Annotation Detail for GIT1
Basic Information Top
| Gene Symbol: | GIT1 ( - ) |
|---|---|
| Gene Full Name: | G protein-coupled receptor kinase interacting ArfGAP 1 |
| Band: | 17q11.2 |
| Quick Links | Entrez ID:28964; OMIM: 608434; Uniprot ID:GIT1_HUMAN; ENSEMBL ID: ENSG00000108262; HGNC ID: 4272 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.514051
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 5 / 70761 | 70 |  |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 39 / 564012 | 69 | |
| neonate | 1 / 31097 | 32 | |
| infant | 2 / 23620 | 84 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 129 / 1939121 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 8 / 82823 | 96 | |
| colorectal tumor | 8 / 114246 | 70 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 13 / 263845 | 49 | |
| glioma | 14 / 106883 | 130 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 7 / 95842 | 73 | |
| liver tumor | 7 / 96359 | 72 | |
| lung tumor | 21 / 103127 | 203 |  |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 6 / 97250 | 61 | |
| normal | 227 / 3360307 | 67 | |
| ovarian tumor | 11 / 76682 | 143 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 16 / 125680 | 127 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 4 / 46356 | 86 | |
| skin tumor | 11 / 124949 | 88 | |
| soft tissue/muscle tissue tumor | 23 / 125191 | 183 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 4 / 40015 | 99 | |
| bladder | 1 / 29757 | 33 | |
| blood | 8 / 123478 | 64 | |
| bone | 8 / 71655 | 111 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 118 / 1100989 | 107 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 1 / 149255 | 6 |  |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 10 / 215722 | 46 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 19 / 211054 | 90 | |
| heart | 6 / 89626 | 66 | |
| intestine | 13 / 234472 | 55 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 0 / 24145 | 0 | |
| liver | 7 / 207743 | 33 | |
| lung | 37 / 336974 | 109 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 9 / 91610 | 98 | |
| mammary gland | 12 / 153271 | 78 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 21 / 107715 | 194 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 12 / 102051 | 117 | |
| pancreas | 18 / 214812 | 83 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 6 / 280825 | 21 | |
| prostate | 6 / 189345 | 31 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 14 / 210574 | 66 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 0 / 96619 | 0 | |
| testis | 23 / 330442 | 69 | |
| thymus | 9 / 81131 | 110 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 8 / 232878 | 34 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218030_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 142.95 | |
| Adipocyte | 93.35 | |
| AdrenalCortex | 90.9 | |
| Adrenalgland | 102.6 | |
| Amygdala | 216 | |
| Appendix | 39.45 | |
| AtrioventricularNode | 61.8 | |
| BDCA4+_DentriticCells | 142.45 | |
| Bonemarrow | 188.5 | |
| BronchialEpithelialCells | 59 | |
| CD105+_Endothelial | 177.7 | |
| CD14+_Monocytes | 104.8 | |
| CD19+_BCells(neg._sel.) | 105.05 | |
| CD33+_Myeloid | 233.9 | |
| CD34+ | 176 | |
| CD4+_Tcells | 197.55 | |
| CD56+_NKCells | 157.7 | |
| CD71+_EarlyErythroid | 300 | |
| CD8+_Tcells | 132.35 | |
| CardiacMyocytes | 132.35 | |
| Caudatenucleus | 160.85 | |
| Cerebellum | 108.2 | |
| CerebellumPeduncles | 126.85 | |
| CiliaryGanglion | 48 | |
| CingulateCortex | 178.65 | |
| Colorectaladenocarcinoma | 160.65 | |
| DorsalRootGanglion | 56.95 | |
