AutismKB 2.0

Annotation Detail for DBNL


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Basic Information Top
Gene Symbol:DBNL ( ABP1,HIP-55,SH3P7 )
Gene Full Name: drebrin-like
Band: 7p13
Quick LinksEntrez ID:28988; OMIM: 610106; Uniprot ID:DBNL_HUMAN; ENSEMBL ID: ENSG00000136279; HGNC ID: 2696
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst7 / 62319112
fetus37 / 56401265
neonate26 / 31097836
infant10 / 23620423
juvenile27 / 55556485
adult310 / 1939121159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor17 / 94178180
cervical tumor5 / 34366145
chondrosarcoma4 / 8282348
colorectal tumor16 / 114246140
esophageal tumor5 / 17290289
gastrointestinal tumor17 / 119369142
germ cell tumor77 / 263845291
glioma70 / 106883654
head and neck tumor25 / 136302183
kidney tumor19 / 68959275
leukemia21 / 95842219
liver tumor14 / 96359145
lung tumor38 / 103127368
lymphoma40 / 71755557
non-neoplasia39 / 97250401
normal643 / 3360307191
ovarian tumor11 / 76682143
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS59 / 125680469
prostate cancer2 / 10268019
retinoblastoma4 / 4635686
skin tumor29 / 124949232
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland8 / 33197240
ascites9 / 40015224
bladder8 / 29757268
blood58 / 123478469
bone5 / 7165569
bone marrow9 / 48801184
brain324 / 1100989294
cervix14 / 48171290
connective tissue38 / 149255254
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus6 / 20209296
eye22 / 211054104
heart14 / 89626156
intestine53 / 234472226
kidney44 / 211777207
larynx0 / 241450 
liver18 / 20774386
lung64 / 336974189
lymph30 / 44270677
lymph node11 / 91610120
mammary gland24 / 153271156
mouth5 / 6705274
muscle7 / 10771564
nerve0 / 157680 
ovary18 / 102051176
pancreas20 / 21481293
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta37 / 280825131
prostate18 / 18934595
salivary gland18 / 20155893
skin52 / 210574246
spleen57 / 539521056
stomach15 / 96619155
testis26 / 33044278
thymus57 / 81131702
thyroid8 / 47473168
tonsil20 / 169991176
trachea15 / 52413286
umbilical cord4 / 13680292
uterus36 / 232878154
vascular23 / 51780444
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P168692
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.15 ± 0.73
Basal Forebrain6.02 ± 0.35
Basal Part of Pons6.08 ± 0.38
Cerebellar Cortex5.83 ± 0.35
Cerebellar Nuclei5.92 ± 0.38
Claustrum6.52 ± 0.62
Epithalamus5.69 ± 0.3
Frontal Lobe6.05 ± 0.36
Globus Pallidus6.22 ± 0.48
Hypothalamus5.86 ± 0.34
Insula6.01 ± 0.24
Limbic Lobe6.32 ± 0.39
Mesencephalon5.97 ± 0.43
Myelencephalon6.08 ± 0.42
Occipital Lobe6.06 ± 0.41
Parietal Lobe6.03 ± 0.39
Pontine Tegmentum6.02 ± 0.42
Striatum5.97 ± 0.47
Subthalamus5.61 ± 0.16
Temporal Lobe6.15 ± 0.37
Thalamus5.95 ± 0.42
White Matter6.56 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
DbnlCBCerebellum32.09
54.97
DbnlCTXCerebral cortex100
100
DbnlHIPHippocampal region84.61
100
DbnlHPFHippocampal formation92.35
100
DbnlHYHypothalamus95.9
94.22
DbnlLSXLateral septal complex82.77
76.78
DbnlMBMidbrain79
88.56
DbnlMYMedulla59.11
89.22
DbnlOLFOlfactory bulb95.56
98.98
DbnlPPons70.27
93.34
DbnlPALPallidum86.01
98.51
DbnlRHPRetrohippocampal region100
100
DbnlsAMYStriatum-like amygdalar nuclei100
100
DbnlSTRStriatum91.22
80.16
DbnlSTRdStriatum dorsal region86.42
75.19
DbnlSTRvStriatum ventral region92.51
77.01
DbnlTHThalamus86.59
88.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DBNL_HUMAN_118 13 118 130 AEEDVEPECIMEK PRIDE
DBNL_HUMAN_148 16 148 163 FQDVGPQAPVGSVYQK PRIDE
DBNL_HUMAN_149 16 149 164 FQDVGPQAPVGSVYQK PRIDE
DBNL_HUMAN_235 11 235 245 TWEQQQEVVSR PRIDE
DBNL_HUMAN_289 11 289 299 QLTQPETHFGR PRIDE
DBNL_HUMAN_411 20 411 430 GYGPDGHFGMFPANYVELIE PRIDE
DBNL_HUMAN_78 15 78 92 FVLINWTGEGVNDVR PRIDE
PAp00000286 13 119 131 AEEDVEPECIMEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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