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node3 / 9161032
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_390_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.61 ± 0.86
Basal Forebrain3.76 ± 0.85
Basal Part of Pons3.49 ± 0.68
Cerebellar Cortex4.61 ± 0.38
Cerebellar Nuclei4.57 ± 0.56
Claustrum3.41 ± 0.52
Epithalamus3.76 ± 0.52
Frontal Lobe3.79 ± 0.62
Globus Pallidus3.74 ± 0.95
Hypothalamus3.86 ± 0.56
Insula4.17 ± 0.48
Limbic Lobe4.11 ± 0.67
Mesencephalon4.08 ± 0.66
Myelencephalon4.02 ± 0.7
Occipital Lobe4.28 ± 0.68
Parietal Lobe3.77 ± 0.88
Pontine Tegmentum3.85 ± 0.72
Striatum4.78 ± 0.88
Subthalamus4.64 ± 0.24
Temporal Lobe3.75 ± 0.63
Thalamus3.79 ± 0.79
White Matter3.09 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gprin3CBCerebellum2.19
3.52
Gprin3CTXCerebral cortex6.42
5.26
Gprin3HIPHippocampal region3.29
3.18
Gprin3HPFHippocampal formation3.48
3.18
Gprin3HYHypothalamus0.63
0.54
Gprin3LSXLateral septal complex12.28
12.69
Gprin3MBMidbrain1.04
1.02
Gprin3MYMedulla2.98
2.82
Gprin3OLFOlfactory bulb6.53
5.41
Gprin3PPons1.36
1.31
Gprin3PALPallidum11.81
12.36
Gprin3RHPRetrohippocampal region3.56
2.98
Gprin3sAMYStriatum-like amygdalar nuclei4.73
3.3
Gprin3STRStriatum86.26
83.99
Gprin3STRdStriatum dorsal region94.83
91.08
Gprin3STRvStriatum ventral region89.19
88.14
Gprin3THThalamus1.43
1.39
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018