AutismKB 2.0

Annotation Detail for TUSC1


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Basic Information Top
Gene Symbol:TUSC1 ( MGC131751,TSG-9,TSG9 )
Gene Full Name: tumor suppressor candidate 1
Band: 9p21.2
Quick LinksEntrez ID:286319; OMIM: 610529; Uniprot ID:TUSC1_HUMAN; ENSEMBL ID: ENSG00000198680; HGNC ID: 31010
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal36 / 336030710
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta2 / 2808257
prostate6 / 18934531
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P133884
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.87 ± 0.42
Basal Forebrain7.02 ± 0.26
Basal Part of Pons7.56 ± 0.28
Cerebellar Cortex7.34 ± 0.17
Cerebellar Nuclei6.8 ± 0.34
Claustrum6.96 ± 0.48
Epithalamus7.18 ± 0.22
Frontal Lobe7.27 ± 0.26
Globus Pallidus6.3 ± 0.27
Hypothalamus7.55 ± 0.36
Insula7.35 ± 0.26
Limbic Lobe7.08 ± 0.42
Mesencephalon7.08 ± 0.39
Myelencephalon7.12 ± 0.43
Occipital Lobe6.92 ± 0.33
Parietal Lobe7.12 ± 0.34
Pontine Tegmentum7.04 ± 0.25
Striatum6.61 ± 0.42
Subthalamus7.05 ± 0.21
Temporal Lobe7.26 ± 0.29
Thalamus7.11 ± 0.27
White Matter6.96 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tusc1CBCerebellum24.71
30.33
Tusc1CTXCerebral cortex57.36
43.25
Tusc1HIPHippocampal region37.2
44.86
Tusc1HPFHippocampal formation40.26
43.32
Tusc1HYHypothalamus14.71
11.67
Tusc1LSXLateral septal complex4.83
3.11
Tusc1MBMidbrain22.54
19.47
Tusc1MYMedulla22.11
22.31
Tusc1OLFOlfactory bulb46.85
41.27
Tusc1PPons27.14
26.52
Tusc1PALPallidum19.09
15.84
Tusc1RHPRetrohippocampal region45.61
41.45
Tusc1sAMYStriatum-like amygdalar nuclei45.47
32.16
Tusc1STRStriatum27.44
19.83
Tusc1STRdStriatum dorsal region29.21
21.59
Tusc1STRvStriatum ventral region23.52
15.44
Tusc1THThalamus28.46
24.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499936 13 65 77 FADLAASHLEAIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018