AutismKB 2.0

Annotation Detail for GRIA3


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Basic Information Top
Gene Symbol:GRIA3 ( GLUR-C,GLUR-K3,GLUR3,GLURC,GluA3,MRX94 )
Gene Full Name: glutamate receptor, ionotrophic, AMPA 3
Band: Xq25
Quick LinksEntrez ID:2892; OMIM: 305915; Uniprot ID:GRIA3_HUMAN; ENSEMBL ID: ENSG00000125675; HGNC ID: 4573
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus32 / 56401256
neonate3 / 3109796
infant0 / 236200 
juvenile0 / 555560 
adult27 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal123 / 336030736
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain88 / 110098979
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung12 / 33697435
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206730_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.85
Adipocyte5.75
AdrenalCortex6.55
Adrenalgland5
Amygdala7.95
Appendix6
AtrioventricularNode6.15
BDCA4+_DentriticCells5.95
Bonemarrow5.9
BronchialEpithelialCells5.7
CD105+_Endothelial5.95
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7.55
CD34+7.15
CD4+_Tcells6.1
CD56+_NKCells6.65
CD71+_EarlyErythroid5.6
CD8+_Tcells5.4
CardiacMyocytes9.05
Caudatenucleus5.4
Cerebellum4.85
CerebellumPeduncles6.75
CiliaryGanglion4.45
CingulateCortex9.6
Colorectaladenocarcinoma5.9
DorsalRootGanglion4.95
FetalThyroid5.8
Fetalbrain7.7
Fetalliver5.15
Fetallung4.75
GlobusPallidus5.1
Heart8.45
Hypothalamus6.5
Kidney5.1
Leukemia_chronicMyelogenousK-5625.35
Leukemia_promyelocytic-HL-605.25
Leukemialymphoblastic(MOLT-4)4.7
Liver7.85
Lung6.45
Lymphnode5
Lymphoma_burkitts(Daudi)7.85
Lymphoma_burkitts(Raji)8.45
MedullaOblongata5.75
OccipitalLobe8.8
OlfactoryBulb4.7
Ovary4
Pancreas4.75
PancreaticIslet6.4
ParietalLobe7.85
Pituitary6.95
Placenta6.05
Pons5.9
PrefrontalCortex8.75
Prostate6.8
Salivarygland4.75
SkeletalMuscle7.85
Skin4.8
SmoothMuscle6.75
Spinalcord6.35
SubthalamicNucleus5.7
SuperiorCervicalGanglion7.5
TemporalLobe5.45
Testis5.1
TestisGermCell4.75
TestisIntersitial5
TestisLeydigCell6.05
TestisSeminiferousTubule5.1
Thalamus6.05
Thymus4.55
Thyroid7.15
Tongue6.2
Tonsil5.8
Trachea4.9
TrigeminalGanglion6.35
Uterus4.8
UterusCorpus5.35
WholeBlood6.5
Wholebrain5.05
colon5.95
pineal_day7.94
pineal_night7.3
retina7.075
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P177897
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.04 ± 0.47
Basal Forebrain8.06 ± 0.44
Basal Part of Pons8.29 ± 0.31
Cerebellar Cortex7.7 ± 0.36
Cerebellar Nuclei8.36 ± 0.52
Claustrum7.58 ± 0.7
Epithalamus7.12 ± 0.85
Frontal Lobe8.71 ± 0.52
Globus Pallidus7.37 ± 1.02
Hypothalamus7.83 ± 0.76
Insula8.83 ± 0.67
Limbic Lobe9.1 ± 0.58
Mesencephalon8.3 ± 0.67
Myelencephalon8.28 ± 0.68
Occipital Lobe8.39 ± 0.57
Parietal Lobe8.61 ± 0.63
Pontine Tegmentum8.49 ± 0.67
Striatum8.47 ± 0.95
Subthalamus8.35 ± 0.48
Temporal Lobe8.58 ± 0.45
Thalamus7.84 ± 0.47
White Matter6.98 ± 0.9
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gria3CBCerebellum100
100
Gria3CTXCerebral cortex100
100
Gria3HIPHippocampal region100
100
Gria3HPFHippocampal formation100
100
Gria3HYHypothalamus94.58
92.96
Gria3LSXLateral septal complex100
100
Gria3MBMidbrain99.6
100
Gria3MYMedulla93.38
100
Gria3OLFOlfactory bulb100
100
Gria3PPons86.68
100
Gria3PALPallidum94.31
100
Gria3RHPRetrohippocampal region100
100
Gria3sAMYStriatum-like amygdalar nuclei100
100
Gria3STRStriatum100
100
Gria3STRdStriatum dorsal region100
100
Gria3STRvStriatum ventral region100
100
Gria3THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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