AutismKB 2.0

Annotation Detail for CCDC22


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Basic Information Top
Gene Symbol:CCDC22 ( CXorf37 )
Gene Full Name: coiled-coil domain containing 22
Band: Xp11.23
Quick LinksEntrez ID:28952; OMIM: NA; Uniprot ID:CCD22_HUMAN; ENSEMBL ID: ENSG00000101997; HGNC ID: 28909
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus4 / 5640127
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma7 / 10688365
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma12 / 71755167
non-neoplasia0 / 972500 
normal53 / 336030715
ovarian tumor2 / 7668226
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood10 / 12347880
bone1 / 7165513
bone marrow3 / 4880161
brain18 / 110098916
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye3 / 21105414
heart0 / 896260 
intestine8 / 23447234
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung12 / 33697435
lymph5 / 44270112
lymph node1 / 9161010
mammary gland3 / 15327119
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen2 / 5395237
stomach0 / 966190 
testis1 / 3304423
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214037_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts28.35
Adipocyte19.2
AdrenalCortex26.7
Adrenalgland19.9
Amygdala9.1
Appendix22.8
AtrioventricularNode35.8
BDCA4+_DentriticCells22.8
Bonemarrow25.25
BronchialEpithelialCells15.2
CD105+_Endothelial23.7
CD14+_Monocytes68.95
CD19+_BCells(neg._sel.)25.75
CD33+_Myeloid88.55
CD34+30.75
CD4+_Tcells24.35
CD56+_NKCells38.35
CD71+_EarlyErythroid19.55
CD8+_Tcells31.3
CardiacMyocytes28.9
Caudatenucleus19.5
Cerebellum17.25
CerebellumPeduncles53.05
CiliaryGanglion20.95
CingulateCortex29.5
Colorectaladenocarcinoma20.15
DorsalRootGanglion16.85
FetalThyroid32.45
Fetalbrain18.9
Fetalliver17
Fetallung13.2
GlobusPallidus33.65
Heart29.05
Hypothalamus21.15
Kidney21.55
Leukemia_chronicMyelogenousK-56219.55
Leukemia_promyelocytic-HL-6020.05
Leukemialymphoblastic(MOLT-4)20.6
Liver28.35
Lung27.3
Lymphnode20.8
Lymphoma_burkitts(Daudi)26.25
Lymphoma_burkitts(Raji)29.55
MedullaOblongata19.95
OccipitalLobe19.25
OlfactoryBulb16.45
Ovary14.55
Pancreas18.5
PancreaticIslet21.95
ParietalLobe34.1
Pituitary25.35
Placenta15.25
Pons25.25
PrefrontalCortex22.35
Prostate24.55
Salivarygland19.25
SkeletalMuscle54.05
Skin18.25
SmoothMuscle23.6
Spinalcord22.7
SubthalamicNucleus19.15
SuperiorCervicalGanglion32.7
TemporalLobe19.3
Testis14.7
TestisGermCell17.3
TestisIntersitial16.45
TestisLeydigCell21.55
TestisSeminiferousTubule18.45
Thalamus41.4
Thymus10
Thyroid14
Tongue28.3
Tonsil25.7
Trachea14.65
TrigeminalGanglion87.6
Uterus11.15
UterusCorpus20.45
WholeBlood16.6
Wholebrain12.15
colon19.95
pineal_day35.74
pineal_night34.98
retina21.925
small_intestine14.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13336_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.53 ± 0.32
Basal Forebrain5.23 ± 0.48
Basal Part of Pons5.27 ± 0.43
Cerebellar Cortex5.63 ± 0.45
Cerebellar Nuclei5.24 ± 0.44
Claustrum5.17 ± 0.86
Epithalamus5.05 ± 0.53
Frontal Lobe5.34 ± 0.49
Globus Pallidus5.26 ± 0.23
Hypothalamus5.13 ± 0.52
Insula5.19 ± 0.44
Limbic Lobe5.22 ± 0.49
Mesencephalon5.2 ± 0.42
Myelencephalon5.26 ± 0.55
Occipital Lobe5.01 ± 0.5
Parietal Lobe5.2 ± 0.48
Pontine Tegmentum5.18 ± 0.56
Striatum4.88 ± 0.47
Subthalamus4.7 ± 0.43
Temporal Lobe5.36 ± 0.44
Thalamus5.11 ± 0.5
White Matter6.14 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ccdc22CBCerebellum24.18
26.63
Ccdc22CTXCerebral cortex82.37
63.39
Ccdc22HIPHippocampal region48.93
54.55
Ccdc22HPFHippocampal formation62.67
62.83
Ccdc22HYHypothalamus33.61
27.34
Ccdc22LSXLateral septal complex5.93
3.9
Ccdc22MBMidbrain35.82
30.87
Ccdc22MYMedulla39.15
45.68
Ccdc22OLFOlfactory bulb58.53
52.17
Ccdc22PPons43.15
44.46
Ccdc22PALPallidum32.77
29.67
Ccdc22RHPRetrohippocampal region91.61
79.4
Ccdc22sAMYStriatum-like amygdalar nuclei59.02
46.17
Ccdc22STRStriatum24.5
18.93
Ccdc22STRdStriatum dorsal region16.36
12.18
Ccdc22STRvStriatum ventral region41
32.41
Ccdc22THThalamus60.24
50.89
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CCD22_HUMAN_402 11 402 412 LQLVVENSAQR PRIDE
PAp00008127 18 203 220 VASLLEHHALQLCQQTGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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