| FetalThyroid | 140.35 | |
| Fetalbrain | 149.65 | |
| Fetalliver | 105.85 | |
| Fetallung | 72.65 | |
| GlobusPallidus | 171.25 | |
| Heart | 246.7 | |
| Hypothalamus | 88.5 | |
| Kidney | 96.75 | |
| Leukemia_chronicMyelogenousK-562 | 88.1 | |
| Leukemia_promyelocytic-HL-60 | 73.1 | |
| Leukemialymphoblastic(MOLT-4) | 112.95 | |
| Liver | 86.2 | |
| Lung | 108.3 | |
| Lymphnode | 81.2 | |
| Lymphoma_burkitts(Daudi) | 108.05 | |
| Lymphoma_burkitts(Raji) | 193.35 | |
| MedullaOblongata | 113.35 | |
| OccipitalLobe | 152.75 | |
| OlfactoryBulb | 92.25 | |
| Ovary | 55.85 | |
| Pancreas | 58.7 | |
| PancreaticIslet | 67.85 | |
| ParietalLobe | 126.85 | |
| Pituitary | 123.6 | |
| Placenta | 90.45 | |
| Pons | 166.15 | |
| PrefrontalCortex | 245.7 | |
| Prostate | 115.6 | |
| Salivarygland | 56.8 | |
| SkeletalMuscle | 53.9 | |
| Skin | 88 | |
| SmoothMuscle | 78.7 | |
| Spinalcord | 76.45 | |
| SubthalamicNucleus | 193.5 | |
| SuperiorCervicalGanglion | 35.55 | |
| TemporalLobe | 217.25 | |
| Testis | 226.35 | |
| TestisGermCell | 104.95 | |
| TestisIntersitial | 192.9 | |
| TestisLeydigCell | 121.5 | |
| TestisSeminiferousTubule | 165.8 | |
| Thalamus | 178.85 | |
| Thymus | 83.4 | |
| Thyroid | 110.9 | |
| Tongue | 58.4 | |
| Tonsil | 82.8 | |
| Trachea | 104.55 | |
| TrigeminalGanglion | 127.1 | |
| Uterus | 45.75 | |
| UterusCorpus | 43.45 | |
| WholeBlood | 68.95 | |
| Wholebrain | 123.6 | |
| colon | 60.8 | |
| pineal_day | 203.74 | |
| pineal_night | 188.92 | |
| retina | 203.55 | |
| small_intestine | 55.6 | |
- Probe name: A_23_P100912
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.05 ± 0.52 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.62 ± 0.09 | |
| Basal Part of Pons | 4.52 ± 0.39 | |
| Cerebellar Cortex | 4.23 ± 0.3 | |
| Cerebellar Nuclei | 4.15 ± 0.44 | |
| Claustrum | 4.7 ± 0.6 | |
| Epithalamus | 4 ± 0.61 | |
| Frontal Lobe | 4.7 ± 0.49 | |
| Globus Pallidus | 3.77 ± 0.63 | |
| Hypothalamus | 3.96 ± 0.56 | |
| Insula | 4.68 ± 0.37 | |
| Limbic Lobe | 5.08 ± 0.44 | |
| Mesencephalon | 4.59 ± 0.61 | |
| Myelencephalon | 4.62 ± 0.54 | |
| Occipital Lobe | 4.46 ± 0.48 | |
| Parietal Lobe | 4.72 ± 0.6 | |
| Pontine Tegmentum | 4.66 ± 0.55 | |
| Striatum | 5.32 ± 0.41 | |
| Subthalamus | 3.94 ± 0.53 | |
| Temporal Lobe | 4.79 ± 0.47 | |
| Thalamus | 4.52 ± 0.43 | |
| White Matter | 3.53 ± 0.72 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Git1 | CB | Cerebellum | 35.86 | |
| 45.34 | | |||
| Git1 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Git1 | HIP | Hippocampal region | 85.59 | |
| 100 | | |||
| Git1 | HPF | Hippocampal formation | 95.44 | |
| 100 | | |||
| Git1 | HY | Hypothalamus | 48.45 | |
| 40.73 | | |||
| Git1 | LSX | Lateral septal complex | 65.4 | |
| 51.72 | | |||
| Git1 | MB | Midbrain | 54.77 | |
| 53.68 | | |||
| Git1 | MY | Medulla | 66.55 | |
| 78.82 | | |||
| Git1 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Git1 | P | Pons | 58.43 | |
| 66.05 | | |||
| Git1 | PAL | Pallidum | 64.54 | |
| 63.25 | | |||
| Git1 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Git1 | sAMY | Striatum-like amygdalar nuclei | 91.47 | |
| 79.28 | | |||
| Git1 | STR | Striatum | 98.43 | |
| 81.23 | | |||
| Git1 | STRd | Striatum dorsal region | 100 | |
| 87.89 | | |||
| Git1 | STRv | Striatum ventral region | 96.64 | |
| 74.58 | | |||
| Git1 | TH | Thalamus | 70.61 | |
| 63.82 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| GIT1_HUMAN_209 | 10 | 209 | 218 | QAGHHELAER | PRIDE |
| PAp00026170 | 25 | 558 | 582 | KGVSASAVPFTPSSPLLSCSQEGSR | Peptide Atlas |