AutismKB 2.0

Annotation Detail for KLF15


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Basic Information Top
Gene Symbol:KLF15 ( DKFZp779M1320,KKLF )
Gene Full Name: Kruppel-like factor 15
Band: 3q21.3
Quick LinksEntrez ID:28999; OMIM: 606465; Uniprot ID:KLF15_HUMAN; ENSEMBL ID: ENSG00000163884; HGNC ID: 14536
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma8 / 10688374
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal13 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney8 / 21177737
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221302_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte4
AdrenalCortex4.15
Adrenalgland3.4
Amygdala4.35
Appendix4.1
AtrioventricularNode3.35
BDCA4+_DentriticCells4.4
Bonemarrow4
BronchialEpithelialCells4
CD105+_Endothelial4.1
CD14+_Monocytes4.3
CD19+_BCells(neg._sel.)4.25
CD33+_Myeloid5.2
CD34+5.15
CD4+_Tcells4.35
CD56+_NKCells4.85
CD71+_EarlyErythroid3.85
CD8+_Tcells3.9
CardiacMyocytes5
Caudatenucleus3.6
Cerebellum3.25
CerebellumPeduncles4.55
CiliaryGanglion2.85
CingulateCortex4.65
Colorectaladenocarcinoma4.05
DorsalRootGanglion3.4
FetalThyroid3.95
Fetalbrain4.5
Fetalliver3.5
Fetallung3.4
GlobusPallidus2.95
Heart5.05
Hypothalamus4.35
Kidney3.25
Leukemia_chronicMyelogenousK-5623.65
Leukemia_promyelocytic-HL-603.55
Leukemialymphoblastic(MOLT-4)3.3
Liver7.95
Lung5.45
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.15
Lymphoma_burkitts(Raji)5.75
MedullaOblongata3.75
OccipitalLobe3.65
OlfactoryBulb3.2
Ovary2.7
Pancreas3.35
PancreaticIslet4.35
ParietalLobe5
Pituitary5
Placenta4.15
Pons5.6
PrefrontalCortex5
Prostate4.75
Salivarygland3.2
SkeletalMuscle4.55
Skin3.1
SmoothMuscle4.55
Spinalcord4.3
SubthalamicNucleus3.7
SuperiorCervicalGanglion5.15
TemporalLobe3.9
Testis3.45
TestisGermCell3.45
TestisIntersitial3.4
TestisLeydigCell4
TestisSeminiferousTubule4
Thalamus4.1
Thymus3.25
Thyroid5.1
Tongue3.95
Tonsil4.65
Trachea3.4
TrigeminalGanglion4.05
Uterus3.35
UterusCorpus3.65
WholeBlood4.45
Wholebrain3.45
colon4.05
pineal_day5.06
pineal_night4.94
retina5.175
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P40805
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.09 ± 0.9
Basal Forebrain1.44 ± 0.2
Basal Part of Pons1.29 ± 0.31
Cerebellar Cortex1.46 ± 0.64
Cerebellar Nuclei1.82 ± 0.69
Claustrum2.49 ± 0.88
Epithalamus1.46 ± 0.65
Frontal Lobe1.46 ± 0.6
Globus Pallidus1.94 ± 0.31
Hypothalamus1.62 ± 0.64
Insula1.41 ± 0.6
Limbic Lobe1.65 ± 0.57
Mesencephalon1.8 ± 0.74
Myelencephalon1.68 ± 0.63
Occipital Lobe1.82 ± 0.81
Parietal Lobe1.7 ± 0.64
Pontine Tegmentum1.71 ± 0.66
Striatum1.95 ± 0.62
Subthalamus1.76 ± 0.66
Temporal Lobe1.53 ± 0.61
Thalamus1.58 ± 0.63
White Matter1.79 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Klf15CBCerebellum3.65
6.38
Klf15CTXCerebral cortex7.77
6.66
Klf15HIPHippocampal region4.56
5.31
Klf15HPFHippocampal formation3.34
4.04
Klf15HYHypothalamus2.01
1.76
Klf15LSXLateral septal complex1.91
1.34
Klf15MBMidbrain1.3
1.64
Klf15MYMedulla0.14
0.4
Klf15OLFOlfactory bulb2.76
3.18
Klf15PPons0.27
0.65
Klf15PALPallidum0.34
0.34
Klf15RHPRetrohippocampal region0.97
1.75
Klf15sAMYStriatum-like amygdalar nuclei1.44
0.99
Klf15STRStriatum0.74
0.61
Klf15STRdStriatum dorsal region0.18
0.24
Klf15STRvStriatum ventral region1.84
1.32
Klf15THThalamus0.86
0.73
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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