AutismKB 2.0

Annotation Detail for DPY19L4


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Basic Information Top
Gene Symbol:DPY19L4 ( MGC131885 )
Gene Full Name: dpy-19-like 4 (C. elegans)
Band: 8q22.1
Quick LinksEntrez ID:286148; OMIM: NA; Uniprot ID:D19L4_HUMAN; ENSEMBL ID: ENSG00000156162; HGNC ID: 27829
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult71 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma4 / 10688337
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal90 / 336030726
ovarian tumor7 / 7668291
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue3 / 14925520
ear4 / 16212246
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye8 / 21105437
heart2 / 8962622
intestine6 / 23447225
kidney7 / 21177733
larynx0 / 241450 
liver9 / 20774343
lung8 / 33697423
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary5 / 10205148
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta11 / 28082539
prostate8 / 18934542
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach3 / 9661931
testis9 / 33044227
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213391_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.15
Adipocyte4.65
AdrenalCortex4.2
Adrenalgland3.45
Amygdala4.15
Appendix6.35
AtrioventricularNode3.1
BDCA4+_DentriticCells4.55
Bonemarrow3.95
BronchialEpithelialCells4.15
CD105+_Endothelial4.05
CD14+_Monocytes4.25
CD19+_BCells(neg._sel.)4.25
CD33+_Myeloid5.1
CD34+8.45
CD4+_Tcells4.35
CD56+_NKCells4.75
CD71+_EarlyErythroid3.75
CD8+_Tcells4.2
CardiacMyocytes5.2
Caudatenucleus3.55
Cerebellum3.2
CerebellumPeduncles4.55
CiliaryGanglion2.8
CingulateCortex4.1
Colorectaladenocarcinoma4.05
DorsalRootGanglion3.1
FetalThyroid4
Fetalbrain3.95
Fetalliver3.45
Fetallung3.9
GlobusPallidus2.95
Heart5.05
Hypothalamus4.55
Kidney3.25
Leukemia_chronicMyelogenousK-5623.6
Leukemia_promyelocytic-HL-603.5
Leukemialymphoblastic(MOLT-4)4.45
Liver5.3
Lung4.35
Lymphnode3.4
Lymphoma_burkitts(Daudi)5.1
Lymphoma_burkitts(Raji)5.65
MedullaOblongata3.65
OccipitalLobe3.55
OlfactoryBulb3.3
Ovary2.9
Pancreas4.5
PancreaticIslet4.25
ParietalLobe4.25
Pituitary4.7
Placenta4.2
Pons3.8
PrefrontalCortex4.95
Prostate4.65
Salivarygland3.2
SkeletalMuscle4.65
Skin3.1
SmoothMuscle7
Spinalcord4.3
SubthalamicNucleus3.65
SuperiorCervicalGanglion5.55
TemporalLobe3.65
Testis3.4
TestisGermCell3.4
TestisIntersitial3.4
TestisLeydigCell3.95
TestisSeminiferousTubule3.4
Thalamus4.1
Thymus3.1
Thyroid8.5
Tongue3.95
Tonsil3.9
Trachea3.45
TrigeminalGanglion4.05
Uterus3.35
UterusCorpus3.6
WholeBlood4.3
Wholebrain3.35
colon4.05
pineal_day8.8
pineal_night5.98
retina4.85
small_intestine3.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P481824
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.13 ± 1.17
Basal Forebrain2.56 ± 0.67
Basal Part of Pons2.53 ± 0.65
Cerebellar Cortex2.39 ± 0.46
Cerebellar Nuclei3.46 ± 0.62
Claustrum2.76 ± 0.93
Epithalamus3.3 ± 0.65
Frontal Lobe2.85 ± 0.72
Globus Pallidus4.26 ± 0.37
Hypothalamus2.92 ± 0.68
Insula2.63 ± 0.76
Limbic Lobe2.73 ± 0.67
Mesencephalon2.94 ± 0.58
Myelencephalon2.83 ± 0.75
Occipital Lobe2.93 ± 0.62
Parietal Lobe2.83 ± 0.77
Pontine Tegmentum2.99 ± 0.62
Striatum3.01 ± 0.71
Subthalamus2.77 ± 0.79
Temporal Lobe2.61 ± 0.72
Thalamus2.99 ± 0.57
White Matter4.53 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dpy19l4CBCerebellum2.48
2.56
Dpy19l4CTXCerebral cortex0.38
0.35
Dpy19l4HIPHippocampal region0.47
1.14
Dpy19l4HPFHippocampal formation0.52
0.95
Dpy19l4HYHypothalamus0.21
0.26
Dpy19l4LSXLateral septal complex0.11
0.08
Dpy19l4MBMidbrain0.35
0.59
Dpy19l4MYMedulla2.6
3.57
Dpy19l4OLFOlfactory bulb0.58
0.81
Dpy19l4PPons1.11
1.42
Dpy19l4PALPallidum0.65
0.55
Dpy19l4RHPRetrohippocampal region0.48
0.6
Dpy19l4sAMYStriatum-like amygdalar nuclei1.58
1.68
Dpy19l4STRStriatum0.41
0.39
Dpy19l4STRdStriatum dorsal region0.28
0.26
Dpy19l4STRvStriatum ventral region0.39
0.31
Dpy19l4THThalamus0.41
0.43
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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