AutismKB 2.0

Annotation Detail for DEXI


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Basic Information Top
Gene Symbol:DEXI ( MYLE )
Gene Full Name: Dexi homolog (mouse)
Band: 16p13.13
Quick LinksEntrez ID:28955; OMIM: NA; Uniprot ID:DEXI_HUMAN; ENSEMBL ID: ENSG00000182108; HGNC ID: 13267
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus16 / 56401228
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor5 / 26384518
glioma11 / 106883102
head and neck tumor5 / 13630236
kidney tumor11 / 68959159
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal100 / 336030729
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain32 / 110098929
cervix3 / 4817162
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine6 / 23447225
kidney13 / 21177761
larynx0 / 241450 
liver6 / 20774328
lung12 / 33697435
lymph0 / 442700 
lymph node4 / 9161043
mammary gland2 / 15327113
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary5 / 10205148
pancreas11 / 21481251
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta14 / 28082549
prostate3 / 18934515
salivary gland4 / 20155198
skin8 / 21057437
spleen6 / 53952111
stomach4 / 9661941
testis3 / 3304429
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203733_at
Cell line Expression level Expression bar
721_B_lymphoblasts23.95
Adipocyte72.15
AdrenalCortex69.95
Adrenalgland69.65
Amygdala24.05
Appendix10.95
AtrioventricularNode8.5
BDCA4+_DentriticCells17.95
Bonemarrow10.75
BronchialEpithelialCells51.55
CD105+_Endothelial88.1
CD14+_Monocytes12.2
CD19+_BCells(neg._sel.)13.5
CD33+_Myeloid21
CD34+32.15
CD4+_Tcells30.2
CD56+_NKCells65.7
CD71+_EarlyErythroid22.35
CD8+_Tcells18.7
CardiacMyocytes13.6
Caudatenucleus14.65
Cerebellum23.35
CerebellumPeduncles21.15
CiliaryGanglion12.25
CingulateCortex46.15
Colorectaladenocarcinoma12.6
DorsalRootGanglion11.55
FetalThyroid21.1
Fetalbrain8.35
Fetalliver10.3
Fetallung11.95
GlobusPallidus21.75
Heart171.55
Hypothalamus31.6
Kidney17.8
Leukemia_chronicMyelogenousK-56210.05
Leukemia_promyelocytic-HL-609.7
Leukemialymphoblastic(MOLT-4)12.5
Liver221.95
Lung106.15
Lymphnode13.5
Lymphoma_burkitts(Daudi)5.75
Lymphoma_burkitts(Raji)11.05
MedullaOblongata25.75
OccipitalLobe14.25
OlfactoryBulb21.9
Ovary7.4
Pancreas11.65
PancreaticIslet16.85
ParietalLobe12.2
Pituitary26.35
Placenta33.75
Pons15.5
PrefrontalCortex96.25
Prostate23.85
Salivarygland10.9
SkeletalMuscle20.25
Skin12.05
SmoothMuscle26.65
Spinalcord20.05
SubthalamicNucleus30.75
SuperiorCervicalGanglion12.4
TemporalLobe36
Testis13.15
TestisGermCell11.05
TestisIntersitial11.8
TestisLeydigCell6.8
TestisSeminiferousTubule12.7
Thalamus65.7
Thymus14.85
Thyroid45.7
Tongue17.25
Tonsil12.85
Trachea13.1
TrigeminalGanglion16.85
Uterus14.65
UterusCorpus14.75
WholeBlood14.45
Wholebrain137.9
colon11.3
pineal_day96.04
pineal_night136.78
retina63.925
small_intestine12.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P54441
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.24 ± 0.24
Basal Forebrain8.77 ± 0.23
Basal Part of Pons9 ± 0.16
Cerebellar Cortex8.52 ± 0.29
Cerebellar Nuclei9.29 ± 0.38
Claustrum8.13 ± 0.41
Epithalamus8.44 ± 0.17
Frontal Lobe8.77 ± 0.37
Globus Pallidus9.03 ± 0.36
Hypothalamus8.48 ± 0.17
Insula8.59 ± 0.24
Limbic Lobe8.24 ± 0.35
Mesencephalon8.58 ± 0.34
Myelencephalon8.64 ± 0.37
Occipital Lobe8.44 ± 0.29
Parietal Lobe8.8 ± 0.39
Pontine Tegmentum8.58 ± 0.47
Striatum8.62 ± 0.25
Subthalamus9.14 ± 0.15
Temporal Lobe8.6 ± 0.28
Thalamus8.87 ± 0.36
White Matter7.71 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DexiCBCerebellum17.63
23.88
DexiCTXCerebral cortex22.19
18.42
DexiHIPHippocampal region15.05
15.81
DexiHPFHippocampal formation17.13
16.21
DexiHYHypothalamus5.49
4.97
DexiLSXLateral septal complex1.66
1.17
DexiMBMidbrain16.61
18.94
DexiMYMedulla32.12
44.85
DexiOLFOlfactory bulb17.7
15.09
DexiPPons25.61
33.58
DexiPALPallidum10.32
10.93
DexiRHPRetrohippocampal region21.45
17.5
DexisAMYStriatum-like amygdalar nuclei4.19
3.36
DexiSTRStriatum4.88
3.8
DexiSTRdStriatum dorsal region4.25
3.38
DexiSTRvStriatum ventral region9.13
6.5
DexiTHThalamus20.7
18.73
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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