AutismKB 2.0

Annotation Detail for GPX1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GPX1 ( GSHPX1,MGC14399,MGC88245 )
Gene Full Name: glutathione peroxidase 1
Band: 3p21.31
Quick LinksEntrez ID:2876; OMIM: 138320; Uniprot ID:GPX1_HUMAN; ENSEMBL ID: ENSG00000233276; HGNC ID: 4553
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst9 / 62319144
fetus48 / 56401285
neonate13 / 31097418
infant0 / 236200 
juvenile4 / 5555671
adult225 / 1939121116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor10 / 34366290
chondrosarcoma21 / 82823253
colorectal tumor7 / 11424661
esophageal tumor4 / 17290231
gastrointestinal tumor36 / 119369301
germ cell tumor29 / 263845109
glioma13 / 106883121
head and neck tumor20 / 136302146
kidney tumor10 / 68959145
leukemia7 / 9584273
liver tumor33 / 96359342
lung tumor26 / 103127252
lymphoma9 / 71755125
non-neoplasia7 / 9725071
normal400 / 3360307119
ovarian tumor14 / 76682182
pancreatic tumor21 / 104616200
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer11 / 102680107
retinoblastoma6 / 46356129
skin tumor60 / 124949480
soft tissue/muscle tissue tumor38 / 125191303
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue11 / 13106839
adrenal gland7 / 33197210
ascites14 / 40015349
bladder2 / 2975767
blood13 / 123478105
bone7 / 7165597
bone marrow3 / 4880161
brain58 / 110098952
cervix11 / 48171228
connective tissue20 / 149255133
ear0 / 162120 
embryonic tissue38 / 215722176
esophagus4 / 20209197
eye32 / 211054151
heart23 / 89626256
intestine25 / 234472106
kidney18 / 21177784
larynx0 / 241450 
liver40 / 207743192
lung63 / 336974186
lymph3 / 4427067
lymph node22 / 91610240
mammary gland8 / 15327152
mouth2 / 6705229
muscle6 / 10771555
nerve3 / 15768190
ovary18 / 102051176
pancreas32 / 214812148
parathyroid14 / 20539681
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta27 / 28082596
prostate19 / 189345100
salivary gland16 / 20155793
skin80 / 210574379
spleen6 / 53952111
stomach40 / 96619413
testis18 / 33044254
thymus5 / 8113161
thyroid3 / 4747363
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord12 / 13680877
uterus40 / 232878171
vascular12 / 51780231
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15081_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.41 ± 0.37
Basal Forebrain7.74 ± 0.18
Basal Part of Pons7.89 ± 0.47
Cerebellar Cortex7.61 ± 0.36
Cerebellar Nuclei8 ± 0.28
Claustrum7.3 ± 0.68
Epithalamus8.04 ± 0.37
Frontal Lobe7.93 ± 0.42
Globus Pallidus7.47 ± 0.49
Hypothalamus8.42 ± 0.39
Insula7.87 ± 0.37
Limbic Lobe7.39 ± 0.47
Mesencephalon7.77 ± 0.45
Myelencephalon7.67 ± 0.55
Occipital Lobe7.16 ± 0.48
Parietal Lobe7.78 ± 0.49
Pontine Tegmentum7.68 ± 0.45
Striatum7.11 ± 0.5
Subthalamus7.82 ± 0.55
Temporal Lobe7.9 ± 0.43
Thalamus7.57 ± 0.42
White Matter6.46 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpx1CBCerebellum5.18
6.33
Gpx1CTXCerebral cortex4.35
3.86
Gpx1HIPHippocampal region2.45
2.76
Gpx1HPFHippocampal formation1.89
1.96
Gpx1HYHypothalamus2.38
2.62
Gpx1LSXLateral septal complex1.84
1.6
Gpx1MBMidbrain2.03
2.56
Gpx1MYMedulla4.28
5.64
Gpx1OLFOlfactory bulb5.73
4.24
Gpx1PPons3.27
4.67
Gpx1PALPallidum2.95
3.06
Gpx1RHPRetrohippocampal region0.89
0.74
Gpx1sAMYStriatum-like amygdalar nuclei2.33
2.03
Gpx1STRStriatum6.3
4.6
Gpx1STRdStriatum dorsal region8.1
6.03
Gpx1STRvStriatum ventral region3.92
2.42
Gpx1THThalamus10.26
16.36
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018