AutismKB 2.0

Annotation Detail for GRIA2


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Basic Information Top
Gene Symbol:GRIA2 ( GLUR2,GLURB,GluA2,GluR-K2,HBGR2 )
Gene Full Name: glutamate receptor, ionotropic, AMPA 2
Band: 4q32.1
Quick LinksEntrez ID:2891; OMIM: 138247; Uniprot ID:GRIA2_HUMAN; ENSEMBL ID: ENSG00000120251; HGNC ID: 4572
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus63 / 564012111
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor11 / 26384541
glioma10 / 10688393
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal288 / 336030785
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain310 / 1100989281
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus19 / 23287881
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205358_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.05
Adipocyte4.05
AdrenalCortex4.7
Adrenalgland3.5
Amygdala806.05
Appendix4.55
AtrioventricularNode3.55
BDCA4+_DentriticCells4.55
Bonemarrow4.15
BronchialEpithelialCells4.05
CD105+_Endothelial4.15
CD14+_Monocytes4.45
CD19+_BCells(neg._sel.)4.35
CD33+_Myeloid5.25
CD34+5.2
CD4+_Tcells4.45
CD56+_NKCells4.8
CD71+_EarlyErythroid3.9
CD8+_Tcells3.9
CardiacMyocytes5.55
Caudatenucleus352.3
Cerebellum67.25
CerebellumPeduncles113.3
CiliaryGanglion3.2
CingulateCortex1027.9
Colorectaladenocarcinoma4.1
DorsalRootGanglion4.4
FetalThyroid4.1
Fetalbrain1412.15
Fetalliver3.6
Fetallung3.3
GlobusPallidus691.55
Heart5.45
Hypothalamus314.65
Kidney3.4
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.25
Liver5.55
Lung4.5
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.3
Lymphoma_burkitts(Raji)5.9
MedullaOblongata795.2
OccipitalLobe1123.95
OlfactoryBulb42.1
Ovary2.8
Pancreas3.4
PancreaticIslet4.45
ParietalLobe789.4
Pituitary247.95
Placenta4.2
Pons636.05
PrefrontalCortex2940.65
Prostate4.75
Salivarygland3.4
SkeletalMuscle4.85
Skin3.2
SmoothMuscle4.65
Spinalcord11.55
SubthalamicNucleus1060.85
SuperiorCervicalGanglion9.7
TemporalLobe724.5
Testis3.55
TestisGermCell3.45
TestisIntersitial3.55
TestisLeydigCell4.15
TestisSeminiferousTubule3.55
Thalamus164.6
Thymus3.2
Thyroid5.1
Tongue4.1
Tonsil4.05
Trachea3.45
TrigeminalGanglion4.35
Uterus10.4
UterusCorpus3.75
WholeBlood4.6
Wholebrain355.1
colon4.15
pineal_day62.98
pineal_night44.14
retina43.025
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_301_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.45 ± 0.46
Basal Forebrain5.72 ± 0.53
Basal Part of Pons5.29 ± 0.4
Cerebellar Cortex5.31 ± 0.34
Cerebellar Nuclei5.17 ± 0.47
Claustrum5.89 ± 0.52
Epithalamus4.69 ± 0.58
Frontal Lobe5.88 ± 0.62
Globus Pallidus4.78 ± 0.78
Hypothalamus5.47 ± 0.59
Insula5.95 ± 0.56
Limbic Lobe6.29 ± 0.61
Mesencephalon5.6 ± 0.52
Myelencephalon5.66 ± 0.62
Occipital Lobe5.81 ± 0.63
Parietal Lobe5.8 ± 0.62
Pontine Tegmentum5.8 ± 0.55
Striatum5.8 ± 0.83
Subthalamus5.74 ± 0.32
Temporal Lobe5.86 ± 0.64
Thalamus5.19 ± 0.6
White Matter4.64 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gria2CBCerebellum100
100
Gria2CTXCerebral cortex100
100
Gria2HIPHippocampal region100
100
Gria2HPFHippocampal formation100
100
Gria2HYHypothalamus100
100
Gria2LSXLateral septal complex100
100
Gria2MBMidbrain100
100
Gria2MYMedulla100
100
Gria2OLFOlfactory bulb100
100
Gria2PPons100
100
Gria2PALPallidum100
100
Gria2RHPRetrohippocampal region100
100
Gria2sAMYStriatum-like amygdalar nuclei100
100
Gria2STRStriatum100
100
Gria2STRdStriatum dorsal region100
100
Gria2STRvStriatum ventral region100
100
Gria2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GRIA2_HUMAN_24 12 24 35 SNSIQIGGLFPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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