AutismKB 2.0

Annotation Detail for GPX3


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Basic Information Top
Gene Symbol:GPX3 ( GPx-P,GSHPx-3,GSHPx-P )
Gene Full Name: glutathione peroxidase 3 (plasma)
Band: 5q33.1
Quick LinksEntrez ID:2878; OMIM: 138321; Uniprot ID:GPX3_HUMAN; ENSEMBL ID: ENSG00000211445; HGNC ID: 4555
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus64 / 564012113
neonate0 / 310970 
infant1 / 2362042
juvenile7 / 55556125
adult1059 / 1939121546
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma8 / 17475457
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor3 / 26384511
glioma14 / 106883130
head and neck tumor53 / 136302388
kidney tumor124 / 689591798
leukemia3 / 9584231
liver tumor22 / 96359228
lung tumor30 / 103127290
lymphoma0 / 717550 
non-neoplasia225 / 972502313
normal1266 / 3360307376
ovarian tumor31 / 76682404
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS22 / 125680175
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor19 / 125191151
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue12 / 13106915
adrenal gland3 / 3319790
ascites0 / 400150 
bladder8 / 29757268
blood4 / 12347832
bone4 / 7165555
bone marrow0 / 488010 
brain101 / 110098991
cervix1 / 4817120
connective tissue367 / 1492552458
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye381 / 2110541805
heart15 / 89626167
intestine19 / 23447281
kidney209 / 211777986
larynx38 / 241451573
liver45 / 207743216
lung86 / 336974255
lymph0 / 442700 
lymph node0 / 916100 
mammary gland24 / 153271156
mouth1 / 6705214
muscle8 / 10771574
nerve10 / 15768634
ovary32 / 102051313
pancreas54 / 214812251
parathyroid4 / 20539194
pharynx1 / 4132824
pituitary gland8 / 16585482
placenta192 / 280825683
prostate5 / 18934526
salivary gland12 / 20155595
skin7 / 21057433
spleen9 / 53952166
stomach9 / 9661993
testis7 / 33044221
thymus0 / 811310 
thyroid122 / 474732569
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus39 / 232878167
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P133474
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.59 ± 1
Basal Forebrain8.05 ± 0.41
Basal Part of Pons6.12 ± 0.48
Cerebellar Cortex6.66 ± 0.73
Cerebellar Nuclei7.5 ± 0.72
Claustrum5.07 ± 1.03
Epithalamus6.73 ± 0.55
Frontal Lobe6.85 ± 0.79
Globus Pallidus6.25 ± 0.86
Hypothalamus8.56 ± 0.29
Insula6.5 ± 0.62
Limbic Lobe6.07 ± 0.77
Mesencephalon7.04 ± 0.74
Myelencephalon6.5 ± 1.03
Occipital Lobe5.07 ± 0.84
Parietal Lobe6.72 ± 0.59
Pontine Tegmentum6.58 ± 0.96
Striatum7.23 ± 1.03
Subthalamus7.06 ± 0.49
Temporal Lobe6.07 ± 0.68
Thalamus5.75 ± 1.04
White Matter4.95 ± 0.96
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpx3CBCerebellum2.34
4.86
Gpx3CTXCerebral cortex2.36
1.61
Gpx3HIPHippocampal region0.56
0.45
Gpx3HPFHippocampal formation1.31
0.88
Gpx3HYHypothalamus55.04
41.94
Gpx3LSXLateral septal complex4.9
1.66
Gpx3MBMidbrain8.54
9.33
Gpx3MYMedulla8.84
9.61
Gpx3OLFOlfactory bulb4.48
2.71
Gpx3PPons13.4
14.16
Gpx3PALPallidum14.41
10.37
Gpx3RHPRetrohippocampal region2.22
1.31
Gpx3sAMYStriatum-like amygdalar nuclei32.88
21.41
Gpx3STRStriatum4.16
2.57
Gpx3STRdStriatum dorsal region0.47
0.31
Gpx3STRvStriatum ventral region0.56
0.32
Gpx3THThalamus4.71
3.76
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018