AutismKB 2.0

Annotation Detail for FRYL


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Basic Information Top
Gene Symbol:FRYL ( DKFZp686E205,FLJ16177,KIAA0826 )
Gene Full Name: FRY-like
Band: 4p11
Quick LinksEntrez ID:285527; OMIM: NA; Uniprot ID:FRYL_HUMAN; ENSEMBL ID: ENSG00000075539; HGNC ID: 29127
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus29 / 56401251
neonate1 / 3109732
infant2 / 2362084
juvenile1 / 5555617
adult102 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor14 / 114246122
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor6 / 26384522
glioma2 / 10688318
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal179 / 336030753
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites1 / 4001524
bladder2 / 2975767
blood3 / 12347824
bone3 / 7165541
bone marrow4 / 4880181
brain50 / 110098945
cervix0 / 481710 
connective tissue3 / 14925520
ear8 / 16212493
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye14 / 21105466
heart5 / 8962655
intestine25 / 234472106
kidney10 / 21177747
larynx0 / 241450 
liver8 / 20774338
lung12 / 33697435
lymph1 / 4427022
lymph node10 / 91610109
mammary gland9 / 15327158
mouth4 / 6705259
muscle5 / 10771546
nerve2 / 15768126
ovary1 / 1020519
pancreas13 / 21481260
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate7 / 18934536
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach5 / 9661951
testis9 / 33044227
thymus10 / 81131123
thyroid5 / 47473105
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord1 / 1368073
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212546_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts78
Adipocyte9.05
AdrenalCortex11.25
Adrenalgland7.3
Amygdala24.1
Appendix12
AtrioventricularNode9.7
BDCA4+_DentriticCells71.95
Bonemarrow9.05
BronchialEpithelialCells28
CD105+_Endothelial25.7
CD14+_Monocytes47.25
CD19+_BCells(neg._sel.)62.75
CD33+_Myeloid84.5
CD34+73.45
CD4+_Tcells158.95
CD56+_NKCells96.75
CD71+_EarlyErythroid316.7
CD8+_Tcells121.75
CardiacMyocytes15.55
Caudatenucleus35.9
Cerebellum7.8
CerebellumPeduncles11.25
CiliaryGanglion8.05
CingulateCortex35.55
Colorectaladenocarcinoma10.25
DorsalRootGanglion10.8
FetalThyroid9.65
Fetalbrain10.8
Fetalliver15.5
Fetallung14.15
GlobusPallidus9.75
Heart11.5
Hypothalamus119.05
Kidney7.6
Leukemia_chronicMyelogenousK-5629.35
Leukemia_promyelocytic-HL-609.95
Leukemialymphoblastic(MOLT-4)38.45
Liver12.25
Lung8.75
Lymphnode17.9
Lymphoma_burkitts(Daudi)21.35
Lymphoma_burkitts(Raji)15
MedullaOblongata40.35
OccipitalLobe56.9
OlfactoryBulb39.45
Ovary5.85
Pancreas10.7
PancreaticIslet14.1
ParietalLobe56.8
Pituitary18.2
Placenta8.4
Pons16.3
PrefrontalCortex191
Prostate12.15
Salivarygland13.4
SkeletalMuscle11.15
Skin10.25
SmoothMuscle17.85
Spinalcord54.85
SubthalamicNucleus13.85
SuperiorCervicalGanglion12.1
TemporalLobe9.85
Testis5.4
TestisGermCell14.9
TestisIntersitial17.55
TestisLeydigCell10.8
TestisSeminiferousTubule8.25
Thalamus25.4
Thymus7.45
Thyroid14.45
Tongue10.15
Tonsil29.7
Trachea12.8
TrigeminalGanglion12.95
Uterus12.9
UterusCorpus8.95
WholeBlood28.05
Wholebrain9.95
colon81.5
pineal_day43.52
pineal_night42.56
retina59.05
small_intestine10.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P187131
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.54 ± 0.31
Basal Forebrain9.02 ± 0.39
Basal Part of Pons8.84 ± 0.3
Cerebellar Cortex8.9 ± 0.17
Cerebellar Nuclei9.6 ± 0.39
Claustrum8.91 ± 0.33
Epithalamus8.92 ± 0.57
Frontal Lobe8.94 ± 0.47
Globus Pallidus10.01 ± 0.3
Hypothalamus8.78 ± 0.32
Insula8.77 ± 0.24
Limbic Lobe8.64 ± 0.37
Mesencephalon9.09 ± 0.5
Myelencephalon8.98 ± 0.47
Occipital Lobe8.9 ± 0.35
Parietal Lobe8.9 ± 0.47
Pontine Tegmentum9.07 ± 0.42
Striatum9.18 ± 0.46
Subthalamus9.33 ± 0.56
Temporal Lobe8.82 ± 0.37
Thalamus9.28 ± 0.33
White Matter11.09 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
FrylCBCerebellum28.53
37.64
FrylCTXCerebral cortex52.13
38.11
FrylHIPHippocampal region42.18
51.62
FrylHPFHippocampal formation47.15
47.08
FrylHYHypothalamus26.69
20.54
FrylLSXLateral septal complex38.92
27.79
FrylMBMidbrain41.29
37.98
FrylMYMedulla47.89
53.08
FrylOLFOlfactory bulb66.89
59.62
FrylPPons41.1
42.9
FrylPALPallidum31.44
26.46
FrylRHPRetrohippocampal region54.37
41.76
FrylsAMYStriatum-like amygdalar nuclei27.94
19.82
FrylSTRStriatum32.32
23.67
FrylSTRdStriatum dorsal region29.01
21.6
FrylSTRvStriatum ventral region41.83
29.11
FrylTHThalamus94.75
89.8
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00062975 18 2896 2913 AAQTTIETAIHSLIETLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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