AutismKB 2.0

Annotation Detail for SREK1IP1


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Basic Information Top
Gene Symbol:SREK1IP1 ( FLJ36754,MGC131910,MGC150548,MGC150549,P18SRP,SFRS12IP1 )
Gene Full Name: SREK1-interacting protein 1
Band: 5q12.3
Quick LinksEntrez ID:285672; OMIM: NA; Uniprot ID:SR1IP_HUMAN; ENSEMBL ID: ENSG00000153006; HGNC ID: 26716
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor13 / 26384549
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal100 / 336030729
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain7 / 11009896
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine5 / 23447221
kidney10 / 21177747
larynx0 / 241450 
liver6 / 20774328
lung9 / 33697426
lymph1 / 4427022
lymph node8 / 9161087
mammary gland4 / 15327126
mouth2 / 6705229
muscle5 / 10771546
nerve0 / 157680 
ovary2 / 10205119
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta7 / 28082524
prostate8 / 18934542
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217608_at
Cell line Expression level Expression bar
721_B_lymphoblasts29.6
Adipocyte11.25
AdrenalCortex20.6
Adrenalgland10.75
Amygdala15.95
Appendix27.25
AtrioventricularNode17.65
BDCA4+_DentriticCells42.2
Bonemarrow14.25
BronchialEpithelialCells15.35
CD105+_Endothelial27.5
CD14+_Monocytes19.3
CD19+_BCells(neg._sel.)64.6
CD33+_Myeloid74.65
CD34+45
CD4+_Tcells53.15
CD56+_NKCells41.7
CD71+_EarlyErythroid17.1
CD8+_Tcells71.55
CardiacMyocytes34.05
Caudatenucleus10.2
Cerebellum9.35
CerebellumPeduncles18.2
CiliaryGanglion14.5
CingulateCortex13.25
Colorectaladenocarcinoma25.6
DorsalRootGanglion14.75
FetalThyroid12.65
Fetalbrain11.6
Fetalliver10.95
Fetallung8.1
GlobusPallidus10.15
Heart27.75
Hypothalamus11.3
Kidney11.3
Leukemia_chronicMyelogenousK-5629.8
Leukemia_promyelocytic-HL-609.45
Leukemialymphoblastic(MOLT-4)9.3
Liver22.6
Lung12.2
Lymphnode9
Lymphoma_burkitts(Daudi)16.3
Lymphoma_burkitts(Raji)29.7
MedullaOblongata9.1
OccipitalLobe10.9
OlfactoryBulb9.45
Ovary9.85
Pancreas12.95
PancreaticIslet13.45
ParietalLobe14.65
Pituitary15.9
Placenta10.4
Pons12.85
PrefrontalCortex16.65
Prostate14.05
Salivarygland10.55
SkeletalMuscle27.65
Skin14.55
SmoothMuscle13.9
Spinalcord11.7
SubthalamicNucleus13.15
SuperiorCervicalGanglion25.4
TemporalLobe11.85
Testis9.9
TestisGermCell9.45
TestisIntersitial10.5
TestisLeydigCell13.4
TestisSeminiferousTubule10.1
Thalamus13.2
Thymus7.85
Thyroid16.75
Tongue15.95
Tonsil12.8
Trachea9.75
TrigeminalGanglion19.65
Uterus13.05
UterusCorpus17.45
WholeBlood13.6
Wholebrain9.4
colon11.95
pineal_day56.74
pineal_night51.78
retina15
small_intestine10.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P413184
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.03 ± 0.19
Basal Forebrain9.11 ± 0.18
Basal Part of Pons8.92 ± 0.17
Cerebellar Cortex9.24 ± 0.19
Cerebellar Nuclei8.88 ± 0.13
Claustrum9.22 ± 0.16
Epithalamus9.41 ± 0.31
Frontal Lobe9.09 ± 0.23
Globus Pallidus9.08 ± 0.24
Hypothalamus9.09 ± 0.22
Insula9.2 ± 0.23
Limbic Lobe9.06 ± 0.32
Mesencephalon9.02 ± 0.25
Myelencephalon9.05 ± 0.26
Occipital Lobe8.88 ± 0.23
Parietal Lobe9.03 ± 0.2
Pontine Tegmentum9.09 ± 0.21
Striatum9.27 ± 0.29
Subthalamus8.93 ± 0.24
Temporal Lobe9.08 ± 0.21
Thalamus9 ± 0.19
White Matter10 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
3110031B13RikCBCerebellum12.13
13.13
3110031B13RikCTXCerebral cortex17.65
12.21
3110031B13RikHIPHippocampal region17.72
16.66
3110031B13RikHPFHippocampal formation19.18
16.61
3110031B13RikHYHypothalamus1.41
1.13
3110031B13RikLSXLateral septal complex4.42
3.23
3110031B13RikMBMidbrain4.36
4.12
3110031B13RikMYMedulla7.01
7.1
3110031B13RikOLFOlfactory bulb11.97
8.8
3110031B13RikPPons4.98
4.77
3110031B13RikPALPallidum5.92
5.1
3110031B13RikRHPRetrohippocampal region21.2
16.16
3110031B13RiksAMYStriatum-like amygdalar nuclei7.48
5.31
3110031B13RikSTRStriatum8.2
5.75
3110031B13RikSTRdStriatum dorsal region8.55
5.98
3110031B13RikSTRvStriatum ventral region8.71
5.99
3110031B13RikTHThalamus10.05
8.36
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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