AutismKB 2.0

Annotation Detail for ANK3


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Basic Information Top
Gene Symbol:ANK3 ( ANKYRIN-G,FLJ45464 )
Gene Full Name: ankyrin 3, node of Ranvier (ankyrin G)
Band: 10q21.2
Quick LinksEntrez ID:288; OMIM: 600465; Uniprot ID:ANK3_HUMAN; ENSEMBL ID: ENSG00000151150; HGNC ID: 494
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus52 / 56401292
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult211 / 1939121108
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor22 / 26384583
glioma5 / 10688346
head and neck tumor7 / 13630251
kidney tumor7 / 68959101
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal286 / 336030785
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer44 / 102680428
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone0 / 716550 
bone marrow1 / 4880120
brain124 / 1100989112
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye14 / 21105466
heart9 / 89626100
intestine7 / 23447229
kidney20 / 21177794
larynx1 / 2414541
liver2 / 2077439
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland13 / 15327184
mouth3 / 6705244
muscle8 / 10771574
nerve2 / 15768126
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid11 / 20539535
pharynx3 / 4132872
pituitary gland3 / 16585180
placenta85 / 280825302
prostate52 / 189345274
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209442_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.85
Adipocyte19.05
AdrenalCortex31.75
Adrenalgland18.2
Amygdala67.95
Appendix29.45
AtrioventricularNode26.1
BDCA4+_DentriticCells10.8
Bonemarrow17.3
BronchialEpithelialCells22
CD105+_Endothelial14.3
CD14+_Monocytes12.05
CD19+_BCells(neg._sel.)17
CD33+_Myeloid13.35
CD34+9.6
CD4+_Tcells28.9
CD56+_NKCells9
CD71+_EarlyErythroid15.35
CD8+_Tcells14
CardiacMyocytes29.1
Caudatenucleus38.55
Cerebellum48.05
CerebellumPeduncles148.95
CiliaryGanglion19.35
CingulateCortex203.6
Colorectaladenocarcinoma13.8
DorsalRootGanglion24.65
FetalThyroid44.25
Fetalbrain92.9
Fetalliver25.75
Fetallung10.8
GlobusPallidus74.1
Heart43.9
Hypothalamus168
Kidney27.95
Leukemia_chronicMyelogenousK-56221.75
Leukemia_promyelocytic-HL-6012.65
Leukemialymphoblastic(MOLT-4)13.95
Liver34.35
Lung23.05
Lymphnode17.45
Lymphoma_burkitts(Daudi)20.5
Lymphoma_burkitts(Raji)28.95
MedullaOblongata217.65
OccipitalLobe110.25
OlfactoryBulb87.55
Ovary21.35
Pancreas12.1
PancreaticIslet18.3
ParietalLobe151.85
Pituitary38.2
Placenta44.4
Pons136.75
PrefrontalCortex179.1
Prostate27.35
Salivarygland21
SkeletalMuscle39.2
Skin21.6
SmoothMuscle17.3
Spinalcord41.65
SubthalamicNucleus94.1
SuperiorCervicalGanglion32
TemporalLobe96.3
Testis17.85
TestisGermCell17.8
TestisIntersitial18.7
TestisLeydigCell24.65
TestisSeminiferousTubule29.95
Thalamus28.55
Thymus11.3
Thyroid44.65
Tongue42
Tonsil23.25
Trachea26.8
TrigeminalGanglion38.55
Uterus21.95
UterusCorpus23.7
WholeBlood21.55
Wholebrain27.15
colon25.35
pineal_day55.96
pineal_night53.02
retina49.15
small_intestine21.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P301530
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.04 ± 0.2
Basal Forebrain11 ± 0.11
Basal Part of Pons11.73 ± 0.3
Cerebellar Cortex11.52 ± 0.2
Cerebellar Nuclei11.21 ± 0.19
Claustrum11.23 ± 0.29
Epithalamus10.22 ± 0.78
Frontal Lobe11.16 ± 0.35
Globus Pallidus10.93 ± 0.43
Hypothalamus10.87 ± 0.3
Insula11.02 ± 0.25
Limbic Lobe11.28 ± 0.42
Mesencephalon11.08 ± 0.37
Myelencephalon11.14 ± 0.44
Occipital Lobe11.53 ± 0.28
Parietal Lobe11.34 ± 0.36
Pontine Tegmentum11.17 ± 0.33
Striatum10.95 ± 0.42
Subthalamus11.6 ± 0.24
Temporal Lobe11.13 ± 0.31
Thalamus11.41 ± 0.31
White Matter12.25 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ank3CBCerebellum100
100
Ank3CTXCerebral cortex100
100
Ank3HIPHippocampal region100
100
Ank3HPFHippocampal formation100
100
Ank3HYHypothalamus100
100
Ank3LSXLateral septal complex100
100
Ank3MBMidbrain100
100
Ank3MYMedulla83.01
100
Ank3OLFOlfactory bulb100
100
Ank3PPons93.27
100
Ank3PALPallidum100
100
Ank3RHPRetrohippocampal region100
100
Ank3sAMYStriatum-like amygdalar nuclei100
100
Ank3STRStriatum100
100
Ank3STRdStriatum dorsal region100
100
Ank3STRvStriatum ventral region100
100
Ank3THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002979 18 1423 1440 GLPQTAVCNLNITLPAHK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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