AutismKB 2.0

Annotation Detail for TMEM14A


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Basic Information Top
Gene Symbol:TMEM14A ( C6orf73 )
Gene Full Name: transmembrane protein 14A
Band: 6p12.2
Quick LinksEntrez ID:28978; OMIM: NA; Uniprot ID:TM14A_HUMAN; ENSEMBL ID: ENSG00000096092; HGNC ID: 21076
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma7 / 17475400
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal123 / 336030736
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder7 / 29757235
blood1 / 1234788
bone1 / 7165513
bone marrow5 / 48801102
brain81 / 110098973
cervix0 / 481710 
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye8 / 21105437
heart3 / 8962633
intestine2 / 2344728
kidney9 / 21177742
larynx0 / 241450 
liver7 / 20774333
lung11 / 33697432
lymph0 / 442700 
lymph node4 / 9161043
mammary gland4 / 15327126
mouth1 / 6705214
muscle6 / 10771555
nerve0 / 157680 
ovary5 / 10205148
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin11 / 21057452
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218477_at
Cell line Expression level Expression bar
721_B_lymphoblasts101.75
Adipocyte43
AdrenalCortex12.05
Adrenalgland131.95
Amygdala404.7
Appendix11.4
AtrioventricularNode12.05
BDCA4+_DentriticCells23.4
Bonemarrow14.25
BronchialEpithelialCells95.45
CD105+_Endothelial126.6
CD14+_Monocytes5.8
CD19+_BCells(neg._sel.)31.25
CD33+_Myeloid9.05
CD34+87
CD4+_Tcells15.2
CD56+_NKCells31.4
CD71+_EarlyErythroid7.85
CD8+_Tcells14.05
CardiacMyocytes35.65
Caudatenucleus107.95
Cerebellum86.75
CerebellumPeduncles171.1
CiliaryGanglion12.75
CingulateCortex145.35
Colorectaladenocarcinoma56.3
DorsalRootGanglion26.6
FetalThyroid28.15
Fetalbrain329.9
Fetalliver58.1
Fetallung17
GlobusPallidus91.45
Heart13.5
Hypothalamus351.8
Kidney60.75
Leukemia_chronicMyelogenousK-5627.45
Leukemia_promyelocytic-HL-60122.95
Leukemialymphoblastic(MOLT-4)61.75
Liver46.05
Lung71.6
Lymphnode18.75
Lymphoma_burkitts(Daudi)28.2
Lymphoma_burkitts(Raji)102.3
MedullaOblongata143.3
OccipitalLobe188.7
OlfactoryBulb31.8
Ovary7.1
Pancreas25.9
PancreaticIslet58.6
ParietalLobe108.45
Pituitary103.4
Placenta34.65
Pons72
PrefrontalCortex246
Prostate136.45
Salivarygland12.8
SkeletalMuscle9.8
Skin6.6
SmoothMuscle70.85
Spinalcord157.15
SubthalamicNucleus147.65
SuperiorCervicalGanglion12.15
TemporalLobe153.35
Testis33.8
TestisGermCell23.05
TestisIntersitial8.9
TestisLeydigCell10.7
TestisSeminiferousTubule13.2
Thalamus193.45
Thymus36.35
Thyroid119.65
Tongue27.95
Tonsil20.85
Trachea53.3
TrigeminalGanglion11.45
Uterus82.65
UterusCorpus7.55
WholeBlood11.65
Wholebrain601.85
colon116.1
pineal_day195.06
pineal_night186.52
retina306.525
small_intestine239.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1514_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.77 ± 0.15
Basal Forebrain9.65 ± 0.25
Basal Part of Pons10.06 ± 0.14
Cerebellar Cortex9.71 ± 0.22
Cerebellar Nuclei10.01 ± 0.29
Claustrum10.01 ± 0.3
Epithalamus9.42 ± 0.21
Frontal Lobe9.98 ± 0.32
Globus Pallidus9.63 ± 0.39
Hypothalamus10.32 ± 0.3
Insula9.87 ± 0.19
Limbic Lobe9.7 ± 0.37
Mesencephalon9.79 ± 0.37
Myelencephalon9.79 ± 0.41
Occipital Lobe9.78 ± 0.38
Parietal Lobe9.9 ± 0.36
Pontine Tegmentum9.9 ± 0.37
Striatum9.23 ± 0.42
Subthalamus10.08 ± 0.34
Temporal Lobe9.89 ± 0.27
Thalamus9.91 ± 0.3
White Matter9.2 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem14aCBCerebellum20.33
35.36
Tmem14aCTXCerebral cortex85.32
79.53
Tmem14aHIPHippocampal region34.21
55.6
Tmem14aHPFHippocampal formation40.37
49.83
Tmem14aHYHypothalamus27.29
24.62
Tmem14aLSXLateral septal complex23.79
19.07
Tmem14aMBMidbrain29.09
29.83
Tmem14aMYMedulla36.64
47.9
Tmem14aOLFOlfactory bulb44.74
41.08
Tmem14aPPons21.89
27.61
Tmem14aPALPallidum33.72
31.26
Tmem14aRHPRetrohippocampal region49.7
42.68
Tmem14asAMYStriatum-like amygdalar nuclei12.2
9.24
Tmem14aSTRStriatum36.62
28.65
Tmem14aSTRdStriatum dorsal region42.25
33.21
Tmem14aSTRvStriatum ventral region38.63
28.73
Tmem14aTHThalamus35.18
33.35
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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