AutismKB 2.0

Annotation Detail for GPR34


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Basic Information Top
Gene Symbol:GPR34 ( - )
Gene Full Name: G protein-coupled receptor 34
Band: Xp11.4
Quick LinksEntrez ID:2857; OMIM: 300241; Uniprot ID:GPR34_HUMAN; ENSEMBL ID: ENSG00000171659; HGNC ID: 4490
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal50 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung1 / 3369742
lymph0 / 442700 
lymph node3 / 9161032
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta19 / 28082567
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis2 / 3304426
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P11201
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.09 ± 0.86
Basal Forebrain3.68 ± 0.96
Basal Part of Pons4.62 ± 0.59
Cerebellar Cortex3.11 ± 0.64
Cerebellar Nuclei5.41 ± 0.46
Claustrum3.47 ± 0.99
Epithalamus5.09 ± 0.63
Frontal Lobe3.85 ± 0.92
Globus Pallidus5.91 ± 0.44
Hypothalamus3.89 ± 1.61
Insula4.31 ± 0.66
Limbic Lobe3.67 ± 0.79
Mesencephalon4.03 ± 1.09
Myelencephalon3.93 ± 0.92
Occipital Lobe2.92 ± 0.96
Parietal Lobe3.86 ± 0.9
Pontine Tegmentum3.62 ± 0.66
Striatum4.47 ± 0.55
Subthalamus4.18 ± 0.63
Temporal Lobe4.12 ± 0.72
Thalamus3.87 ± 0.8
White Matter5.64 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr34CBCerebellum1.94
3.08
Gpr34CTXCerebral cortex4.59
3.39
Gpr34HIPHippocampal region1.69
1.66
Gpr34HPFHippocampal formation1.53
1.51
Gpr34HYHypothalamus0.75
0.48
Gpr34LSXLateral septal complex0.49
0.3
Gpr34MBMidbrain1.39
1.57
Gpr34MYMedulla2.46
2.64
Gpr34OLFOlfactory bulb6.55
4.32
Gpr34PPons2.03
2.6
Gpr34PALPallidum1.22
1.02
Gpr34RHPRetrohippocampal region1.19
0.97
Gpr34sAMYStriatum-like amygdalar nuclei0.83
0.5
Gpr34STRStriatum1.96
1.2
Gpr34STRdStriatum dorsal region1.73
1.13
Gpr34STRvStriatum ventral region3.91
2.07
Gpr34THThalamus1.32
1.14
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GPR34_HUMAN_241 7 241 247 IGKNLLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018